Plant-based diet index and erectile dysfunction in the Health Professionals Follow-Up Study.

andrology erectile dysfunction health professionals follow-up study men's health plant-based diet

Journal

BJU international
ISSN: 1464-410X
Titre abrégé: BJU Int
Pays: England
ID NLM: 100886721

Informations de publication

Date de publication:
10 2022
Historique:
pubmed: 30 4 2022
medline: 16 9 2022
entrez: 29 4 2022
Statut: ppublish

Résumé

To evaluate the longitudinal association between plant-based diet index (PDI) score and incident erectile dysfunction (ED). We conducted a prospective analysis of 21 942 men aged 40 to 75 years who were enrolled in the Health Professionals Follow-Up Study. ED was assessed with questionnaires every 4 years starting in 2000. Dietary data were collected via validated food frequency questionnaires completed every 4 years and were used to calculate total PDI scores, as well as healthy (hPDI) and unhealthy (uPDI) subscores. Multivariable Cox proportional hazards models were used to compute hazard ratios (HRs) for incident ED. All models were stratified by age (<60, 60 to <70, ≥70 years). Among men aged 60 to <70 years, hPDI was inversely associated with incident ED. Those in the highest quintile of hPDI in that age group had an 18% lower risk of ED (HR 0.82, 95% confidence interval (CI) 0.73-0.91; P-trend <0.001) compared to those in the lowest quintile. Conversely, uPDI was positively associated with ED in men aged <60 years (HR 1.27, 95% CI 1.01-1.60; P-trend = 0.02). Encouraging a healthy plant-based diet may be an environmentally sustainable intervention for men interested in maintaining erectile function.

Identifiants

pubmed: 35484829
doi: 10.1111/bju.15765
pmc: PMC9474604
mid: NIHMS1827108
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

514-521

Subventions

Organisme : NIDDK NIH HHS
ID : K12 DK111028
Pays : United States

Informations de copyright

© 2022 BJU International.

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Auteurs

Heiko Yang (H)

Department of Urology, UCSF.

Benjamin N Breyer (BN)

Department of Urology, UCSF.

Eric B Rimm (EB)

Departments of Nutrition & Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital.

Edward Giovannucci (E)

Departments of Nutrition & Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital.

Stacy Loeb (S)

Department of Urology and Population Health, New York University and Manhattan Veterans Affairs.

Stacey A Kenfield (SA)

Department of Urology, UCSF.
Department of Epidemiology & Biostatistics, UCSF.

Scott R Bauer (SR)

Department of Urology, UCSF.
Division of General Internal Medicine, Department of Medicine, UCSF.
San Francisco Veterans Affairs Healthcare System.

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