Asymptomatic bacteriospermia and infertility-what is the connection?
Bacteriospermia
Infertility
Spermiogram
Urinary tract infection
Journal
Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
29
12
2021
accepted:
04
04
2022
pubmed:
27
4
2022
medline:
1
12
2022
entrez:
26
4
2022
Statut:
ppublish
Résumé
To determine the impact of asymptomatic bacteriospermia on semen quality in subfertile men. We conducted a retrospective, single-centre cohort study in 1300 subfertile men. In those diagnosed with asymptomatic bacteriospermia we performed univariate and multivariate logistic regression models to evaluate the strain-specific association with semen parameters. Asymptomatic bacteriospermia was diagnosed in 3.2% of patients. The microbiological semen analysis revealed a poly-microbial result in 60%. The most common bacterial species were coagulase-negative Staphylococci species (71.4%), Streptococcus viridans (50.0%) and Enterococcus faecalis (26.2%). Sexually transmitted pathogens were identified in 11.9% of semen samples. The detection of Streptococcus viridians or Haemophilus parainfluenzae correlated with impaired sperm morphology (p < 0.05). The presence of coagulase-negative Staphylococci species or Enterococcus faecalis was associated with pathological low counts of live spermatozoa (p < 0.05). In multivariate analysis only Enterococcus faecalis showed a significant impact on sperm concentration (OR 4.48; 95% CI 1.06-22.10; p = 0.041). Asymptomatic bacteriospermia has always been a subject of great controversy. There is still an ongoing debate whether to treat or not to treat. Here, we demonstrate that asymptomatic bacteriospermia is clearly associated with impaired semen quality. Our findings speak in favour of strain-specific interactions with semen parameters. Especially Enterococcus faecalis seriously affects sperm concentration.
Identifiants
pubmed: 35471630
doi: 10.1007/s15010-022-01828-5
pii: 10.1007/s15010-022-01828-5
pmc: PMC9705509
doi:
Substances chimiques
Coagulase
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1499-1505Informations de copyright
© 2022. The Author(s).
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