Effect of Marital Status on Upper Digestive Tract Tumor Survival: Married Male Patients Exhibited a Better Prognosis.
SEER
cancer-specific survival
marital status
prognostic factors
upper digestive tract tumors
Journal
Frontiers in surgery
ISSN: 2296-875X
Titre abrégé: Front Surg
Pays: Switzerland
ID NLM: 101645127
Informations de publication
Date de publication:
2022
2022
Historique:
received:
22
02
2022
accepted:
10
03
2022
entrez:
28
4
2022
pubmed:
29
4
2022
medline:
29
4
2022
Statut:
epublish
Résumé
Marital status has been associated with the outcomes in several types of cancer, but less is known about upper digestive tract tumors (UDTTs). The study aims to explore the effect of marital status on the survival outcomes of UDTT. We collected patient cases of UDTT using the Surveillance, Epidemiology, and End Results (SEER) database between 1975 and 2016. The univariate analyses of overall survival (OS) and cancer-specific survival (CSS) were performed using the Kaplan-Meier method. The multivariate survival analyses were performed using Cox proportional hazard model. A total of 282,189 patients were included, with 56.42, 16.30, 13.33, and 13.95% of patients married, never married, divorced or separated, and widowed, respectively. The significant differences were observed among married, never-married, divorced or separated, and widowed patients with regard to the year of diagnosis, sex, age, race, pathological type, anatomical site, the number of primary tumor, grade, rate of surgery performed, radiotherapy, chemotherapy ( This study reveals that marital status is an independent prognostic factor for OS and CSS of patients with UDTT. Married male patients with UDTT trend to have a better prognosis.
Identifiants
pubmed: 35478729
doi: 10.3389/fsurg.2022.880893
pmc: PMC9035669
doi:
Types de publication
Journal Article
Langues
eng
Pagination
880893Informations de copyright
Copyright © 2022 Qing, Peng, Shang, Xu and Chen.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Nat Rev Cancer. 2006 Mar;6(3):240-8
pubmed: 16498446
Br J Cancer. 2014 Apr 29;110(9):2369-77
pubmed: 24619077
Future Oncol. 2013 Sep;9(9):1315-22
pubmed: 23980679
Sci Rep. 2017 Jan 31;7:41695
pubmed: 28139708
Psychooncology. 2010 Aug;19(8):893-7
pubmed: 20025083
Lancet Oncol. 2004 Oct;5(10):617-25
pubmed: 15465465
Breast Cancer Res Treat. 2005 Sep;93(1):41-7
pubmed: 16184457
Cancer. 2005 May 1;103(9):1819-25
pubmed: 15795905
Science. 1979 Aug 3;205(4405):513-5
pubmed: 109924
Health Aff (Millwood). 2017 Jun 1;36(6):978-981
pubmed: 28583954
J Biomed Opt. 2016 Jan;21(1):18004
pubmed: 26811077
Clin Cancer Res. 2006 Jan 15;12(2):369-75
pubmed: 16428474
Epigenetics. 2016;11(1):61-73
pubmed: 26786582
Postepy Hig Med Dosw (Online). 2017 Jun 12;71(0):485-499
pubmed: 28665278
Oncol Lett. 2020 May;19(5):3459-3468
pubmed: 32269619
Psychiatry Res. 1999 Jan 18;85(1):51-61
pubmed: 10195316
Psychooncology. 2009 Aug;18(8):866-74
pubmed: 19061195
Breast Cancer Res Treat. 2019 Nov;178(2):379-388
pubmed: 31414242
PLoS One. 2018 Mar 22;13(3):e0194277
pubmed: 29566002
Cancers (Basel). 2014 Sep 15;6(3):1793-820
pubmed: 25226287
Nat Rev Cancer. 2018 May;18(5):269-282
pubmed: 29497144
Exp Ther Med. 2016 Mar;11(3):951-956
pubmed: 26998018
Gastroenterology. 2009 Nov;137(5):1768-75
pubmed: 19698717
Oncol Lett. 2019 Aug;18(2):1904-1914
pubmed: 31423260
Cancer Med. 2019 Aug;8(10):4906-4917
pubmed: 31267686
Am J Gastroenterol. 2009 Mar;104(3):739-50
pubmed: 19240699
Int J Oncol. 2016 May;48(5):1805-14
pubmed: 26935408
J Clin Oncol. 2013 Nov 1;31(31):3869-76
pubmed: 24062405
Med Hypotheses. 2008;70(3):700-1
pubmed: 17720331
Ann Oncol. 2010 Apr;21(4):877-883
pubmed: 19822532
Breast Cancer Res Treat. 2006 Oct;99(3):313-21
pubmed: 16583264
Breast. 2017 Apr;32:13-17
pubmed: 28012410
J Cancer. 2018 Apr 27;9(10):1870-1876
pubmed: 29805714
J Gerontol A Biol Sci Med Sci. 2007 Aug;62(8):892-8
pubmed: 17702882
Cancer Epidemiol. 2011 Oct;35(5):417-22
pubmed: 21466984
Future Oncol. 2010 Dec;6(12):1863-81
pubmed: 21142861
Physiol Rev. 2007 Jul;87(3):873-904
pubmed: 17615391
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Soc Sci Med. 2007 Jan;64(1):77-94
pubmed: 17011690
Cancer. 2006 Sep 1;107(5 Suppl):1189-95
pubmed: 16835910
J Natl Cancer Inst. 2000 Jun 21;92(12):994-1000
pubmed: 10861311