Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus.
Animals
Anti-Bacterial Agents
/ pharmacology
Anti-Infective Agents
Antimicrobial Cationic Peptides
/ pharmacology
Biofilms
Methicillin
Methicillin-Resistant Staphylococcus aureus
Mice
Microbial Sensitivity Tests
Peptoids
/ pharmacology
Staphylococcal Infections
/ drug therapy
Staphylococcus aureus
Cathelicidins
Staphylococcus aureus
antimicrobial peptides
chemical synthesis
Journal
Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614
Informations de publication
Date de publication:
29 06 2022
29 06 2022
Historique:
pubmed:
26
4
2022
medline:
2
7
2022
entrez:
25
4
2022
Statut:
ppublish
Résumé
Staphylococcus aureus is one of the most common pathogens associated with infection in wounds. The current standard of care uses a combination of disinfection and drainage followed by conventional antibiotics such as methicillin. Methicillin and vancomycin resistance has rendered these treatments ineffective, often causing the reemergence of infection. This study examines the use of antimicrobial peptoids (sequence-specific poly-
Identifiants
pubmed: 35467395
doi: 10.1128/spectrum.00534-22
pmc: PMC9241801
doi:
Substances chimiques
Anti-Bacterial Agents
0
Anti-Infective Agents
0
Antimicrobial Cationic Peptides
0
Peptoids
0
Methicillin
Q91FH1328A
Cathelicidins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0053422Subventions
Organisme : NIA NIH HHS
ID : DP1 AG072438
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI104960
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI149383
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI072666
Pays : United States
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