Dolutegravir Resistance in Malawi's National HIV Treatment Program.

Africa HIV Malawi antiretroviral therapy dolutegravir resistance

Journal

Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045

Informations de publication

Date de publication:
May 2022
Historique:
received: 21 12 2021
accepted: 04 04 2022
entrez: 2 5 2022
pubmed: 3 5 2022
medline: 3 5 2022
Statut: epublish

Résumé

Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020-September 2021). Of 6462 eligible clients, 33 samples were submitted to South Africa, 27 were sequenced successfully, and 8 (30%) had dolutegravir HIVDR. Malawi urgently requires adequate HIVDR testing capacity.

Identifiants

pubmed: 35493118
doi: 10.1093/ofid/ofac148
pii: ofac148
pmc: PMC9045949
doi:

Types de publication

Journal Article

Langues

eng

Pagination

ofac148

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

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Auteurs

Joep J van Oosterhout (JJ)

Partners in Hope, Lilongwe, Malawi.
Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

Chifundo Chipungu (C)

Partners in Hope, Lilongwe, Malawi.

Lyse Nkhoma (L)

The Lighthouse Trust, Lilongwe, Malawi.

Hope Kanise (H)

Partners in Hope, Lilongwe, Malawi.

Mina C Hosseinipour (MC)

University of North Carolina Project Malawi, Lilongwe, Malawi.

Jean Babtiste Sagno (JB)

DREAM, Communion of St. Egidio, Blantyre, Malawi.

Katherine Simon (K)

Baylor College of Medicine Children's Foundation-Malawi, Lilongwe, Malawi.
Baylor International Pediatric AIDS Initiative, Houston, Texas, USA.

Carrie Cox (C)

Baylor College of Medicine Children's Foundation-Malawi, Lilongwe, Malawi.
Baylor International Pediatric AIDS Initiative, Houston, Texas, USA.

Risa Hoffman (R)

Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

Kim Steegen (K)

Department of Haematology & Molecular Medicine, National Health Laboratory Service, Johannesburg, South Africa.
Department of Haematology & Molecular Medicine, University of the Witwatersrand, Johannesburg, South Africa.

Bilaal W Matola (BW)

Department of Public Health and Family Medicine, Kamuzu University of Health Sciences, Lilongwe, Malawi.

Sam Phiri (S)

Partners in Hope, Lilongwe, Malawi.
Department of Public Health and Family Medicine, Kamuzu University of Health Sciences, Lilongwe, Malawi.

Andreas Jahn (A)

Department of HIV-AIDS, Ministry of Health, Lilongwe, Malawi.

Rose Nyirenda (R)

Department of HIV-AIDS, Ministry of Health, Lilongwe, Malawi.

Tom Heller (T)

The Lighthouse Trust, Lilongwe, Malawi.

Classifications MeSH