Evolution of corneal transplantation techniques and their indications in a French corneal transplant unit in 2000-2020.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
09
2021
accepted:
24
01
2022
entrez:
29
4
2022
pubmed:
30
4
2022
medline:
4
5
2022
Statut:
epublish
Résumé
This retrospective cohort study assessed the evolution of corneal transplantation and its indications in the last 21 years (2000-2020) in a specialized ophthalmology department in a tertiary referral center in France. The surgical techniques and indications, patient age and sex, and postoperative best-corrected visual acuity (BCVA) 6 months after keratoplasty were extracted. In total, 1042 eyes underwent keratoplasty in 2000-2020. Annual numbers of corneal transplantations increased by 2.2-fold. Penetrating keratoplasty (PKP) was the sole technique for the first 11 years. Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) were introduced in 2011 and 2014, respectively. Cases of both quickly increased, accounting for 28% and 41% of cases in 2015-2020, respectively. Eventually, DSAEK and DMEK were respectively used for most pseudophakic bullous keratopathy (PBK) and all Fuchs endothelial cell dystrophy (FECD) cases. PKP cases declined to 27%. Deep anterior lamellar keratoplasty (DALK) was rare (3% of all cases). These changes associated with rises in PBK and particularly FECD cases, and a strong decline in keratoconus, causing FECD, PBK, and keratoconus to move from being the 4th, 1st, and 3rd most common indications to the 1st, 2nd, and 6th, respectively. On average, BCVA improved by 0.1-0.3 logMAR. Patient age dropped steadily over time. Female predominance was observed. The invention of DSAEK and then DMEK precipitated an enormous change in clinical practice and a large expansion of keratoplasty to new indications. This study confirms and extends previous findings in other countries.
Identifiants
pubmed: 35486609
doi: 10.1371/journal.pone.0263686
pii: PONE-D-21-29757
pmc: PMC9053824
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0263686Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Clin Ophthalmol. 2018 Jun 07;12:1049-1059
pubmed: 29922034
PLoS One. 2017 Dec 18;12(12):e0182275
pubmed: 29252983
Cornea. 2001 Apr;20(3):239-43
pubmed: 11322409
Cornea. 2006 Sep;25(8):886-9
pubmed: 17102661
Am J Ophthalmol. 2014 Dec;158(6):1239-46
pubmed: 25174894
Arch Ophthalmol. 2012 May;130(5):621-8
pubmed: 22652847
J Ophthalmol. 2018 Jul 18;2018:9132083
pubmed: 30079255
Ophthalmology. 2015 Dec;122(12):2432-42
pubmed: 26386848
Am J Ophthalmol. 2016 Oct;170:133-142
pubmed: 27497603
Br J Ophthalmol. 2017 Jun;101(6):834-838
pubmed: 27635063
Cornea. 2016 Dec;35(12):1526-1532
pubmed: 27560035
Cornea. 2006 Sep;25(8):987-90
pubmed: 17102683
Ophthalmology. 2009 Dec;116(12):2361-8
pubmed: 19875170
Cornea. 2002 Apr;21(3):325-7
pubmed: 11917186
Ophthalmology. 2005 Sep;112(9):1541-8
pubmed: 16005975
Trans Am Ophthalmol Soc. 2015;113:T10
pubmed: 26755854
Cornea. 2017 Dec;36(12):1445-1451
pubmed: 28957976
Eye (Lond). 2020 Mar;34(3):427-441
pubmed: 31267087
Ophthalmology. 2020 Sep;127(9):1152-1159
pubmed: 32386811
Cornea. 2015 Aug;34(8):880-7
pubmed: 26057325
Oman J Ophthalmol. 2013 Sep;6(Suppl 1):S12-7
pubmed: 24391366
Am J Ophthalmol. 2003 May;135(5):620-7
pubmed: 12719068
Cornea. 1998 Nov;17(6):618-26
pubmed: 9820943
Cornea. 2017 Mar;36(3):275-279
pubmed: 27918355
Cornea. 2004 Apr;23(3):286-8
pubmed: 15084862
Am J Ophthalmol. 1956 Mar;41(3):530-3
pubmed: 13302358
J Ophthalmol. 2013;2013:894319
pubmed: 24223301
Indian J Ophthalmol. 2013 Aug;61(8):382-3
pubmed: 23925318
J Cataract Refract Surg. 2011 Dec;37(12):2137-43
pubmed: 22108109
J Cataract Refract Surg. 2003 Sep;29(9):1780-5
pubmed: 14522301
Refract Corneal Surg. 1989 Jul-Aug;5(4):258-61
pubmed: 2488816
Acta Ophthalmol. 2016 Nov;94(7):675-678
pubmed: 27213687
Br J Ophthalmol. 2012 Mar;96(3):405-8
pubmed: 21733923
Curr Opin Ophthalmol. 2013 Jul;24(4):329-35
pubmed: 23680758
Clin Exp Ophthalmol. 2012 Mar;40(2):141-7
pubmed: 21902782
Exp Ther Med. 2020 Sep;20(3):2794-2804
pubmed: 32765774
Transplant Proc. 2016 Jun;48(5):1818-23
pubmed: 27496499
Am J Ophthalmol. 2018 Apr;188:91-98
pubmed: 29410297
Eur J Ophthalmol. 2019 Jan;29(1):15-22
pubmed: 29661044
Int Ophthalmol. 2021 Jul;41(7):2315-2328
pubmed: 34117964
Ophthalmology. 2011 Dec;118(12):2368-73
pubmed: 21872938
J Clin Med. 2021 May 29;10(11):
pubmed: 34072608
Graefes Arch Clin Exp Ophthalmol. 2015 Jun;253(6):895-900
pubmed: 25631845
Cornea. 2017 Jan;36(1):1-6
pubmed: 27811564
Ann Transplant. 2017 Dec 15;22:749-754
pubmed: 29242495
J Ophthalmic Vis Res. 2020 Apr 06;15(2):149-159
pubmed: 32308948
J Refract Surg. 2008 Sep;24(7):S720-5
pubmed: 18811118
Surv Ophthalmol. 2015 Nov-Dec;60(6):509-23
pubmed: 25980780
Acta Ophthalmol. 2009 May;87(3):310-4
pubmed: 19302079
Cornea. 2014 Mar;33(3):252-6
pubmed: 24457452
Can J Ophthalmol. 2011 Aug;46(4):360-6
pubmed: 21816258
J Optom. 2014 Jul-Sep;7(3):113-24
pubmed: 25000866
Acta Ophthalmol. 2013 Mar;91(2):145-50
pubmed: 22672202
Exp Eye Res. 1998 Jan;66(1):97-103
pubmed: 9533835
Cornea. 2017 Nov;36(11):1437-1443
pubmed: 28834814
Int J Ophthalmol. 2016 Jan 18;9(1):48-52
pubmed: 26949609
Eur J Ophthalmol. 2018 Sep;28(5):535-540
pubmed: 29649920
Expert Rev Med Devices. 2014 Nov;11(6):573-9
pubmed: 25101685
Cornea. 2009 Jun;28(5):485-8
pubmed: 19421053
J Cataract Refract Surg. 2008 May;34(5):796-801
pubmed: 18471635
Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2217-22
pubmed: 26216795