A Novel Method for Training the Interdiction of Restricted and Hazardous Biological Materials by Detection Dogs.

bio-agent detection bio-detection bio-threat detection canine detection dog viral detection

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2022
Historique:
received: 03 01 2022
accepted: 21 03 2022
entrez: 2 5 2022
pubmed: 3 5 2022
medline: 3 5 2022
Statut: epublish

Résumé

The interdiction of restricted and hazardous biological agents presents challenges for any detection method due to the inherent complexity of sample type and accessibility. Detection capabilities for this category of agents are limited and restricted in their mobility, adaptability and efficiency. The potential for identifying biological agents through a volatile organic compound (VOC) signature presents an opportunity to use detection dogs in a real-time mobile capacity for surveillance and screening strategies. However, the safe handling and access to the materials needed for training detection dogs on restricted or hazardous biological agents prevents its broader application in this field. This study evaluated the use of a polymer-based training aid in a viral detection model using bovine viral diarrhea virus mimicking biosafety level 3+ agent conditions. After the biological agent-based odor was absorbed into the polymer, the aid was rendered safe for handling through a rigorous sterilization process. The viral culture-based training aid was then used to train a cohort of detection dogs (

Identifiants

pubmed: 35492309
doi: 10.3389/fmed.2022.847620
pmc: PMC9042221
doi:

Types de publication

Journal Article

Langues

eng

Pagination

847620

Informations de copyright

Copyright © 2022 Singletary, Krichbaum, Passler, Lazarowski, Fischer, Silvis, Waggoner, Walz and Angle.

Déclaration de conflit d'intérêts

CA, TP, TF, and LW are represented on the patent, pending (TRAINING AID Patent Pending 2020 338518: 47-19 US). The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Melissa Singletary (M)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Sarah Krichbaum (S)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Thomas Passler (T)

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Lucia Lazarowski (L)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Terrence Fischer (T)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Scott Silvis (S)

Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

L Paul Waggoner (LP)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Paul Walz (P)

Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Craig Angle (C)

Canine Performance Sciences Program, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Classifications MeSH