Spontaneous Coassembly of the Protein Terthiophene into Fluorescent Electroactive Microfibers in 2D and 3D Cell Cultures.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
19 Apr 2022
Historique:
received: 25 11 2021
accepted: 25 02 2022
entrez: 27 4 2022
pubmed: 28 4 2022
medline: 28 4 2022
Statut: epublish

Résumé

Protein-based microfibers are biomaterials of paramount importance in materials science, nanotechnology, and medicine. Here we describe the spontaneous in situ formation and secretion of nanostructured protein microfibers in 2D and 3D cell cultures of 3T3 fibroblasts and B104 neuroblastoma cells upon treatment with a micromolar solution of either unmodified terthiophene or terthiophene modified by mono-oxygenation (thiophene → thiophene

Identifiants

pubmed: 35474798
doi: 10.1021/acsomega.1c06677
pmc: PMC9026133
doi:

Types de publication

Journal Article

Langues

eng

Pagination

12624-12636

Informations de copyright

© 2022 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Ilaria Elena Palamà (IE)

Nanotechnology Institute (CNR-NANOTEC) and Department of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.

Gabriele Maiorano (G)

Nanotechnology Institute (CNR-NANOTEC) and Department of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.

Francesca Di Maria (F)

CNR-ISOF and Mediteknology srl Area Ricerca CNR, Piero Gobetti Street 101, 40129 Bologna, Italy.

Mattia Zangoli (M)

CNR-ISOF and Mediteknology srl Area Ricerca CNR, Piero Gobetti Street 101, 40129 Bologna, Italy.

Andrea Candini (A)

CNR-ISOF and Mediteknology srl Area Ricerca CNR, Piero Gobetti Street 101, 40129 Bologna, Italy.

Alberto Zanelli (A)

CNR-ISOF and Mediteknology srl Area Ricerca CNR, Piero Gobetti Street 101, 40129 Bologna, Italy.

Stefania D'Amone (S)

Nanotechnology Institute (CNR-NANOTEC) and Department of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.

Eduardo Fabiano (E)

Institute for Microelectronics and Microsystems (CNR-IMM), Monteroni Street, 73100 Lecce, Italy.
Center for Biomolecular Nanotechnologies, UNILE Istituto Italiano di Tecnologia, Barsanti Street, 73010 Arnesano, Italy.

Giuseppe Gigli (G)

Nanotechnology Institute (CNR-NANOTEC) and Department of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.
Nanotechnology Institute (CNR-NANOTEC) and Department of Mathematics and Physics, University of Salento, Monteroni Street, 73100 Lecce, Italy.

Giovanna Barbarella (G)

CNR-ISOF and Mediteknology srl Area Ricerca CNR, Piero Gobetti Street 101, 40129 Bologna, Italy.

Classifications MeSH