SARS-CoV-2 Infection Rates Following Use of Regular Compared With Defective Respirators When Caring for COVID-19 Patients: A Retrospective Follow-up Study.


Journal

Annals of work exposures and health
ISSN: 2398-7316
Titre abrégé: Ann Work Expo Health
Pays: England
ID NLM: 101698454

Informations de publication

Date de publication:
12 01 2023
Historique:
received: 23 12 2021
revised: 22 03 2022
accepted: 19 04 2022
pubmed: 1 5 2022
medline: 14 1 2023
entrez: 30 4 2022
Statut: ppublish

Résumé

There is strong observational evidence that respirators are highly effective in protecting the users from being infected with Middle East respiratory syndrome and severe acute respiratory syndrome coronavirus (SARS-CoV), but the evidence for SARS-CoV-2 during daily work is limited. This study utilized a subset of healthcare workers' temporary use of a new brand respirator with frequent defects when caring for coronavirus disease 2019 (COVID-19) patients to assess the protective effect of regular respirators against SARS-CoV-2 infection. We retrospectively followed 463 participants wearing a regular respirator and 168 wearing the new brand respirator day-by-day when caring for COVID-19 patients until testing polymerase chain reaction positive for SARS-CoV-2 between 27th December 2020 and 14th January 2021. We observed seven and eight incident SARS-CoV-2-infected cases. This corresponded with daily infection rates of 0.2 and 0.5%, an incidence rate ratio of 0.4 [95% confidence interval (CI) 0.1; 1.0], and an incidence rate difference of 0.3% (95% CI -0.1; 0.8) when comparing a regular with the new brand respirator. We regard the new brand respirator a sham intervention, and this study thus provides further evidence for the protective effect of respirators when exposed to SARS-CoV-2 virus.

Sections du résumé

BACKGROUND
There is strong observational evidence that respirators are highly effective in protecting the users from being infected with Middle East respiratory syndrome and severe acute respiratory syndrome coronavirus (SARS-CoV), but the evidence for SARS-CoV-2 during daily work is limited. This study utilized a subset of healthcare workers' temporary use of a new brand respirator with frequent defects when caring for coronavirus disease 2019 (COVID-19) patients to assess the protective effect of regular respirators against SARS-CoV-2 infection.
METHODS
We retrospectively followed 463 participants wearing a regular respirator and 168 wearing the new brand respirator day-by-day when caring for COVID-19 patients until testing polymerase chain reaction positive for SARS-CoV-2 between 27th December 2020 and 14th January 2021.
RESULTS
We observed seven and eight incident SARS-CoV-2-infected cases. This corresponded with daily infection rates of 0.2 and 0.5%, an incidence rate ratio of 0.4 [95% confidence interval (CI) 0.1; 1.0], and an incidence rate difference of 0.3% (95% CI -0.1; 0.8) when comparing a regular with the new brand respirator.
DISCUSSION
We regard the new brand respirator a sham intervention, and this study thus provides further evidence for the protective effect of respirators when exposed to SARS-CoV-2 virus.

Identifiants

pubmed: 35488370
pii: 6576216
doi: 10.1093/annweh/wxac031
doi:

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

141-146

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

Auteurs

Henrik A Kolstad (HA)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.
Institute of Clinical Medicine, Aarhus University, DK-8200 Aarhus N, Denmark.

Morten Frydenberg (M)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Kent Jacob Nielsen (KJ)

Department of Occupational Medicine, Danish Ramazzini Centre, Goedstrup Hospital, DK-7400 Herning, Denmark.

Vivi Schlünssen (V)

Department of Public Health, Work, Environment and Health, Danish Ramazzini Centre, Aarhus University, DK-8000 Aarhus C, Denmark.

Karin Biering (K)

Department of Occupational Medicine, Danish Ramazzini Centre, Goedstrup Hospital, DK-7400 Herning, Denmark.

Mona Kjærsgaard (M)

Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Jesper Medom Vestergaard (JM)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Else Toft Würtz (ET)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Kirsten Pugdahl (K)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Anne Mette Lund Würtz (AML)

Department of Public Health, Work, Environment and Health, Danish Ramazzini Centre, Aarhus University, DK-8000 Aarhus C, Denmark.

Karoline Kærgaard Hansen (KK)

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Sanne Jespersen (S)

Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Marianne Kragh Thomsen (M)

Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Mette Marie Sørensen (MM)

Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Svend Ellermann-Eriksen (S)

Department of Clinical Microbiology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Jacob Dvinge Redder (J)

Business Intelligence, Central Denmark Region, DK-8200 Aarhus N, Denmark.

Merete Storgaard (M)

Department of Infectious Diseases, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH