The Cell as Matter: Connecting Molecular Biology to Cellular Functions.
Journal
Matter
ISSN: 2590-2385
Titre abrégé: Matter
Pays: United States
ID NLM: 101749591
Informations de publication
Date de publication:
02 Jun 2021
02 Jun 2021
Historique:
entrez:
2
5
2022
pubmed:
3
5
2022
medline:
3
5
2022
Statut:
ppublish
Résumé
Viewing cell as matter to understand the intracellular biomolecular processes and multicellular tissue behavior represents an emerging research area at the interface of physics and biology. Cellular material displays various physical and mechanical properties, which can strongly affect both intracellular and multicellular biological events. This review provides a summary of how cells, as matter, connect molecular biology to cellular and multicellular scale functions. As an impact in molecular biology, we review recent progresses in utilizing cellular material properties to direct cell fate decisions in the communities of immune cells, neurons, stem cells, and cancer cells. Finally, we provide an outlook on how to integrate cellular material properties in developing biophysical methods for engineered living systems, regenerative medicine, and disease treatments.
Identifiants
pubmed: 35495565
doi: 10.1016/j.matt.2021.03.013
pmc: PMC9053450
mid: NIHMS1747884
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1863-1891Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM140108
Pays : United States
Déclaration de conflit d'intérêts
DECLARATION OF INTERESTS: The authors declare no competing interests.
Références
Science. 2016 Apr 15;352(6283):353-8
pubmed: 27013428
Curr Opin Biotechnol. 2020 Dec;66:236-245
pubmed: 33007634
J Immunol. 2013 May 1;190(9):4661-75
pubmed: 23554309
Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17588-93
pubmed: 25422455
J Cell Sci. 2018 Jul 4;131(13):
pubmed: 29777038
Cancer Cell. 2005 Sep;8(3):175-6
pubmed: 16169461
Nat Cell Biol. 2019 Mar;21(3):348-358
pubmed: 30742093
Nature. 2018 Sep;561(7723):401-405
pubmed: 30185907
Brain Behav Immun. 2014 Mar;37:1-14
pubmed: 24412599
Annu Rev Biophys. 2011;40:361-78
pubmed: 21391812
Nat Mater. 2010 Jan;9(1):82-8
pubmed: 19838182
Biophys J. 2000 Apr;78(4):1736-47
pubmed: 10733956
Nat Mater. 2010 Jun;9(6):518-26
pubmed: 20418863
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2241-6
pubmed: 24469820
Curr Opin Cell Biol. 2019 Feb;56:115-121
pubmed: 30554028
J Cell Biol. 2019 Aug 5;218(8):2545-2563
pubmed: 31239284
Nat Rev Mol Cell Biol. 2017 Dec;18(12):717-727
pubmed: 29044247
Nat Commun. 2017 Dec 6;8(1):1962
pubmed: 29213086
Nat Mater. 2013 Mar;12(3):253-61
pubmed: 23291707
Nat Cell Biol. 2021 Jul;23(7):745-757
pubmed: 34155382
Phys Rev Lett. 2001 Oct 1;87(14):148102
pubmed: 11580676
J R Soc Interface. 2010 Jun 6;7 Suppl 3:S321-30
pubmed: 20356876
Sci Transl Med. 2020 Jul 22;12(553):
pubmed: 32718990
Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9529-9534
pubmed: 28827333
Sci Adv. 2017 Jun 14;3(6):e1602536
pubmed: 28630905
Cell. 2018 Nov 29;175(6):1467-1480.e13
pubmed: 30500534
Cell. 2016 May 19;165(5):1160-1170
