Management of alcohol-related liver disease: the French Association for the Study of the Liver and the French Alcohol Society clinical guidelines.

alcohol alcohol-related liver disease guidelines

Journal

Liver international : official journal of the International Association for the Study of the Liver
ISSN: 1478-3231
Titre abrégé: Liver Int
Pays: United States
ID NLM: 101160857

Informations de publication

Date de publication:
06 2022
Historique:
revised: 14 02 2022
received: 12 11 2021
accepted: 16 02 2022
pubmed: 1 5 2022
medline: 11 6 2022
entrez: 30 4 2022
Statut: ppublish

Résumé

Excessive alcohol consumption is the leading cause of liver diseases in Western countries, especially in France. Alcohol-related liver disease (ARLD) is an extremely broad context and there remains much to accomplish in terms of identifying patients, improving prognosis and treatment, and standardising practices. The French Association for the Study of the Liver wished to organise guidelines together with the French Alcohol Society in order to summarise the best evidence available about several key clinical points in ARLD. These guidelines have been elaborated based on the level of evidence available in the literature and each recommendation has been analysed, discussed and voted by the panel of experts. They describe how patients with ARLD should be managed nowadays and discuss the main unsettled issues in the field.

Identifiants

pubmed: 35488390
doi: 10.1111/liv.15221
doi:

Substances chimiques

Ethanol 3K9958V90M

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1330-1343

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

© 2022 John Wiley & Sons A/S . Published by John Wiley & Sons Ltd.

