A chitosan gold nanoparticles molecularly imprinted polymer based ciprofloxacin sensor.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
30 Mar 2020
Historique:
received: 26 02 2020
accepted: 10 03 2020
entrez: 2 5 2022
pubmed: 31 3 2020
medline: 31 3 2020
Statut: epublish

Résumé

In this work, we present a novel study on the development of an electrochemical biomimetic sensor to detect the ciprofloxacin (CIP) antibiotic. A chitosan gold nanoparticles decorated molecularly imprinted polymer (Ch-AuMIP) was used to modify the glassy carbon electrode (GCE) for preparation of the sensor. The Ch-AuMIP was characterized to understand various properties like chemical composition, morphology, roughness, and conduction using Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), atomic force microscopy (AFM) and cyclic voltammetry (CV) respectively. Several experimental conditions affecting the Ch-AuMIP/GCE sensor such as the CIP removal agent, the extraction time, the volume of Ch-AuMIP drop-cast onto GCE and the rebinding time were studied and optimized. The Ch-AuMIP sensor sensitivity was studied in the concentration range of 1-100 μmol L

Identifiants

pubmed: 35492136
doi: 10.1039/d0ra01838d
pii: d0ra01838d
pmc: PMC9051084
doi:

Types de publication

Journal Article

Langues

eng

Pagination

12823-12832

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

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Auteurs

Sandeep G Surya (SG)

Sensors Lab, Advanced Membranes and Porous Materials Center, Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST) Saudi Arabia.

Shahjadi Khatoon (S)

Department of Chemistry, Chaudhary Charan Singh University Meerut 250004 India.

Abdellatif Ait Lahcen (A)

Sensors Lab, Advanced Membranes and Porous Materials Center, Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST) Saudi Arabia.

An T H Nguyen (ATH)

Sensors Lab, Advanced Membranes and Porous Materials Center, Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST) Saudi Arabia.

Boris B Dzantiev (BB)

A. N. Bach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences Moscow Russia khaled.salama@kaust.edu,sa naz1012@gmail.com.

Nazia Tarannum (N)

Department of Chemistry, Chaudhary Charan Singh University Meerut 250004 India.

Khaled N Salama (KN)

Sensors Lab, Advanced Membranes and Porous Materials Center, Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST) Saudi Arabia.

Classifications MeSH