Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
22 Jan 2020
Historique:
received: 25 08 2019
accepted: 09 12 2019
entrez: 2 5 2022
pubmed: 23 1 2020
medline: 23 1 2020
Statut: epublish

Résumé

Herein, we focused on developing the feasibility of nano-enabled local anaesthetic (LA) delivery to anaesthetise the full thickness of eyelid skin. For this purpose a temperature-responsive hydrogel poly(

Identifiants

pubmed: 35492666
doi: 10.1039/c9ra06712d
pii: c9ra06712d
pmc: PMC9048424
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3926-3930

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

Références

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Int J Biol Macromol. 2019 Mar 15;125:478-484
pubmed: 30529556
Br J Ophthalmol. 2016 Jun;100(6):871-6
pubmed: 26994111
Carbohydr Polym. 2016 Nov 5;152:687-698
pubmed: 27516320
Arch Dermatol. 1999 Jul;135(7):855-6
pubmed: 10411170
Colloids Surf B Biointerfaces. 2013 Feb 1;102:891-7
pubmed: 23107966
Plast Reconstr Surg Glob Open. 2014 Jun 06;2(5):e143
pubmed: 25289336

Auteurs

Bengi Ozkahraman (B)

Hitit University, Faculty of Engineering, Polymer Engineering Department 19030 Corum Turkey.
Biophysics Group, Department of Physics and Astronomy, University College London Gower Street London WC1E 6BT UK ntk.thanh@ucl.ac.uk.

Krisztina Emeriewen (K)

Moorfields Eye Hospital NHS Foundation Trust London EC1V 2PD UK.

George M Saleh (GM)

Moorfields Eye Hospital NHS Foundation Trust London EC1V 2PD UK.
The National Insitute for Health Research Biomedical Research Centre at Moorfields Eye Hospital, UCL Institute of Opthalmology 11-43 Bath St London EC1V 9EL UK.

Nguyen Thi Kim Thanh (NTK)

Biophysics Group, Department of Physics and Astronomy, University College London Gower Street London WC1E 6BT UK ntk.thanh@ucl.ac.uk.
UCL Healthcare Biomagnetic and Nanomaterials Laboratories, University College London 21 Albemarle Street London W1S 4BS UK.

Classifications MeSH