Evaluation of electropolymerized molecularly imprinted polymers (E-MIPs) on disposable electrodes for detection of SARS-CoV-2 in saliva.
Biosensor
COVID-19
Electrochemical impedance spectroscopy
Electrochemical polymerization
Molecularly imprinted polymers
SARS-CoV-2
Journal
Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534
Informations de publication
Date de publication:
08 May 2022
08 May 2022
Historique:
received:
21
01
2022
revised:
18
03
2022
accepted:
25
03
2022
entrez:
27
4
2022
pubmed:
28
4
2022
medline:
29
4
2022
Statut:
ppublish
Résumé
We investigate electropolymerized molecularly imprinted polymers (E-MIPs) for the selective recognition of SARS-CoV-2 whole virus. E-MIPs imprinted with SARS-CoV-2 pseudoparticles (pps) were electrochemically deposited onto screen printed electrodes by reductive electropolymerization, using the water-soluble N-hydroxmethylacrylamide (NHMA) as functional monomer and crosslinked with N,N'-methylenebisacrylamide (MBAm). E-MIPs for SARS-CoV-2 showed selectivity for template SARS-CoV-2 pps, with an imprinting factor of 3:1, and specificity (significance = 0.06) when cross-reacted with other respiratory viruses. E-MIPs detected the presence of SARS-CoV-2 pps in <10 min with a limit of detection of 4.9 log
Identifiants
pubmed: 35473858
pii: S0003-2670(22)00348-8
doi: 10.1016/j.aca.2022.339777
pmc: PMC8974637
pii:
doi:
Substances chimiques
Antibodies, Viral
0
Molecularly Imprinted Polymers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
339777Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/00007034
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/00007038
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/00007039
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/COV07001
Pays : United Kingdom
Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
Talanta. 2021 Apr 1;225:121977
pubmed: 33592725
Front Cell Infect Microbiol. 2020 Jun 16;10:331
pubmed: 32626666
Anal Chim Acta. 2014 Jan 27;809:155-61
pubmed: 24418147
Nanoscale. 2021 Oct 21;13(40):16885-16899
pubmed: 34528987
Lab Invest. 2022 Jan;102(1):4-13
pubmed: 34497366
J Immunol Methods. 2021 Sep;496:113096
pubmed: 34242653
Lancet Infect Dis. 2020 May;20(5):565-574
pubmed: 32213337
J Clin Virol. 2021 Mar;136:104764
pubmed: 33636553
BMC Med. 2021 Oct 1;19(1):255
pubmed: 34593004
Biosens Bioelectron. 2022 Jan 15;196:113729
pubmed: 34736101
Bioanalysis. 2016 Nov;8(21):2255-2263
pubmed: 27704931
Phys Chem Chem Phys. 2014 Aug 7;16(29):15483-9
pubmed: 24950144
J Phys Chem B. 2019 Jul 5;123(26):5432-5443
pubmed: 31150581
Mater Sci Eng C Mater Biol Appl. 2017 Aug 1;77:1341-1348
pubmed: 28532011
Front Cell Infect Microbiol. 2021 Mar 30;11:596201
pubmed: 33859951
EClinicalMedicine. 2021 Jun;36:100924
pubmed: 34101770
Biosens Bioelectron. 2021 Apr 15;178:113029
pubmed: 33515985
Nanotechnology. 2021 Feb 26;32(9):095502
pubmed: 33242844
Biosensors (Basel). 2021 May 01;11(5):
pubmed: 34062874
Expert Rev Respir Med. 2021 Aug;15(8):1035-1048
pubmed: 34253132
Sens Actuators B Chem. 2022 Feb 15;353:131160
pubmed: 34866797
Biosens Bioelectron. 2018 Feb 15;100:56-70
pubmed: 28863325
Biosens Bioelectron. 2007 Jan 15;22(6):1131-7
pubmed: 16891110
BMJ. 2021 Jul 6;374:n1637
pubmed: 34230058
Cell Host Microbe. 2020 Sep 9;28(3):445-454.e6
pubmed: 32585135
Case Rep Med. 2021 May 22;2021:6688303
pubmed: 34054967
Nat Commun. 2020 Oct 30;11(1):5493
pubmed: 33127906
J Craniofac Surg. 2020 Sep;31(6):e653-e655
pubmed: 32541273
PLoS Med. 2006 Jul;3(7):e237
pubmed: 16796401
Talanta. 2022 Apr 1;240:123158
pubmed: 34952354
Biosci Trends. 2021 Nov 21;15(5):341-344
pubmed: 34456212
Talanta. 2022 Mar 1;239:123146
pubmed: 34942484
Biomed Pharmacother. 2020 Sep;129:110499
pubmed: 32768974
Cochrane Database Syst Rev. 2020 Aug 26;8:CD013705
pubmed: 32845525
EClinicalMedicine. 2021 May;35:100865
pubmed: 33937735
Nature. 2021 May;593(7858):270-274
pubmed: 33723411
Bio Protoc. 2021 Nov 05;11(21):e4249
pubmed: 34859135
Adv Mater Interfaces. 2021 Dec 22;8(24):2101466
pubmed: 34900518
Eur J Clin Microbiol Infect Dis. 2021 Oct;40(10):2191-2198
pubmed: 33987804
Clin Infect Dis. 2020 Jul 28;71(15):841-843
pubmed: 32047895
PLoS Biol. 2020 Dec 21;18(12):e3001016
pubmed: 33347434
Med Sci Monit. 2020 Dec 17;26:e928552
pubmed: 33332288
Aging (Albany NY). 2020 Nov 1;12(21):20997-21003
pubmed: 33136068
Ann Clin Microbiol Antimicrob. 2021 May 18;20(1):35
pubmed: 34006330
J Virol Methods. 2021 Mar;289:114048
pubmed: 33358911
Biomed Pharmacother. 2020 Sep;129:110446
pubmed: 32768943
BMJ. 2021 Jul 27;374:n1676
pubmed: 34315770
Front Bioeng Biotechnol. 2019 May 24;7:115
pubmed: 31179277