pubmed: 27203112
Proc Natl Acad Sci U S A. 2019 May 7;116(19):9245-9250
pubmed: 31019088
Nat Rev Mol Cell Biol. 2017 Dec;18(12):728-742
pubmed: 29115301
Nat Mater. 2019 Nov;18(11):1252-1263
pubmed: 31332337
J Comp Neurol. 2013 Apr 1;521(5):1184-201
pubmed: 22987820
Cancer Res. 2011 Aug 1;71(15):5075-80
pubmed: 21642375
PLoS One. 2012;7(5):e37178
pubmed: 22615930
Dev Cell. 2019 Mar 11;48(5):596-598
pubmed: 30861373
Development. 2017 Dec 1;144(23):4313-4321
pubmed: 29183942
Cell. 2020 May 14;181(4):800-817.e22
pubmed: 32302590
Science. 2013 Jun 28;340(6140):1587-90
pubmed: 23686338
Cell. 2014 Jul 3;158(1):143-156
pubmed: 24995985
Cell. 2017 Nov 30;171(6):1397-1410.e14
pubmed: 29107331
Cell. 2018 Nov 29;175(6):1481-1491.e13
pubmed: 30500535
Nat Cell Biol. 2014 Apr;16(4):376-81
pubmed: 24609268
Cancer Cell. 2018 Mar 12;33(3):480-494.e7
pubmed: 29533786
Biophys J. 2015 May 5;108(9):2181-90
pubmed: 25954876
Genes Dev. 2006 Feb 15;20(4):486-500
pubmed: 16481476
Biophys J. 2008 Dec 15;95(12):6052-9
pubmed: 18805929
Cell Stem Cell. 2021 Feb 4;28(2):209-216.e4
pubmed: 33207217
Nat Methods. 2018 Jul;15(7):491-498
pubmed: 29915189
Nature. 2003 Jan 30;421(6922):499-506
pubmed: 12556884
Nat Mater. 2015 Oct;14(10):1040-8
pubmed: 26237129
Sci Adv. 2020 Apr 01;6(14):eaay9095
pubmed: 32270037
Nat Immunol. 2019 Nov;20(11):1422-1424
pubmed: 31595058
Cell. 2013 May 23;153(5):948-62
pubmed: 23706734
Biophys J. 2017 Jun 6;112(11):2271-2279
pubmed: 28591600
Nat Commun. 2020 Sep 29;11(1):4902
pubmed: 32994402
Nature. 2007 May 31;447(7144):592-5
pubmed: 17538621
Cancer Res. 2021 Jan 15;81(2):476-488
pubmed: 33168645
Proc Natl Acad Sci U S A. 2015 May 26;112(21):6619-24
pubmed: 25918384
Curr Opin Cell Biol. 2015 Feb;32:1-6
pubmed: 25290386
Nat Rev Immunol. 2017 Oct;17(10):621-634
pubmed: 28690317
Nature. 2005 Jul 7;436(7047):123-7
pubmed: 16001073
Nat Rev Mol Cell Biol. 2019 Feb;20(2):69-84
pubmed: 30459476
Nat Phys. 2019 Jan;15(1):79-88
pubmed: 31537984
Nat Mater. 2006 Aug;5(8):636-40
pubmed: 16845421
J Biomech Eng. 2017 Feb 1;139(2):
pubmed: 27918797
Mol Biol Cell. 2016 Nov 1;27(21):3210-3213
pubmed: 27799497
J Cell Sci. 2016 Sep 1;129(17):3219-29
pubmed: 27530973
Nat Mater. 2019 Apr;18(4):397-405
pubmed: 30778227
Dev Cell. 2019 Jun 17;49(6):920-935.e5
pubmed: 31105008
Glia. 2019 Jul;67(7):1229-1239
pubmed: 30734358
Dev Cell. 2021 May 3;56(9):1313-1325.e7
pubmed: 33891898
Nat Mater. 2020 Apr;19(4):464-473
pubmed: 31844279
Nat Mater. 2014 Jun;13(6):645-52
pubmed: 24633344
Elife. 2016 Nov 30;5:
pubmed: 27901466
Cell Syst. 2018 Feb 28;6(2):192-205.e3
pubmed: 29361465
Nat Biomed Eng. 2019 Dec;3(12):1009-1019
pubmed: 31285581
Elife. 2014 Oct 15;3:e03695
pubmed: 25318069
Sci Adv. 2020 Jan 22;6(4):eaax5611
pubmed: 32010780
Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4409-18
pubmed: 25298531
Nat Commun. 2017 May 15;8:15321
pubmed: 28504269
Front Cell Neurosci. 2018 Feb 21;12:25
pubmed: 29515372
Nat Nanotechnol. 2013 Aug;8(8):602-8
pubmed: 23851358
Adv Immunol. 2014;123:69-100
pubmed: 24840948
Front Cell Neurosci. 2017 Aug 08;11:235
