High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study.


Journal

BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539

Informations de publication

Date de publication:
26 04 2022
Historique:
received: 27 10 2021
accepted: 28 03 2022
entrez: 27 4 2022
pubmed: 28 4 2022
medline: 29 4 2022
Statut: epublish

Résumé

Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention. This cross-sectional study included 4284 subjects, mean age 46 ± 16SD, 56.4% females and mean BMI 26.6 ± 3.7 SD. Data were collected through a screening campaign in rural area of Kirehe District, Eastern of Rwanda, with the objective to characterize and examine the prevalence of elevated blood pressure (BP) and other CVD risk factors. An adapted tool from the World Health Organization STEPwise Approach was used for data collection. Elevated BP was defined as ≥ 140/90 mm/Hg and elevated blood glucose as blood glucose ≥ 100 mg/dL after a 6-h fast. Of the sampled population, 21.2% (n = 910) had an elevated BP at screening; BP was elevated among individuals not previously known to have HTN in 18.7% (n = 752). Among individuals with a prior diagnosis of HTN, 62.2% (n = 158 of 254) BP was uncontrolled. Age, weight, smoking, alcohol history and waist circumference were associated with BP in both univariate analyses and multivariate analysis. High rates of elevated BP identified through a health screening campaign in this Rwandan district were surprising given the rural characteristics of the district and relatively low population age. These data highlight the need to implement an adequate strategy for the prevention, diagnosis, and control of HTN that includes rural areas of Rwanda as part of a multicomponent strategy for CVD prevention.

Sections du résumé

BACKGROUND
Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention.
DESIGN AND METHOD
This cross-sectional study included 4284 subjects, mean age 46 ± 16SD, 56.4% females and mean BMI 26.6 ± 3.7 SD. Data were collected through a screening campaign in rural area of Kirehe District, Eastern of Rwanda, with the objective to characterize and examine the prevalence of elevated blood pressure (BP) and other CVD risk factors. An adapted tool from the World Health Organization STEPwise Approach was used for data collection. Elevated BP was defined as ≥ 140/90 mm/Hg and elevated blood glucose as blood glucose ≥ 100 mg/dL after a 6-h fast.
RESULTS
Of the sampled population, 21.2% (n = 910) had an elevated BP at screening; BP was elevated among individuals not previously known to have HTN in 18.7% (n = 752). Among individuals with a prior diagnosis of HTN, 62.2% (n = 158 of 254) BP was uncontrolled. Age, weight, smoking, alcohol history and waist circumference were associated with BP in both univariate analyses and multivariate analysis.
CONCLUSION
High rates of elevated BP identified through a health screening campaign in this Rwandan district were surprising given the rural characteristics of the district and relatively low population age. These data highlight the need to implement an adequate strategy for the prevention, diagnosis, and control of HTN that includes rural areas of Rwanda as part of a multicomponent strategy for CVD prevention.

Identifiants

pubmed: 35473501
doi: 10.1186/s12872-022-02606-9
pii: 10.1186/s12872-022-02606-9
pmc: PMC9044706
doi:

Substances chimiques

Blood Glucose 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

197

Informations de copyright

© 2022. The Author(s).

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Auteurs

Evariste Ntaganda (E)

Rwanda Biomedical Center (RBC), Rwanda Ministry of Health, Kigali, Rwanda.

Regine Mugeni (R)

Rwamagana Provincial Hospital, Rwamagana, Eastern Province, Rwanda. pacisreg@gmail.com.

Emmanuel Harerimana (E)

Partners in Health (PIH)/Inshuti Mu Buzima, Rwinkwavu, Rwanda.

Gedeon Ngoga (G)

Partners in Health (PIH)/Inshuti Mu Buzima, Rwinkwavu, Rwanda.

Symaque Dusabeyezu (S)

Partners in Health (PIH)/Inshuti Mu Buzima, Rwinkwavu, Rwanda.

Francois Uwinkindi (F)

Rwanda Biomedical Center (RBC), Rwanda Ministry of Health, Kigali, Rwanda.

Jean N Utumatwishima (JN)

Rwamagana Provincial Hospital, Rwamagana, Eastern Province, Rwanda.

Eugene Mutimura (E)

National Council for Science and Technology (NCST), Kigali, Rwanda.

Victor G Davila-Roman (VG)

Cardiovascular Division, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Kenneth Schechtman (K)

Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA.

Aurore Nishimwe (A)

Regional Alliance for Sustainable Development (RASD Rwanda), Kigali, Rwanda.
School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.

Laurence Twizeyimana (L)

Regional Alliance for Sustainable Development (RASD Rwanda), Kigali, Rwanda.

Angela L Brown (AL)

Cardiovascular Division, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

W Todd Cade (WT)

Duke University School of Medicine, Durham, NC, 27710, USA.

Marcus Bushaku (M)

Regional Alliance for Sustainable Development (RASD Rwanda), Kigali, Rwanda.

Lisa de Las Fuentes (L)

Cardiovascular Division, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Dominic Reeds (D)

Cardiovascular Division, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Marc Twagirumukiza (M)

School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

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