Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies.

Boron Compounds Cell Line, Tumor Cisplatin / chemistry Drug Delivery Systems Humans Palladium / chemistry

Journal

Dalton transactions (Cambridge, England : 2003)
ISSN: 1477-9234
Titre abrégé: Dalton Trans
Pays: England
ID NLM: 101176026

Informations de publication

Date de publication:
17 May 2022
Historique:
pubmed: 27 4 2022
medline: 19 5 2022
entrez: 26 4 2022
Statut: epublish

Résumé

With the aim of designing new metallosupramolecular architectures for drug delivery, research has focused on porous 3-dimensional (3D)-metallacages able to encapsulate cytotoxic agents protecting them from metabolism while targeting them to cancer sites. Here, two self-assembled [Pd

Identifiants

DOI: 10.1039/d2dt00337f PMID: 35470841
pubmed: 35470841
doi: 10.1039/d2dt00337f
doi:

Substances chimiques

4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 0
Boron Compounds 0
Palladium 5TWQ1V240M
Cisplatin Q20Q21Q62J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7476-7490

Auteurs

Brech Aikman (B)

Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.
ORCID: 0000-0001-8946-7421

Riccardo Bonsignore (R)

Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.
Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale delle Scienze, Edificio 17, 90128 Palermo, Italy.
ORCID: 0000-0003-2699-4384

Ben Woods (B)

Institute of Structural and Molecular Biology and Department of Biological Sciences, School of Science, Birkbeck University of London, Malet Street, London WC1E 7HX, UK.

Daniel Doellerer (D)

Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
ORCID: 0000-0001-8973-9968

Riccardo Scotti (R)

Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.

Claudia Schmidt (C)

Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.
ORCID: 0000-0001-8532-2604

Alexandra A Heidecker (AA)

Catalysis Research Center & Department of Chemistry, Chair of Inorganic and Metal-Organic Chemistry, Technical University of Munich, Ernst-Otto-Fischer Str. 1, D-85748 Garching b. München, Germany.

Alexander Pöthig (A)

Catalysis Research Center & Department of Chemistry, Chair of Inorganic and Metal-Organic Chemistry, Technical University of Munich, Ernst-Otto-Fischer Str. 1, D-85748 Garching b. München, Germany.
ORCID: 0000-0003-4663-3949

Edward J Sayers (EJ)

School of Pharmacy and Pharmaceutical Sciences, Cardiff University, CF10 3NB Cardiff, Wales, UK.
ORCID: 0000-0002-2621-1119

Arwyn T Jones (AT)

School of Pharmacy and Pharmaceutical Sciences, Cardiff University, CF10 3NB Cardiff, Wales, UK.
ORCID: 0000-0003-2781-8905

Angela Casini (A)

Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 Garching b. München, Germany. angela.casini@tum.de.
Munich Data Science Institute, Technical University of Munich, D-85748 Garching b. München, Germany.
ORCID: 0000-0003-1599-9542

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Composés du bore › Highly-fluorescent BODIPY-functionalised...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Highly-fluorescent BODIPY-functionalised...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du platine › Cisplatine › Highly-fluorescent BODIPY-functionalised...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Highly-fluorescent BODIPY-functionalised...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Highly-fluorescent BODIPY-functionalised...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Palladium › Highly-fluorescent BODIPY-functionalised...