Financial toxicity of cancer care in low- and middle-income countries: a systematic review and meta-analysis.
Cancer
Financial toxicity
Low- and middle-income countries
Treatment
Journal
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
26
01
2021
accepted:
05
04
2022
pubmed:
26
4
2022
medline:
20
8
2022
entrez:
25
4
2022
Statut:
ppublish
Résumé
The costs associated with cancer diagnosis, treatment and care present enormous financial toxicity. However, evidence of financial toxicity associated with cancer in low- and middle-income countries (LMICs) is scarce. To determine the prevalence, determinants and how financial toxicity has been measured among cancer patients in LMICs. Four electronic databases were searched to identify studies of any design that reported financial toxicity among cancer patients in LMICs. Random-effects meta-analysis was used to derive the pooled prevalence of financial toxicity. Sub-group analyses were performed according to costs and determinants of financial toxicity. A total of 31 studies were included in this systematic review and meta-analysis. The pooled prevalence of objective financial toxicity was 56.96% (95% CI, 30.51, 106.32). In sub-group meta-analyses, the objective financial toxicity was higher among cancer patients with household size of more than four (1.17% [95% CI, 1.03, 1.32]; p = 0.02; I This study indicates that cancer diagnosis, treatment and care impose high financial toxicity on cancer patients in LMICs. Further rigorous research on cancer-related financial toxicity is needed.
Identifiants
pubmed: 35467118
doi: 10.1007/s00520-022-07044-z
pii: 10.1007/s00520-022-07044-z
pmc: PMC9385791
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
7159-7190Informations de copyright
© 2022. The Author(s).
Références
Asia Pac J Clin Oncol. 2018 Jun;14(3):167-178
pubmed: 28670694
BMC Med Res Methodol. 2007 Jan 15;7:4
pubmed: 17224044
Cancer Pract. 1994 May-Jun;2(3):187-93
pubmed: 8055022
BMC Public Health. 2020 Jun 22;20(1):984
pubmed: 32571275
Support Care Cancer. 2020 Dec;28(12):5693-5708
pubmed: 32865673
BMC Health Serv Res. 2018 Apr 10;18(1):261
pubmed: 29631577
BMC Palliat Care. 2019 May 23;18(1):43
pubmed: 31122235
Eur J Breast Health. 2019 Oct 01;15(4):242-248
pubmed: 31620683
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120
BMJ Support Palliat Care. 2022 Jul;12(e2):e211-e218
pubmed: 31615764
BMC Cancer. 2018 Apr 17;18(1):435
pubmed: 29665788
J Cancer Res Ther. 2018 Jan;14(1):163-170
pubmed: 29516981
Glob Health Action. 2013 Feb 04;6:18872
pubmed: 23394855
Respirology. 2016 May;21(4):626-37
pubmed: 27099100
Support Care Cancer. 2020 Apr;28(4):1703-1715
pubmed: 31292755
Ann Oncol. 2019 Jul 1;30(7):1061-1070
pubmed: 31046080
Psychooncology. 2007 Sep;16(9):796-804
pubmed: 17177268
J Cancer. 2018 Jul 30;9(17):3038-3045
pubmed: 30210626
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Surgery. 2015 Jun;157(6):971-82
pubmed: 25934082
Health Qual Life Outcomes. 2019 Jun 13;17(1):102
pubmed: 31196089
J Natl Cancer Inst. 2016 Oct 20;109(2):
pubmed: 27754926
Soc Sci Med. 2014 Oct;119:36-44
pubmed: 25137646
Front Psychol. 2017 Oct 09;8:1756
pubmed: 29062296
EClinicalMedicine. 2020 Jan 31;20:100269
pubmed: 32300733
Cancer Med. 2018 Aug;7(8):4036-4043
pubmed: 29923330
Lancet Oncol. 2012 Aug;13(8):790-801
pubmed: 22658655
J Med Assoc Thai. 2012 Jul;95 Suppl 7:S196-200
pubmed: 23130454
Int J Clin Pharm. 2013 Dec;35(6):1245-50
pubmed: 24104762
Cancer. 2017 Feb 1;123(3):476-484
pubmed: 27716900
J Natl Cancer Inst. 2015 Dec 11;108(5):
pubmed: 26657334
Cancer. 2020 Jul 15;126(14):3312-3321
pubmed: 32396242
J Trauma Acute Care Surg. 2019 Nov;87(5):1189-1196
pubmed: 31233442
J Glob Health. 2019 Dec;9(2):020702
pubmed: 31673344
Tuberk Toraks. 2007;55(1):51-8
pubmed: 17401794
J Pain Symptom Manage. 2019 Mar;57(3):646-660.e1
pubmed: 30550833
J Surg Oncol. 2019 Jul;120(1):85-92
pubmed: 30650186
Cancer. 2014 Oct 15;120(20):3245-53
pubmed: 24954526
Eur J Cancer Care (Engl). 2012 May;21(3):377-83
pubmed: 21955041
J Oncol Pract. 2019 Jun;15(6):e537-e546
pubmed: 31112479
BMC Res Notes. 2015 Aug 13;8:347
pubmed: 26268701
Support Care Cancer. 2018 Apr;26(4):1265-1272
pubmed: 29105024
Support Care Cancer. 2022 Sep;30(9):7159-7190
pubmed: 35467118
Oncologist. 2015 Jul;20(7):780-8
pubmed: 26032138
Cancers (Basel). 2021 Oct 07;13(19):
pubmed: 34638499
Patient. 2017 Jun;10(3):295-309
pubmed: 27798816
Oncologist. 2015 Dec;20(12):1378-85
pubmed: 26512045
Int J Equity Health. 2017 Oct 10;16(1):180
pubmed: 29017542
Asian Pac J Cancer Prev. 2018 Jun 25;19(6):1727-1734
pubmed: 29938473
Lancet Oncol. 2018 Apr;19(4):e200-e208
pubmed: 29611528
CA Cancer J Clin. 2018 Mar;68(2):153-165
pubmed: 29338071
Health Care Women Int. 2018 Apr;39(4):442-449
pubmed: 29125392
Health Qual Life Outcomes. 2017 Jul 17;15(1):144
pubmed: 28716032
J Med Econ. 2018 Sep;21(9):878-887
pubmed: 29860920
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Surgery. 2020 Jul;168(1):167-172
pubmed: 32197785
Int J Technol Assess Health Care. 2015 Jan;31(4):264-70
pubmed: 26353902