Simulated spatial radiation impacts learning and memory ability with alterations of neuromorphology and gut microbiota in mice.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
21 Apr 2020
Historique:
received: 03 02 2020
accepted: 01 04 2020
entrez: 2 5 2022
pubmed: 23 4 2020
medline: 23 4 2020
Statut: epublish

Résumé

Complex space environments, including microgravity and radiation, affect the body's central nervous system, endocrine system, circulatory system, and reproductive system. Radiation-induced aberration in the neuronal integrity and cognitive functions are particularly well known. Moreover, ionizing radiation is a likely contributor to alterations in the microbiome. However, there is a lacuna between radiation-induced memory impairment and gut microbiota. The present study was aimed at investigating the effects of simulated space-type radiation on learning and memory ability and gut microbiota in mice. Adult mice were irradiated by

Identifiants

pubmed: 35493686
doi: 10.1039/d0ra01017k
pii: d0ra01017k
pmc: PMC9052872
doi:

Types de publication

Journal Article

Langues

eng

Pagination

16196-16208

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Chen Song (C)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Xin Gao (X)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Wei Song (W)

College of Food Science and Technology, Northwest University Xi'an 710069 China.
Laboratory of Nutritional and Healthy Food-Individuation Manufacturing Engineering Xi'an 710069 Shanxi China.

Deyong Zeng (D)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Shan Shan (S)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Yishu Yin (Y)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Yongzhi Li (Y)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
China Astronaut Research and Training Centre Beijing China.

Denis Baranenko (D)

Biotechnologies of the Third Millennium, ITMO University Saint-Petersburg Russia.

Weihong Lu (W)

Institute of Extreme Environment Nutrition and Protection, Harbin Institute of Technology Harbin China lwh@hit.edu.cn.
National Local Joint Laboratory of Extreme Environmental Nutritional Molecule Synthesis Transformation and Separation Harbin China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Classifications MeSH