Références

Toxicomanies Ofdded. 2018.
Anderson P, O'Donnell A, Kaner E, Llopis EJ, Manthey J, Rehm J. Impact of minimum unit pricing on alcohol purchases in Scotland and Wales: controlled interrupted time series analyses. Lancet Public Health. 2021;6(8):e557-e565.
Pimpin L, Cortez-Pinto H, Negro F, et al. Burden of liver disease in Europe: epidemiology and analysis of risk factors to identify prevention policies. J Hepatol. 2018;69(3):718-735.
Wagenaar AC, Tobler AL, Komro KA. Effects of alcohol tax and price policies on morbidity and mortality: a systematic review. Am J Public Health. 2010;100(11):2270-2278.
WHO. Global status report on noncommunicable diseases 2014. https://appswhoint/iris/bitstream/handle/10665/148114/9789241564854_engpdf.
GBD Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet. 2018;392(10152):1015-1035.
European Association for the Study of the liver. EASL clinical practice guidelines: management of alcohol-related liver disease. J Hepatol. 2018;69(1):154-181.
Société Française d'Alcoologie. Mésusage de l'alcool: dépistage, diagnostic et traitement. Alcool Addictol. 2015;37(1):5-84.
Aalto M, Alho H, Halme JT, Seppa K. AUDIT and its abbreviated versions in detecting heavy and binge drinking in a general population survey. Drug Alcohol Depend. 2009;103(1-2):25-29.
Gache P, Michaud P, Landry U, et al. The Alcohol use disorders identification test (AUDIT) as a screening tool for excessive drinking in primary care: reliability and validity of a French version. Alcohol Clin Exp Res. 2005;29(11):2001-2007.
Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the Alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful Alcohol consumption-II. Addiction. 1993;88(6):791-804.
Shields AL, Caruso JC. Reliability generalization of the alcohol use disorders identification test. Educ Psychol Meas. 2003;63(3):404-413.
Kuitunen-Paul S, Roerecke M. Alcohol use disorders identification test (AUDIT) and mortality risk: a systematic review and meta-analysis. J Epidemiol Community Health. 2018;72(9):856-863.
Patel AK, Balasanova AA. Unhealthy Alcohol use. Jama. 2021;326(2):196.
Alcohol Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence NICE Clinical Guidelines. 2011. Accessed March 29, 2022. https://www.nice.org.uk/guidance/cg115
Coulton S, Drummond C, James D, et al. Opportunistic screening for alcohol use disorders in primary care: comparative study. BMJ. 2006;332(7540):511-517.
Fagan KJ, Irvine KM, McWhinney BC, et al. Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterol. 2014;14:97.
Fujii H, Nishimoto N, Yamaguchi S, et al. The Alcohol use disorders identification test for consumption (AUDIT-C) is more useful than pre-existing laboratory tests for predicting hazardous drinking: a cross-sectional study. BMC Public Health. 2016;16:379.
Viel G, Boscolo-Berto R, Cecchetto G, Fais P, Nalesso A, Ferrara SD. Phosphatidylethanol in blood as a marker of chronic alcohol use: a systematic review and meta-analysis. Int J Mol Sci. 2012;13(11):14788-14812.
Wurst FM, Thon N, Yegles M, Schruck A, Preuss UW, Weinmann W. Ethanol metabolites: their role in the assessment of alcohol intake. Alcohol Clin Exp Res. 2015;39(11):2060-2072.
Kaner EF, Beyer F, Dickinson HO, et al. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev. 2007;(2):CD004148.
Kaner EF, Dickinson HO, Beyer F, et al. The effectiveness of brief alcohol interventions in primary care settings: a systematic review. Drug Alcohol Rev. 2009;28(3):301-323.
Bien TH, Miller WR, Tonigan JS. Brief interventions for alcohol problems: a review. Addiction. 1993;88(3):315-335.
Miller WR, Wilbourne PL. Mesa Grande: a methodological analysis of clinical trials of treatments for alcohol use disorders. Addiction. 2002;97(3):265-277.
Dawson DA. Defining risk drinking. Alcohol Res Health. 2011;34(2):144-156.
Wechsler H, Davenport A, Dowdall G, Moeykens B, Castillo S. Health and behavioral consequences of binge drinking in college. A national survey of students at 140 campuses. Jama. 1994;272(21):1672-1677.
Kuntsche E, Kuntsche S, Thrul J, Gmel G. Binge drinking: health impact, prevalence, correlates and interventions. Psychol Health. 2017;32(8):976-1017.
