Feasibility of a Machine Learning-Based Smartphone Application in Detecting Depression and Anxiety in a Generally Senior Population.

NLP artificial intelligence behavioral health monitoring biomarkers machine learning mental health screening smartphone speech

Journal

Frontiers in psychology
ISSN: 1664-1078
Titre abrégé: Front Psychol
Pays: Switzerland
ID NLM: 101550902

Informations de publication

Date de publication:
2022
Historique:
received: 08 11 2021
accepted: 01 03 2022
entrez: 28 4 2022
pubmed: 29 4 2022
medline: 29 4 2022
Statut: epublish

Résumé

Depression and anxiety create a large health burden and increase the risk of premature mortality. Mental health screening is vital, but more sophisticated screening and monitoring methods are needed. The Ellipsis Health App addresses this need by using semantic information from recorded speech to screen for depression and anxiety. The primary aim of this study is to determine the feasibility of collecting weekly voice samples for mental health screening. Additionally, we aim to demonstrate portability and improved performance of Ellipsis' machine learning models for patients of various ages. Study participants were current patients at Desert Oasis Healthcare, mean age 63 years (SD = 10.3). Two non-randomized cohorts participated: one with a documented history of depression within 24 months prior to the study (Group Positive), and the other without depression (Group Negative). Participants recorded 5-min voice samples weekly for 6 weeks Protocol completion rate was 61% for both groups. Use beyond protocol was 27% for Group Positive and 9% for Group Negative. The Ellipsis Health App showed an AUC of 0.82 for the combined groups when compared to the PHQ-8 and GAD-7 with a threshold score of 10. Performance was high for senior participants as well as younger age ranges. Additionally, many participants spoke longer than the required 5 min. The Ellipsis Health App demonstrated feasibility in using voice recordings to screen for depression and anxiety among various age groups and the machine learning models using Transformer methodology maintain performance and improve over LSTM methodology when applied to the study population.

Sections du résumé

Background UNASSIGNED
Depression and anxiety create a large health burden and increase the risk of premature mortality. Mental health screening is vital, but more sophisticated screening and monitoring methods are needed. The Ellipsis Health App addresses this need by using semantic information from recorded speech to screen for depression and anxiety.
Objectives UNASSIGNED
The primary aim of this study is to determine the feasibility of collecting weekly voice samples for mental health screening. Additionally, we aim to demonstrate portability and improved performance of Ellipsis' machine learning models for patients of various ages.
Methods UNASSIGNED
Study participants were current patients at Desert Oasis Healthcare, mean age 63 years (SD = 10.3). Two non-randomized cohorts participated: one with a documented history of depression within 24 months prior to the study (Group Positive), and the other without depression (Group Negative). Participants recorded 5-min voice samples weekly for 6 weeks
Results UNASSIGNED
Protocol completion rate was 61% for both groups. Use beyond protocol was 27% for Group Positive and 9% for Group Negative. The Ellipsis Health App showed an AUC of 0.82 for the combined groups when compared to the PHQ-8 and GAD-7 with a threshold score of 10. Performance was high for senior participants as well as younger age ranges. Additionally, many participants spoke longer than the required 5 min.
Conclusion UNASSIGNED
The Ellipsis Health App demonstrated feasibility in using voice recordings to screen for depression and anxiety among various age groups and the machine learning models using Transformer methodology maintain performance and improve over LSTM methodology when applied to the study population.

Identifiants

pubmed: 35478769
doi: 10.3389/fpsyg.2022.811517
pmc: PMC9037748
doi:

Types de publication

Journal Article

Langues

eng

Pagination

811517

Informations de copyright

Copyright © 2022 Lin, Nazreen, Rutowski, Lu, Harati, Shriberg, Chlebek and Aratow.

Déclaration de conflit d'intérêts

All authors were employed by the company Ellipsis Health Inc. The authors declare that this study received funding from Ellipsis Health Inc. Ellipsis Health Inc. had the following involvement in the study: study design, collection, analysis, interpretation of data, the writing of this article and the decision to submit it for publication.

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Auteurs

David Lin (D)

Ellipsis Health, San Francisco, CA, United States.

Tahmida Nazreen (T)

Ellipsis Health, San Francisco, CA, United States.

Tomasz Rutowski (T)

Ellipsis Health, San Francisco, CA, United States.

Yang Lu (Y)

Ellipsis Health, San Francisco, CA, United States.

Amir Harati (A)

Ellipsis Health, San Francisco, CA, United States.

Elizabeth Shriberg (E)

Ellipsis Health, San Francisco, CA, United States.

Piotr Chlebek (P)

Ellipsis Health, San Francisco, CA, United States.

Michael Aratow (M)

Ellipsis Health, San Francisco, CA, United States.

Classifications MeSH