First-in-Human Computational Preprocedural Planning of Left Main Interventions Using a New Everolimus-Eluting Stent.
3D, 3-dimensional
CAD, coronary artery disease
CFD, computational fluid dynamics
HD IVUS, high-definition intravascular ultrasound
LAD, left anterior descending
LCx, left circumflex
LM, left main
PCI, percutaneous coronary intervention
computational simulations
coronary artery disease
imaging
left main
percutaneous coronary interventions
stents
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
16 Mar 2022
16 Mar 2022
Historique:
received:
24
06
2021
revised:
13
01
2022
accepted:
03
02
2022
entrez:
2
5
2022
pubmed:
3
5
2022
medline:
3
5
2022
Statut:
epublish
Résumé
Left main coronary artery stenting requires rigorous planning and optimal execution. This case series presents a new approach to left main stenting guided by preprocedural patient-specific computational simulations. Three patients with significant left main artery disease underwent simulation-guided intervention using a novel stent scaffold purpose-built for large coronary arteries. (
Identifiants
pubmed: 35495558
doi: 10.1016/j.jaccas.2022.02.001
pii: S2666-0849(22)00108-5
pmc: PMC9040115
doi:
Types de publication
Case Reports
Langues
eng
Pagination
325-335Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL144690
Pays : United States
Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
This work was funded by the National Institutes of Health grant (R01 HL144690) and by the Dr Vincent Miscia Cardiovascular Research Fund, University of Nebraska Medical Center. Dr Chatzizisis has received speaker honoraria, advisory board fees, and research grant support from Boston Scientific; has received advisory board fees and research grant support from Medtronic; has a holding U.S. patent No. 11,026,749; has an international patent pending (PCT/US2020/057304) for the invention titled “Computational simulation platform for the planning of interventional procedures”; and is a cofounder of ComKardia. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
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