Prevalence and predictive factors of nocturia in patients with obstructive sleep apnea syndrome: A retrospective cross-sectional study.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2022
2022
Historique:
received:
21
12
2021
accepted:
09
04
2022
entrez:
27
4
2022
pubmed:
28
4
2022
medline:
30
4
2022
Statut:
epublish
Résumé
Many patients with obstructive sleep apnea syndrome (OSAS) have nocturia. However, the predictive index of nocturia in patients with OSAS is currently not well known. We aimed to investigate the prevalence of nocturia in patients with OSAS and determine the factors that could predict nocturia in these patients. In this retrospective cross-sectional study, we enrolled 1,264 untreated patients with OSAS (Apnea-Hypopnea Index, AHI ≥5/h on polysomnography [PSG]) from January 2017 to January 2020. Participants completed the Beck Depression Inventory-II (BDI-II), Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), and Epworth Sleepiness Scale. Participants were divided by sex and then subdivided into nocturia and non-nocturia groups according to the following question, "Do you go to the bathroom two times or more during your sleep?" Participants' characteristics and underlying disease were investigated, and all information, including PSG data, was compared between the two groups using the t-test or chi-square test. Overall, 35.2% (337/958) of male participants with OSAS and 59.8% (183/306) of female participants with OSAS had nocturia. The nocturia group was older; scored higher on the BDI-II, PSQI, and ISI; and had more underlying disease in both sexes. There was no difference in the AHI between the two groups among both sexes, but the hypoxia-related PSG parameters and sleep quality parameters, such as higher 90% oxygen desaturation index (90% ODI), lesser N3 sleep, and higher wakefulness after sleep onset, were worse among male participants with OSAS in the nocturia group than in the non-nocturia group. In multivariate logistic analysis, 90% ODI was an independent risk factor associated with nocturia in male participants with OSAS. Considerable number of patients with OSAS had nocturia and poor sleep quality. Nocturia should be evaluated in male OSAS patients with severe hypoxia observed during sleep.
Identifiants
pubmed: 35476719
doi: 10.1371/journal.pone.0267441
pii: PONE-D-21-40265
pmc: PMC9045637
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0267441Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Int J Urol. 2012 Apr;19(4):317-29
pubmed: 22239551
Expert Rev Clin Pharmacol. 2017 Dec;10(12):1281-1293
pubmed: 29048257
Low Urin Tract Symptoms. 2019 May;11(3):139-142
pubmed: 30548821
Neurourol Urodyn. 2020 Apr;39(4):1124-1128
pubmed: 32125734
Urology. 2014 Oct;84(4):892-6
pubmed: 25096335
Arch Intern Med. 2009 Feb 23;169(4):342-50
pubmed: 19237717
Chest. 2014 Nov;146(5):1387-1394
pubmed: 25367475
Am J Lifestyle Med. 2018 Jun 18;15(3):260-268
pubmed: 34025318
J Urol. 2015 May;193(5):1692-9
pubmed: 25463994
Sleep. 2003 Feb 1;26(1):61-4
pubmed: 12627734
Am J Otolaryngol. 2022 Jan-Feb;43(1):103197
pubmed: 34492427
Sleep Breath. 2020 Dec;24(4):1293-1298
pubmed: 31907825
Urology. 2019 Nov;133S:24-33
pubmed: 31586470
Neurourol Urodyn. 2002;21(2):179-83
pubmed: 11857672
Eur Urol. 2010 Mar;57(3):488-96
pubmed: 19361907
J Clin Sleep Med. 2017 May 15;13(5):665-666
pubmed: 28416048
Medicina (Kaunas). 2020 Sep 08;56(9):
pubmed: 32911862
J Clin Neurol. 2014 Jul;10(3):210-5
pubmed: 25045373
Int Neurourol J. 2019 Jun;23(2):161-168
pubmed: 31260616
J Urol. 2006 Feb;175(2):596-600
pubmed: 16407003
Sleep Med Rev. 2003 Oct;7(5):403-11
pubmed: 14573376
Eur Urol. 2012 Nov;62(5):877-90
pubmed: 22840350
Sleep Med Rev. 2008 Dec;12(6):481-96
pubmed: 18951050
Sleep Breath. 2011 Sep;15(3):377-84
pubmed: 20358406
Urology. 2006 May;67(5):974-7
pubmed: 16635510
J Am Geriatr Soc. 2004 Jun;52(6):957-60
pubmed: 15161461
Cogn Emot. 2017 Dec;31(8):1698-1706
pubmed: 27807996
Sleep Med. 2021 Jan;77:288-294
pubmed: 33008732
Int J Urol. 2004 May;11(5):282-7
pubmed: 15147543
Sleep Breath. 2012 Sep;16(3):803-12
pubmed: 21901299
Urology. 2008 Jun;71(6):1096-8
pubmed: 18400277
Behav Sci (Basel). 2021 Dec 16;11(12):
pubmed: 34940115
J Urol. 2007 Apr;177(4):1385-9
pubmed: 17382738