Aberg F, Helenius-Hietala J, Puukka P, Jula A. Binge drinking and the risk of liver events: a population-based cohort study. Liver Int. 2017;37(9):1373-1381.
Wood AM, Kaptoge S, Butterworth AS, et al. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. Lancet. 2018;391(10129):1513-1523.
Verges A, Ellingson JM, Schroder SA, Slutske WS, Sher KJ. Intensity of daily drinking and its relation to alcohol use disorders. Alcohol Clin Exp Res. 2018;42(9):1674-1683.
Kamper-Jorgensen M, Gronbaek M, Tolstrup J, Becker U. Alcohol and cirrhosis: dose-response or threshold effect? J Hepatol. 2004;41(1):25-30.
Askgaard G, Gronbaek M, Kjaer MS, Tjonneland A, Tolstrup JS. Alcohol drinking pattern and risk of alcoholic liver cirrhosis: a prospective cohort study. J Hepatol. 2015;62(5):1061-1067.
McCarty CA, Ebel BE, Garrison MM, DiGiuseppe DL, Christakis DA, Rivara FP. Continuity of binge and harmful drinking from late adolescence to early adulthood. Pediatrics. 2004;114(3):714-719.
Holahan CJ, Schutte KK, Brennan PL, Holahan CK, Moos RH. Episodic heavy drinking and 20-year total mortality among late-life moderate drinkers. Alcohol Clin Exp Res. 2014;38(5):1432-1438.
Santé Publique France. Avis d'experts relatif à l'évolution du discours public en matière de consommation d'alcool en France. 2017. Accessed March 29, 2022. https://www.santepubliquefrance.fr/les-actualites/2017/avis-d-experts-relatif-a-l-evolution-du-discours-public-en-matiere-de-consommation-d-alcool-en-france-organise-par-sante-publique-france-et-l-insti
Rumgay H, Shield K, Charvat H, et al. Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol. 2021;22(8):1071-1080.
Alcohol GBD, Drug UC. The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet Psychiatry. 2018;5(12):987-1012.
Kalinowski A, Humphreys K. Governmental standard drink definitions and low-risk alcohol consumption guidelines in 37 countries. Addiction. 2016;111(7):1293-1298.
Corrao G, Bagnardi V, Zambon A, La Vecchia C. A meta-analysis of alcohol consumption and the risk of 15 diseases. Prev Med. 2004;38(5):613-619.
Rehm J, Taylor B, Mohapatra S, et al. Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis. Drug Alcohol Rev. 2010;29(4):437-445.
Global Burden of Disease Liver Cancer Cancer, Akinyemiju T, Abera S, Ahmed M, Alam N, Alemayohu MA, et al. The burden of primary liver cancer and underlying etiologies from 1990 to 2015 at the global, regional, and National Level: results from the global burden of disease study 2015. JAMA Oncol. 2017;3(12):1683-91.
Bagnardi V, Rota M, Botteri E, et al. Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. Br J Cancer. 2015;112(3):580-593.
Trichopoulos D, Bamia C, Lagiou P, et al. Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study. J Natl Cancer Inst. 2011;103(22):1686-1695.
Donato F, Tagger A, Gelatti U, et al. Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women. Am J Epidemiol. 2002;155(4):323-331.
Hassan MM, Hwang LY, Hatten CJ, et al. Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology. 2002;36(5):1206-1213.
Heckley GA, Jarl J, Asamoah BO, Ulf GG. How the risk of liver cancer changes after alcohol cessation: a review and meta-analysis of the current literature. BMC Cancer. 2011;11:446.
Hezode C, Lonjon I, Roudot-Thoraval F, Pawlotsky JM, Zafrani ES, Dhumeaux D. Impact of moderate alcohol consumption on histological activity and fibrosis in patients with chronic hepatitis C, and specific influence of steatosis: a prospective study. Aliment Pharmacol Ther. 2003;17(8):1031-1037.
Cheung O, Sterling RK, Salvatori J, et al. Mild alcohol consumption is not associated with increased fibrosis in patients with chronic hepatitis C. J Clin Gastroenterol. 2011;45(1):76-82.
Pessione F, Ramond MJ, Peters L, et al. Five-year survival predictive factors in patients with excessive alcohol intake and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence. Liver Int. 2003;23(1):45-53.
Thun MJ, Peto R, Lopez AD, et al. Alcohol consumption and mortality among middle-aged and elderly U.S. adults. N Engl J Med. 1997;337(24):1705-1714.
