Clinical Efficacy of Ulinastatin Combined with Meglumine Adenosine Cyclophosphate in the Treatment of Acute Myocardial Infarction.


Journal

Computational and mathematical methods in medicine
ISSN: 1748-6718
Titre abrégé: Comput Math Methods Med
Pays: United States
ID NLM: 101277751

Informations de publication

Date de publication:
2022
Historique:
received: 17 02 2022
revised: 11 03 2022
accepted: 21 03 2022
entrez: 28 4 2022
pubmed: 29 4 2022
medline: 30 4 2022
Statut: epublish

Résumé

Ulinastatin, a common adjuvant drug in the clinical treatment of acute circulatory failure, has a good effect on various inflammatory diseases. In this study, we aim to explore the clinical efficacy of ulinastatin combined with meglumine adenosine cyclophosphate in patients with acute myocardial infarction (AMI) and its effect on cardiac function and endothelial function of patients. 100 AMI patients treated in our hospital (February 2020-October 2020) were randomly chosen and divided into group J and group Q, with 50 cases in each group. Group Q was treated with meglumine adenosine cyclophosphate only, while group J was treated with ulinastatin combined with meglumine adenosine cyclophosphate to compare the treatment efficiency, cardiac structure indexes, cardiac systolic function, blood lipid levels, vascular endothelial function, QLI (quality of life) scores, BI indexes, and FMA (motor function) scores between the two groups. The treatment efficiency, QLI score, BI index, and FMA score in group J were notably higher compared with group Q (

Identifiants

pubmed: 35479188
doi: 10.1155/2022/2172412
pmc: PMC9038408
doi:

Substances chimiques

Glycoproteins 0
Meglumine 6HG8UB2MUY
Adenosine K72T3FS567
urinastatin OR3S9IF86U

Types de publication

Journal Article Randomized Controlled Trial Retracted Publication

Langues

eng

Sous-ensembles de citation

IM

Pagination

2172412

Commentaires et corrections

Type : RetractionIn

Informations de copyright

Copyright © 2022 Zhenying Zhang et al.

Déclaration de conflit d'intérêts

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

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Auteurs

Zhenying Zhang (Z)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Xiaojing Sun (X)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Jiagui Ma (J)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Qiaoyan Ma (Q)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Qian Cao (Q)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Liu Zhang (L)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Lizhong Wang (L)

Cardiac Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

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Classifications MeSH