Hyponatremia in Cirrhosis.
Albumin
Arginine vasopressin
Ascites
Central pontine myelinolysis
Cirrhosis
Hyponatremia
Liver transplantation
Osmotic demyelination syndrome
Journal
Clinics in liver disease
ISSN: 1557-8224
Titre abrégé: Clin Liver Dis
Pays: United States
ID NLM: 9710002
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
entrez:
29
4
2022
pubmed:
30
4
2022
medline:
4
5
2022
Statut:
ppublish
Résumé
Hyponatremia is the most common electrolyte disorder encountered in clinical practice, and it is a common complication of cirrhosis reflecting an increase in nonosmotic secretion of arginine vasopressin as a result of of the circulatory dysfunction that is characteristic of advanced liver disease. Hyponatremia in cirrhosis has been associated with poor clinical outcomes including increased risk of morbidity and mortality, poor quality of life, and heightened health care utilization. Despite this, the treatment of hyponatremia in cirrhosis remains challenging as conventional therapies such as fluid restriction are frequently ineffective. In this review, we discuss the epidemiology, clinical outcomes, pathogenesis, etiology, evaluation, and management of hyponatremia in cirrhosis.
Identifiants
pubmed: 35487602
pii: S1089-3261(22)00001-0
doi: 10.1016/j.cld.2022.01.001
pmc: PMC9060324
mid: NIHMS1769946
pii:
doi:
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
149-164Subventions
Organisme : NIDDK NIH HHS
ID : R21 DK122023
Pays : United States
Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
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