Perioperative Safety Evaluation of Gastrointestinal Surgery in Patients With Prosthetic Valves.


Journal

The heart surgery forum
ISSN: 1522-6662
Titre abrégé: Heart Surg Forum
Pays: United States
ID NLM: 100891112

Informations de publication

Date de publication:
25 Apr 2022
Historique:
received: 27 12 2021
accepted: 07 03 2022
entrez: 29 4 2022
pubmed: 30 4 2022
medline: 4 5 2022
Statut: epublish

Résumé

In patients with prosthetic valves, the perioperative outcomes, as well as the risk factors, following gastrointestinal surgery remain to be defined.  Methods: From January 2010 to March 2018, the clinical data of 69 cases with prosthetic valves after gastrointestinal surgery retrospectively were collected. Univariate and multivariate analysis were applied to identify the risk factors associated with significant bleeding events and non-hemorrhagic complications. Among 69 cases, 9 patients (13.0%) presented major bleeding events, and 21 patients (30.4%) presented non-hemorrhagic complications. Major bleeding events were significantly higher in patients with simple aortic valve replacement (AVR) than in other types of prosthetic valves (27.6% vs. 2.5%, P = 0.003), and there was no significant difference in the incidence of non-hemorrhagic complications. Simple AVR was the significant risk factor for major bleeding events (P = 0.043). Significant risk factors for non-hemorrhagic complications were operative duration ≥ 160 minutes (P = 0.021), duration from heart valve replacement to gastrointestinal surgery ≥ 84 months (P = 0.039), and simple AVR (P = 0.047). The patients with simple AVR had a much higher bleeding risk following gastrointestinal surgery.

Sections du résumé

BACKGROUND BACKGROUND
In patients with prosthetic valves, the perioperative outcomes, as well as the risk factors, following gastrointestinal surgery remain to be defined.  Methods: From January 2010 to March 2018, the clinical data of 69 cases with prosthetic valves after gastrointestinal surgery retrospectively were collected. Univariate and multivariate analysis were applied to identify the risk factors associated with significant bleeding events and non-hemorrhagic complications.
RESULTS RESULTS
Among 69 cases, 9 patients (13.0%) presented major bleeding events, and 21 patients (30.4%) presented non-hemorrhagic complications. Major bleeding events were significantly higher in patients with simple aortic valve replacement (AVR) than in other types of prosthetic valves (27.6% vs. 2.5%, P = 0.003), and there was no significant difference in the incidence of non-hemorrhagic complications. Simple AVR was the significant risk factor for major bleeding events (P = 0.043). Significant risk factors for non-hemorrhagic complications were operative duration ≥ 160 minutes (P = 0.021), duration from heart valve replacement to gastrointestinal surgery ≥ 84 months (P = 0.039), and simple AVR (P = 0.047).
CONCLUSION CONCLUSIONS
The patients with simple AVR had a much higher bleeding risk following gastrointestinal surgery.

Identifiants

pubmed: 35486049
doi: 10.1532/hsf.4533
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E305-E313

Auteurs

Ling Chen (L)

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. drlchen@163.com.

Jie Sun (J)

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. herowings@foxmail.com.

Hao Chen (H)

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. hyschen@163.com.

Fenglin Liu (F)

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. Liu_Fenglin_zs@163.com.

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