Louvet A, Labreuche J, Artru F, et al. Main drivers of outcome differ between short term and long term in severe alcoholic hepatitis: a prospective study. Hepatology. 2017;66(5):1464-1473.
Shih WL, Chang HC, Liaw YF, et al. Influences of tobacco and alcohol use on hepatocellular carcinoma survival. Int J Cancer. 2012;131(11):2612-2621.
Addolorato G, Leggio L, Ferrulli A, et al. Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study. Lancet. 2007;370(9603):1915-1922.
Addolorato G, Mirijello A, Barrio P, Gual A. Treatment of alcohol use disorders in patients with alcoholic liver disease. J Hepatol. 2016;65(3):618-630.
Caputo F, Domenicali M, Bernardi M. Diagnosis and treatment of Alcohol use disorder in patients with end-stage alcoholic liver disease. Hepatology. 2019;70(1):410-417.
Fuster D, Samet JH. Alcohol use in patients with chronic liver disease. N Engl J Med. 2018;379(13):1251-1261.
Garcia ML, Blasco-Algora S, Fernandez-Rodriguez CM. Alcohol liver disease: a review of current therapeutic approaches to achieve long-term abstinence. World J Gastroenterol. 2015;21(28):8516-8526.
Leggio L, Lee MR. Treatment of Alcohol use disorder in patients with alcoholic liver disease. Am J Med. 2017;130(2):124-134.
Mirijello A, D'Angelo C, Ferrulli A, et al. Identification and management of alcohol withdrawal syndrome. Drugs. 2015;75(4):353-365.
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. ACG clinical guideline: alcoholic liver disease. Am J Gastroenterol. 2018;113(2):175-194.
Sonne J, Andreasen PB, Loft S, Dossing M, Andreasen F. Glucuronidation of oxazepam is not spared in patients with hepatic encephalopathy. Hepatology. 1990;11(6):951-956.
Cook CC, Hallwood PM, Thomson AD. B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol Alcohol. 1998;33(4):317-336.
Day E, Bentham P, Callaghan R, Kuruvilla T, George S. Thiamine for Wernicke-Korsakoff syndrome in people at risk from alcohol abuse. Cochrane Database Syst Rev. 2004;(1):CD004033.
Latt N, Dore G. Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. Intern Med J. 2014;44(9):911-915.
Martin PR, Singleton CK, Hiller-Sturmhofel S. The role of thiamine deficiency in alcoholic brain disease. Alcohol Res Health. 2003;27(2):134-142.
Kranzler HR, Soyka M. Diagnosis and pharmacotherapy of Alcohol use disorder: a review. JAMA. 2018;320(8):815-824.
Lackner C, Spindelboeck W, Haybaeck J, et al. Histological parameters and alcohol abstinence determine long-term prognosis in patients with alcoholic liver disease. J Hepatol. 2017;66(3):610-618.
Naveau S, Gaude G, Asnacios A, et al. Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Hepatology. 2009;49(1):97-105.
Thiele M, Madsen BS, Hansen JF, Detlefsen S, Antonsen S, Krag A. Accuracy of the enhanced liver fibrosis test vs FibroTest, elastography, and indirect markers in detection of advanced fibrosis in patients with alcoholic liver disease. Gastroenterology. 2018;154(5):1369-1379.
Voican CS, Louvet A, Trabut JB, et al. Transient elastography alone and in combination with FibroTest([R]) for the diagnosis of hepatic fibrosis in alcoholic liver disease. Liver Int. 2017;37(11):1697-1705.
Zhang D, Li P, Chen M, et al. Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease using acoustic radiation force impulse elastography. Abdom Imaging. 2015;40(4):723-729.
Nguyen-Khac E, Chatelain D, Tramier B, et al. Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Aliment Pharmacol Ther. 2008;28(10):1188-1198.
Cales P, Oberti F, Michalak S, et al. A novel panel of blood markers to assess the degree of liver fibrosis. Hepatology. 2005;42(6):1373-1381.
Patouraux S, Bonnafous S, Voican CS, et al. The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver disease. PLoS One. 2012;7(4):e35612.
Nguyen-Khac E, Thiele M, Voican C, et al. Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis. Lancet Gastroenterol Hepatol. 2018;3(9):614-625.
Pavlov CS, Casazza G, Nikolova D, et al. Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease. Cochrane Database Syst Rev. 2015;1:CD010542.
Trabut JB, Thepot V, Nalpas B, et al. Rapid decline of liver stiffness following alcohol withdrawal in heavy drinkers. Alcohol Clin Exp Res. 2012;36(8):1407-1411.
