Efficient Simulation of Arbitrary Multicomponent First-Order Binding Kinetics for Improved Assay Design and Molecular Assembly.


Journal

ACS measurement science au
ISSN: 2694-250X
Titre abrégé: ACS Meas Sci Au
Pays: United States
ID NLM: 9918232604306676

Informations de publication

Date de publication:
20 Apr 2022
Historique:
received: 13 09 2021
revised: 08 11 2021
accepted: 09 11 2021
entrez: 28 4 2022
pubmed: 29 4 2022
medline: 29 4 2022
Statut: ppublish

Résumé

Traditional enzyme-linked immunosorbent assay (ELISA), long the workhorse for specific target protein detection using microplate wells, is nearing its fundamental limit of sensitivity. New opportunities in health care call for

Identifiants

pubmed: 35479104
doi: 10.1021/acsmeasuresciau.1c00037
pmc: PMC9026241
doi:

Types de publication

Journal Article

Langues

eng

Pagination

139-146

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB031581
Pays : United States

Informations de copyright

© 2021 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare the following competing financial interest(s): K.B. and V.T.-C. declare competing financial interest as cofounders of Northern Nanopore Instruments Inc. a for-profit company which sells solid-state nanopore-related hardware and software.

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Auteurs

Kyle Briggs (K)

Department of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.

Mohamed Yassine Bouhamidi (MY)

Department of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.

Liqun He (L)

Department of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.

Vincent Tabard-Cossa (V)

Department of Physics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.

Classifications MeSH