Peripheral and Central/Intraosseous Vasoactive Infusions During and After Pediatric Critical Care Transport: Retrospective Cohort Study of Extravasation Injury.
Journal
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
ISSN: 1529-7535
Titre abrégé: Pediatr Crit Care Med
Pays: United States
ID NLM: 100954653
Informations de publication
Date de publication:
01 08 2022
01 08 2022
Historique:
pubmed:
29
4
2022
medline:
30
9
2022
entrez:
28
4
2022
Statut:
ppublish
Résumé
To compare the prevalence of adverse events related to vasoactive drug infusions administered via a peripheral venous catheter versus a central venous or intraosseous catheter. Retrospective observational study. A pediatric critical care transport team, and the PICUs and regional hospitals within the North Thames and East Anglia regions of the United Kingdom. Children (up to 18 yr old) transported by the Children's Acute Transport Service receiving an infusion of a vasoactive drug (epinephrine, dobutamine, dopamine, norepinephrine, and vasopressin). None. The medical records of all children transported between April 2017 and May 2020 receiving a vasoactive drug infusion were reviewed and cross-referenced with the service critical incident database. The outcome measure was anatomic catheter-related adverse events (including extravasation) reported during transport or in the first 24 hours on the PICU. During the study period, the service undertook 3,836 transports. Vasoactive drugs were administered during 558 patient transports (14.5%). During 198 of 558 transports (35.5%), vasoactive drugs were administered via a peripheral venous catheter, with seven of 198 (3.5%) adverse events. One extravasation event resulted in tissue necrosis. The median time to injury after the infusion was commenced was 60 minutes (interquartile range, 30-60 min). During 360 of 558 transports (64.5%), vasoactive infusions were administered by central venous or intraosseous catheter, with nine of 360 (2.5%) adverse events. During pediatric critical care transport, we did not find a difference in prevalence of adverse events following the administration of vasoactive drugs via peripheral venous catheters or via central venous and intraosseous catheters.
Identifiants
pubmed: 35481954
doi: 10.1097/PCC.0000000000002972
pii: 00130478-202208000-00006
doi:
Substances chimiques
Dobutamine
3S12J47372
Dopamine
VTD58H1Z2X
Norepinephrine
X4W3ENH1CV
Epinephrine
YKH834O4BH
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
626-634Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2022 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
Déclaration de conflit d'intérêts
The authors have disclosed that they do not have any potential conflicts of interest.
Références
Weiss SL, Peters MJ, Alhazzani W, et al.: Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatr Crit Care Med 2020; 21:e52–e106
Davis AL, Carcillo JA, Aneja RK, et al.: The American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: Executive summary. Pediatr Crit Care Med 2017; 18:884–890
Skellet S, Maconochie I, Bingham B, et al.: Resuscitation Council UK Paediatric Advanced Life Support Guidelines. Available at: https://www.resus.org.uk/library/2021-resuscitation-guidelines/paediatric-advanced-life-support-guidelines . Accessed December 18, 2021
Loubani OM, Green RS: A systematic review of extravasation and local tissue injury from administration of vasopressors through peripheral intravenous catheters and central venous catheters. J Crit Care 2015; 30:653.e9–653.17
Ramnarayan P, Polke E: The state of paediatric intensive care retrieval in Britain. Arch Dis Child 2012; 97:145–149
Lampariello S, Clement M, Aralihond AP, et al.: Stabilisation of critically ill children at the district general hospital prior to intensive care retrieval: A snapshot of current practice. Arch Dis Child 2010; 95:681–685
Inwald DP, Tasker RC, Peters MJ, et al.; Paediatric Intensive Care Society Study Group (PICS-SG): Emergency management of children with severe sepsis in the United Kingdom: The results of the Paediatric Intensive Care Society sepsis audit. Arch Dis Child 2009; 94:348–353
Seaton SE, Ramnarayan P, Davies P, et al.; DEPICT Study Team: Does time taken by paediatric critical care transport teams to reach the bedside of critically ill children affect survival? A retrospective cohort study from England and Wales. BMC Pediatr 2020; 20:301
Infusion Nurses Society: Infusion nursing standards of practice. J Infus Nurs 2006; 29(1 Suppl):S1–S92
Amjad I, Murphy T, Nylander-Housholder L, et al.: A new approach to management of intravenous infiltration in pediatric patients: Pathophysiology, classification, and treatment. J Infus Nurs 2011; 34:242–249
Owen VS, Rosgen BK, Cherak SJ, et al.: Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: A systematic review and meta-analysis. Crit Care 2021; 25:146
D’Souza M, Pye S, Randle E, et al.: Use of peripheral vasoactive drug infusions during the critical care transport of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection. Arch Dis Child 2021; 107:e11
Turner DA, Kleinman ME: The use of vasoactive agents via peripheral intravenous access during transport of critically ill infants and children. Pediatr Emerg Care 2010; 26:563–566
Kumar S, Poovazhagi V, Shanthi S: Study of vasoactive infusions through peripheral line. Pediatr Oncall J 2015; 12:31–33
Lampin ME, Rousseaux J, Botte A, et al.: Noradrenaline use for septic shock in children: Doses, routes of administration and complications. Acta Paediatr 2012; 101:e426–e430
Patregnani JT, Sochet AA, Klugman D: Short-term peripheral vasoactive infusions in pediatrics: Where is the harm? Pediatr Crit Care Med 2017; 18:e378–e381
Ventura AM, Shieh HH, Bousso A, et al.: Double-blind prospective randomized controlled trial of dopamine versus epinephrine as first-line vasoactive drugs in pediatric septic shock. Crit Care Med 2015; 43:2292–2302
Lampin ME, Rousseaux J, Botte A, et al.: Noradrenaline use for septic shock in children: Doses, routes of administration and complications. Acta Paediatr 2012; 101:e426–e430
Charbel RC, Ollier V, Julliand S, et al.: Safety of early norepinephrine infusion through peripheral vascular access during transport of critically ill children. J Am Coll Emerg Physicians Open 2021; 2:e12395