Gianni E, Forte P, Galli V, Razzolini G, Bardazzi G, Annese V. Prospective evaluation of liver stiffness using transient elastography in alcoholic patients following abstinence. Alcohol Alcohol. 2017;52(1):42-47.
Hsu C, Caussy C, Imajo K, et al. Magnetic resonance vs transient elastography analysis of patients with nonalcoholic fatty liver disease: a systematic review and pooled analysis of individual participants. Clin Gastroenterol Hepatol. 2019;17(4):630-7 e8.
Bates ME, Buckman JF, Nguyen TT. A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders. Neuropsychol Rev. 2013;23(1):27-47.
Houghton D, Hallsworth K, Thoma C, et al. Effects of exercise on liver fat and metabolism in Alcohol drinkers. Clin Gastroenterol Hepatol. 2017;15(10):1596-603 e3.
European Association for the Study of the Liver, European Association for the Study of Diabetes, European Association for the Study of Obesity. EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016;64(6):1388-1402.
Cowan J, Devine C. Food, eating, and weight concerns of men in recovery from substance addiction. Appetite. 2008;50(1):33-42.
Gottfredson NC, Sokol RL. Explaining excessive weight gain during early recovery from addiction. Subst Use Misuse. 2019;54(5):769-778.
Cowan JA, Devine CM. Diet and body composition outcomes of an environmental and educational intervention among men in treatment for substance addiction. J Nutr Educ Behav. 2013;45(2):154-158.
Harman DJ, Ryder SD, James MW, et al. Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography. BMJ Open. 2015;5(4):e007516.
Deleuran T, Gronbaek H, Vilstrup H, Jepsen P. Cirrhosis and mortality risks of biopsy-verified alcoholic pure steatosis and steatohepatitis: a nationwide registry-based study. Aliment Pharmacol Ther. 2012;35(11):1336-1342.
Teli MR, Day CP, Burt AD, Bennett MK, James OF. Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet. 1995;346(8981):987-990.
Harris R, Harman DJ, Card TR, Aithal GP, Guha IN. Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review. Lancet Gastroenterol Hepatol. 2017;2(4):288-297.
Poynard T, Lebray P, Ingiliz P, et al. Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest). BMC Gastroenterol. 2010;10:40.
Caballeria L, Pera G, Arteaga I, et al. High prevalence of liver fibrosis among European adults with unknown liver disease: a population-based study. Clin Gastroenterol Hepatol. 2018;16(7):1138-45 e5.
Fabrellas N, Alemany M, Urquizu M, et al. Using transient elastography to detect chronic liver diseases in a primary care nurse consultancy. Nurs Res. 2013;62(6):450-454.
Roulot D, Costes JL, Buyck JF, et al. Transient elastography as a screening tool for liver fibrosis and cirrhosis in a community-based population aged over 45 years. Gut. 2011;60(7):977-984.
Matthews K, MacGilchrist A, Coulter-Smith M, Jones J, Cetnarskyj R. A nurse-led FibroScan([R]) outreach clinic encourages socially deprived heavy drinkers to engage with liver services. J Clin Nurs. 2019;28(3-4):650-662.
Boursier J, de Ledinghen V, Leroy V, et al. A stepwise algorithm using an at-a-glance first-line test for the non-invasive diagnosis of advanced liver fibrosis and cirrhosis. J Hepatol. 2017;66(6):1158-1165.
Sheron N, Moore M, Ansett S, Parsons C, Bateman A. Developing a 'traffic light' test with potential for rational early diagnosis of liver fibrosis and cirrhosis in the community. Br J Gen Pract. 2012;62(602):e616-e624.
Kryger P, Schlichting P, Dietrichson O, Juhl E. The accuracy of the clinical diagnosis in acute hepatitis and alcoholic liver disease. Clinical versus morphological diagnosis. Scand J Gastroenterol. 1983;18(5):691-696.
Ramond MJ, Poynard T, Rueff B, et al. A randomized trial of prednisolone in patients with severe alcoholic hepatitis. N Engl J Med. 1992;326(8):507-512.
O'Shea RS, Dasarathy S, McCullough AJ, Practice guideline Committee of the American Association for the Study of Liver Diseases, Practice Parameters Committee of the American College of Gastroenterology. Alcoholic liver disease. Hepatology. 2010;51(1):307-328.
Crabb DW, Bataller R, Chalasani NP, et al. Standard definitions and common data elements for clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA alcoholic hepatitis consortia. Gastroenterology. 2016;150(4):785-790.
