Restoration of Follicular T Regulatory/Helper Cell Balance by OX40L-JAG1 Cotreatment Suppresses Lupus Nephritis in NZBWF1/j Mice.

Animals Germinal Center Lupus Nephritis / metabolism Mice T Follicular Helper Cells T-Lymphocytes, Helper-Inducer T-Lymphocytes, Regulatory

Journal

Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R

Informations de publication

Date de publication:
01 06 2022
Historique:
received: 14 01 2022
accepted: 17 03 2022
pubmed: 27 4 2022
medline: 25 5 2022
entrez: 26 4 2022
Statut: ppublish

Résumé

Class-switched antinuclear autoantibodies produced by T follicular helper (TFH) cell-dependent germinal center (GC) B cell response play an essential pathogenic role in lupus nephritis (LN). The role of T follicular regulatory (TFR) cells, an effector subset of CD4

Identifiants

DOI: 10.4049/jimmunol.2200057 PMID: 35470257
pubmed: 35470257
pii: jimmunol.2200057
doi: 10.4049/jimmunol.2200057
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

2467-2481

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI107516
Pays : United States

Informations de copyright

Copyright © 2022 by The American Association of Immunologists, Inc.

Auteurs

Prabhakaran Kumar (P)

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL.
ORCID: 0000-0002-0657-6938

Sivasangari Balakrishnan (S)

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL.

Swarali Surendra Lele (S)

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL.

Suman Setty (S)

Department of Pathology, University of Illinois College of Medicine, Chicago, IL; and.

Shaurya Dhingra (S)

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL.

Alan L Epstein (AL)

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA.
ORCID: 0000-0002-1834-7729

Bellur S Prabhakar (BS)

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL; bprabhak@uic.edu.
ORCID: 0000-0001-9815-9850

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Noeuds lymphatiques › Centre germinatif › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Lupus érythémateux disséminé › Glomérulonéphrite lupique › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T auxiliaires › Lymphocytes T auxiliaires folliculaires › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T auxiliaires › Restoration of Follicular T Regulatory/Helper...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › Restoration of Follicular T Regulatory/Helper...