The expression pattern of membranous TNF-α is distinct from its intracellular form in breast cancer-draining lymph nodes.

B-Lymphocytes Breast Neoplasms Female Humans Lymph Nodes Tumor Necrosis Factor-alpha
Breast cancer Lymphocyte Membranous TNF-α TNF-α Tumor-draining lymph node

Journal

Clinical immunology (Orlando, Fla.)
ISSN: 1521-7035
Titre abrégé: Clin Immunol
Pays: United States
ID NLM: 100883537

Informations de publication

Date de publication:
05 2022
Historique:
received: 01 09 2021
revised: 02 03 2022
accepted: 23 04 2022
pubmed: 1 5 2022
medline: 18 5 2022
entrez: 30 4 2022
Statut: ppublish

Résumé

Tumor necrosis factor-alpha (TNF-α) is mostly known as a soluble cytokine. This study, however, focused on its membranous form whose significance is rarely investigated in antitumor immunity. Herein, we assessed the expression of both membranous and intracellular forms of TNF-α (m/icTNF-α) in the lymphocytes derived from breast cancer-draining lymph nodes. CD4

Identifiants

DOI: 10.1016/j.clim.2022.109026 PMID: 35489644
pubmed: 35489644
pii: S1521-6616(22)00107-3
doi: 10.1016/j.clim.2022.109026
pii:
doi:

Substances chimiques

Tumor Necrosis Factor-alpha 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109026

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Atri Ghods (A)

Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Fereshteh Mehdipour (F)

Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: mehdipourf@sums.ac.ir.

Reza Rasolmali (R)

Department of Pathology, Shiraz Central Hospital, Shiraz, Iran.

Abdol-Rasoul Talei (AR)

Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Abbas Ghaderi (A)

Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: ghaderia@sums.ac.ir.

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Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes B › The expression pattern of membranous TNF-α is...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › The expression pattern of membranous TNF-α is...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The expression pattern of membranous TNF-α is...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Noeuds lymphatiques › The expression pattern of membranous TNF-α is...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de nécrose tumorale › Facteur de nécrose tumorale alpha › The expression pattern of membranous TNF-α is...