Bissonnette J, Altamirano J, Devue C, et al. A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis. Hepatology. 2017;66(2):555-563.
Carithers RL Jr, Herlong HF, Diehl AM, et al. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann Intern Med. 1989;110(9):685-690.
Maddrey WC, Boitnott JK, Bedine MS, Weber FL Jr, Mezey E, White RI Jr. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology. 1978;75(2):193-199.
Dunn W, Jamil LH, Brown LS, et al. MELD accurately predicts mortality in patients with alcoholic hepatitis. Hepatology. 2005;41(2):353-358.
Dominguez M, Rincon D, Abraldes JG, et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol. 2008;103(11):2747-2756.
Forrest EH, Evans CD, Stewart S, et al. Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Gut. 2005;54(8):1174-1179.
Degre D, Stauber RE, Englebert G, et al. Long-term outcomes in patients with decompensated alcohol-related liver disease, steatohepatitis and Maddrey's discriminant function <32. J Hepatol. 2020;72(4):636-642.
Mathurin P, Abdelnour M, Ramond MJ, et al. Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone. Hepatology. 2003;38(6):1363-1369.
Louvet A, Naveau S, Abdelnour M, et al. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology. 2007;45(6):1348-1354.
Garcia-Saenz-de-Sicilia M, Duvoor C, Altamirano J, et al. A Day-4 Lille model predicts response to corticosteroids and mortality in severe alcoholic hepatitis. Am J Gastroenterol. 2017;112(2):306-315.
Mathurin P, O'Grady J, Carithers RL, et al. Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data. Gut. 2011;60(2):255-260.
Louvet A, Wartel F, Castel H, et al. Infection in patients with severe alcoholic hepatitis treated with steroids: early response to therapy is the key factor. Gastroenterology. 2009;137(2):541-548.
Vergis N, Atkinson SR, Knapp S, et al. In patients with severe alcoholic hepatitis, prednisolone increases susceptibility to infection and infection-related mortality, and is associated with high circulating levels of bacterial DNA. Gastroenterology. 2017;152(5):1068-77 e4.
Gustot T, Maillart E, Bocci M, et al. Invasive aspergillosis in patients with severe alcoholic hepatitis. J Hepatol. 2014;60(2):267-274.
Louvet A, Labreuche J, Artru F, et al. Combining data from liver disease scoring systems better predicts outcomes of patients with alcoholic hepatitis. Gastroenterology. 2015;149(2):398-406 e8. quiz e16-7.
Louvet A, Thursz MR, Kim DJ, et al. Corticosteroids reduce risk of death within 28 days for patients with severe alcoholic hepatitis, compared with pentoxifylline or placebo-a meta-analysis of individual data from controlled trials. Gastroenterology. 2018;155(2):458-68 e8.
Thursz MR, Richardson P, Allison M, et al. Prednisolone or pentoxifylline for alcoholic hepatitis. N Engl J Med. 2015;372(17):1619-1628.
Nguyen-Khac E, Thevenot T, Piquet MA, et al. Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. N Engl J Med. 2011;365(19):1781-1789.
Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology. 2000;119(6):1637-1648.
Mathurin P, Louvet A, Duhamel A, et al. Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA. 2013;310(10):1033-1041.
Mathurin P, Moreno C, Samuel D, et al. Early liver transplantation for severe alcoholic hepatitis. N Engl J Med. 2011;365(19):1790-1800.
Im GY, Kim-Schluger L, Shenoy A, et al. Early liver transplantation for severe alcoholic hepatitis in the United States-a single-center experience. Am J Transplant. 2016;16(3):841-849.
Lee BP, Mehta N, Platt L, et al. Outcomes of early liver transplantation for patients with severe alcoholic hepatitis. Gastroenterology. 2018;155(2):422-30 e1.
Singal AK, Bashar H, Anand BS, Jampana SC, Singal V, Kuo YF. Outcomes after liver transplantation for alcoholic hepatitis are similar to alcoholic cirrhosis: exploratory analysis from the UNOS database. Hepatology. 2012;55(5):1398-1405.
Weeks SR, Sun Z, McCaul ME, et al. Liver transplantation for severe alcoholic hepatitis, updated lessons from the World's largest series. J Am Coll Surg. 2018;226(4):549-557.

