Changes in Cough Reflex Sensitivity in Children After Removal of Hypertrophied Adenoid Tissue.
adenoidectomy
adenoids
children
chronic cough
cough
cough reflex sensitivity
Journal
Journal of asthma and allergy
ISSN: 1178-6965
Titre abrégé: J Asthma Allergy
Pays: New Zealand
ID NLM: 101543450
Informations de publication
Date de publication:
2022
2022
Historique:
received:
30
12
2021
accepted:
16
03
2022
entrez:
26
4
2022
pubmed:
27
4
2022
medline:
27
4
2022
Statut:
epublish
Résumé
The co-occurrence of adenoids and chronic cough is common in children. The goal of this research was to specify changes in cough reflex sensitivity as a result of adenoid tissue removal. The sample group consisted of 17 children (six boys and 11 girls, aged 4-12 years, mean age 6.24 years), all of them possessing symptoms of chronic cough and adenoids, confirmed by nasal fiberoptic endoscopy. This sample group underwent cough reflex sensitivity assessment, which took place both prior to and after endoscopic adenoidectomy. The definition of the cough reflex sensitivity is the lowest capsaicin concentration that caused two (C2) or five (C5) coughs. Capsaicin aerosol in ascending concentrations (from 0.61 to 1250 µmol/L) was inhaled by a single-breath method (KoKo DigiDoser), with the addition of an inspiratory flow regulator valve (RIFR). Concentrations of capsaicin causing two (C2) and five coughs (C5) were reported. Cough sensitivity (geometric mean with 95% CI) for C2 was 31.86 (12.98-78.18) µmol/L preoperatively and 11.97 (6.16-23.26) µmol/L postoperatively ( In our study, adenoidectomy significantly increased cough reflex sensitivity in non-atopic children suffering from chronic cough.
Identifiants
pubmed: 35469259
doi: 10.2147/JAA.S347355
pii: 347355
pmc: PMC9034841
doi:
Types de publication
Journal Article
Langues
eng
Pagination
517-524Informations de copyright
© 2022 Sojak et al.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare in this work.
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