Hyperventilation-induced focal seizures in adults: think autoimmune encephalitis.


Journal

Annals of clinical and translational neurology
ISSN: 2328-9503
Titre abrégé: Ann Clin Transl Neurol
Pays: United States
ID NLM: 101623278

Informations de publication

Date de publication:
06 2022
Historique:
received: 19 04 2022
accepted: 20 04 2022
pubmed: 1 5 2022
medline: 15 6 2022
entrez: 30 4 2022
Statut: ppublish

Résumé

Case reports have described rare patients with autoimmune encephalitis in whom focal seizures could be reliably provoked by hyperventilation. With the hypothesis that this phenomenon may have diagnostic significance, all cases of hyperventilation-induced focal seizures identified during ~10,000 consecutive routine electroencephalography (EEG) studies were reviewed, and corresponding diagnoses established. Seven EEG recordings, in six patients, contained focal hyperventilation-induced seizures, each of temporal lobe onset. All patients were diagnosed with autoimmune encephalitis, in two cases after EEG; five had voltage-gated potassium channel complex autoantibodies. Although rare, a hyperventilation-induced focal seizure during EEG in an adult should raise concern for autoimmune encephalitis.

Identifiants

pubmed: 35488768
doi: 10.1002/acn3.51566
pmc: PMC9186130
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

877-881

Informations de copyright

© 2022 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association.

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Auteurs

Richard A Wennberg (RA)

Clinical Neurophysiology Laboratory, Krembil Brain Institute, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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Classifications MeSH