Auteurs

Alexandre Louvet (A)

Service des Maladies de l'Appareil digestif, Hôpital Huriez, CHU, Lille, France.

Jean-Baptiste Trabut (JB)

Groupe Hospitalier Cochin Saint-Vincent de Paul, Unité d'Hépatologie et d'Addictologie, Paris, France.

Christophe Moreno (C)

Hepato-Gastroenterology, ULB Erasme, Brussels, Belgium.

Romain Moirand (R)

Inserm, UMR 991, "Foie, Métabolismes et Cancer", Rennes, France.
Université de Rennes 1, Rennes, France.

Henri-Jean Aubin (HJ)

Service d'Addictologie, Hôpital Paul-Brousse, Villejuif, France.

Line Carolle Ntandja Wandji (LC)

Service des Maladies de l'Appareil digestif, Hôpital Huriez, CHU, Lille, France.

Mikail Nourredine (M)

Service d'Addictologie, Hospices Civils de Lyon, Lyon, France.

Massih Ningarhari (M)

Service des Maladies de l'Appareil digestif, Hôpital Huriez, CHU, Lille, France.

Nathalie Ganne-Carrié (N)

Service d'Hépatologie, Hôpital Avicenne, Bobigny, France.

Georges-Philippe Pageaux (GP)

Service d'Hépato-Gastroentérologie, CHU Saint-Eloi, Montpellier, France.

François Bailly (F)

Service d'Hépato-Gastroentérologie, Hospices Civils de Lyon, Lyon, France.

Jérôme Boursier (J)

Service d'Hépato-Gastroentérologie, CHU, Angers, France.

Jean-Bernard Daeppen (JB)

Médecine des Addictions, CHUV, Lausanne, Switzerland.

Amandine Luquiens (A)

Service d'Addictologie, CHU, Nîmes, France.

Eric Nguyen-Khac (E)

Service d'Hépato-Gastroentérologie, CHU, Amiens, France.

Rodolphe Anty (R)

Service d'Hépato-Gastroentérologie, CHU de l'Archet 2, Nice, France.

Thomas Orban (T)

Société Scientifique de Médecine Générale, Brussels, Belgium.

Hélène Donnadieu-Rigole (H)

Service d'Addictologie, CHU Saint-Eloi, Montpellier, France.

Ariane Mallat (A)

Service d'Hépatologie, Hopital Henri-Mondor, Créteil, France.

Christophe Bureau (C)

Service d'Hépato-Gastroentérologie, CHU, Toulouse, France.

Emile-Alexandre Pariente (EA)

Service d'Hépato-Gastroentérologie, Centre Hospitalier, Pau, France.

Thierry Paupard (T)

Service d'Hépato-Gastroentérologie, Centre Hospitalier, Dunkerque, France.

Amine Benyamina (A)

Service d'Addictologie, Hôpital Paul-Brousse, Villejuif, France.

Pascal Perney (P)

Service d'Addictologie, CHU, Nîmes, France.

Philippe Mathurin (P)

Service des Maladies de l'Appareil digestif, Hôpital Huriez, CHU, Lille, France.

Benjamin Rolland (B)

Service Universitaire d'Addictologie de Lyon (SUAL), CH Le Vinatier, Université de Lyon, UCBL, Lyon, France.

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