Computational fluid dynamics (CFD) analysis in a ruptured vertebral artery dissecting aneurysm implanted by Pipeline when recurrent after LVIS-assisted coiling treatment: Case report and review of the literatures.


Journal

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
ISSN: 2385-2011
Titre abrégé: Interv Neuroradiol
Pays: United States
ID NLM: 9602695

Informations de publication

Date de publication:
Aug 2023
Historique:
pmc-release: 01 08 2024
medline: 4 8 2023
pubmed: 30 4 2022
entrez: 29 4 2022
Statut: ppublish

Résumé

Hemodynamics plays an important role in the natural history of the process of rupture and recurrence of intracranial aneurysms. This study aimed to investigate the role of hemodynamics for recurrence in a vertebral artery dissecting aneurysm (VADA). A patient with a ruptured VADA firstly treated by low-profile visualized intraluminal support (LVIS)-assisted coiling, and was implanted with a Pipeline Embolization Device (PED) after aneurysm recurrence. Finite element analysis and computational fluid dynamics simulations were conducted in 6 serial imaging procedures, and the calculated hemodynamics was correlated with aneurysm recurrence. Wall shear stress (WSS) was not effectively suppressed, resulting in aneurysm recurrence with initial entry tear to occur above the protuberance after 7 months of LVIS stent-assisted coiling. With the implantation of PED, WSS, inflow stream and velocity at the aneurysm neck significantly decreased. During the 3-month follow-up after PED deployment, there was significant shrinkage of the sac and the blood flow in the sac was reduced considerably. The 27-month follow-up after PED deployment indicated the aneurysm was stable. The present case study suggests that insufficient suppression of high WSS and high inflow velocity at the neck of the parent artery, especially near the posterior inferior cerebellar artery, might be associated with aneurysm recurrence.

Sections du résumé

BACKGROUNDS BACKGROUND
Hemodynamics plays an important role in the natural history of the process of rupture and recurrence of intracranial aneurysms. This study aimed to investigate the role of hemodynamics for recurrence in a vertebral artery dissecting aneurysm (VADA).
METHODS METHODS
A patient with a ruptured VADA firstly treated by low-profile visualized intraluminal support (LVIS)-assisted coiling, and was implanted with a Pipeline Embolization Device (PED) after aneurysm recurrence. Finite element analysis and computational fluid dynamics simulations were conducted in 6 serial imaging procedures, and the calculated hemodynamics was correlated with aneurysm recurrence.
RESULTS RESULTS
Wall shear stress (WSS) was not effectively suppressed, resulting in aneurysm recurrence with initial entry tear to occur above the protuberance after 7 months of LVIS stent-assisted coiling. With the implantation of PED, WSS, inflow stream and velocity at the aneurysm neck significantly decreased. During the 3-month follow-up after PED deployment, there was significant shrinkage of the sac and the blood flow in the sac was reduced considerably. The 27-month follow-up after PED deployment indicated the aneurysm was stable.
CONCLUSIONS CONCLUSIONS
The present case study suggests that insufficient suppression of high WSS and high inflow velocity at the neck of the parent artery, especially near the posterior inferior cerebellar artery, might be associated with aneurysm recurrence.

Identifiants

pubmed: 35484808
doi: 10.1177/15910199221097766
pmc: PMC10399494
doi:

Types de publication

Review Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

442-449

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Auteurs

Linhui Chen (L)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Xiaochang Leng (X)

ArteryFlow Technology Co., Ltd. Hangzhou, China.

Chaobo Zheng (C)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Yejie Shan (Y)

ArteryFlow Technology Co., Ltd. Hangzhou, China.

Ming Wang (M)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Xiang Bao (X)

Department of Neurosurgery, Jinhua Central Hospital, Jinhua, China.

Jiong Wu (J)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Rong Zou (R)

ArteryFlow Technology Co., Ltd. Hangzhou, China.

Xiaobo Liu (X)

Department of Neurosurgery, Jinhua Central Hospital, Jinhua, China.

Shanhu Xu (S)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Jianping Xiang (J)

ArteryFlow Technology Co., Ltd. Hangzhou, China.

Shu Wan (S)

Brain Center, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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