pubmed: 28848398
Nature. 2019 Sep;573(7772):130-134
pubmed: 31413369
Nat Commun. 2019 Apr 12;10(1):1695
pubmed: 30979898
Trends Cancer. 2018 Apr;4(4):320-331
pubmed: 29606315
Cell. 2014 Jul 31;158(3):633-46
pubmed: 25083873
Nat Immunol. 2005 Jan;6(1):80-9
pubmed: 15558067
Methods Enzymol. 2016;568:389-426
pubmed: 26795478
Nat Commun. 2020 Jul 10;11(1):3416
pubmed: 32651372
Cell. 2018 Jul 12;174(2):338-349.e20
pubmed: 29937223
Annu Rev Biomed Eng. 2000;2:189-226
pubmed: 11701511
Biophys J. 2013 Oct 1;105(7):1562-8
pubmed: 24094397
Math Biosci. 2014 Feb;248:140-5
pubmed: 24418008
Trends Biochem Sci. 2001 Oct;26(10):597-604
pubmed: 11590012
J Cell Biol. 2019 Dec 2;218(12):4079-4092
pubmed: 31676718
Nature. 2012 Sep 6;489(7414):57-74
pubmed: 22955616
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15619-24
pubmed: 17893336
Nat Rev Mater. 2020;5(11):847-860
pubmed: 33078077
Ann Biomed Eng. 2016 Jul;44(7):2123-31
pubmed: 26581348
J Cell Sci. 2017 Jul 15;130(14):2243-2250
pubmed: 28646093
Nat Med. 2014 Apr;20(4):360-7
pubmed: 24633304
Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10259-10264
pubmed: 16793927
Biomaterials. 2015 May;49:68-76
pubmed: 25725556
Curr Biol. 2017 Jan 23;27(2):210-223
pubmed: 27989676
Cell. 2006 Aug 25;126(4):677-89
pubmed: 16923388
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16148-53
pubmed: 25349416
Cell Stem Cell. 2021 Jan 7;28(1):170-172
pubmed: 33417868
Nat Cell Biol. 2018 Mar;20(3):262-271
pubmed: 29403039
Circ Res. 2008 Jul 3;103(1):16-23
pubmed: 18596264
Science. 2016 Apr 15;352(6283):359-62
pubmed: 27013426
PLoS One. 2012;7(2):e32572
pubmed: 22389710
Nat Immunol. 2016 Jul;17(7):870-7
pubmed: 27183103
Nat Commun. 2020 Dec 1;11(1):6148
pubmed: 33262337
Nat Rev Immunol. 2017 Nov;17(11):679-690
pubmed: 28757604
Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18507-12
pubmed: 24167274
J Biol Chem. 2021 Jan-Jun;296:100044
pubmed: 33168632
Dev Cell. 2020 Mar 9;52(5):563-573.e3
pubmed: 32032547
Annu Rev Biophys. 2010;39:207-26
pubmed: 20192775
Nat Mater. 2016 Aug;15(8):856-62
pubmed: 27043781
Nat Commun. 2020 Jan 7;11(1):20
pubmed: 31911639
Langmuir. 2006 May 23;22(11):5095-9
pubmed: 16700599
Nature. 2010 Jul 8;466(7303):192-3
pubmed: 20613830
Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3165-70
pubmed: 17360623
Nature. 2018 Nov;563(7730):203-208
pubmed: 30401836
Biomaterials. 2019 Mar;197:60-71
pubmed: 30641265
Curr Biol. 2013 Dec 16;23(24):R1113-21
pubmed: 24355792
Cell. 2019 Oct 31;179(4):937-952.e18
pubmed: 31675500
Nat Mater. 2014 Oct;13(10):970-8
pubmed: 24930031
Nat Phys. 2020 Jan;16(1):101-108
pubmed: 32905405
J Cell Biol. 2017 Jan 2;216(1):217-230
pubmed: 27923880
Trends Cell Biol. 2017 Apr;27(4):241-254
pubmed: 27986534
Nat Commun. 2019 Jul 29;10(1):3362
pubmed: 31358743
Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19632-7
pubmed: 23150585
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8618-E8627
pubmed: 28973866
Nature. 2001 May 24;411(6836):489-94
pubmed: 11373683
Nature. 2010 Jul 8;466(7303):263-6
pubmed: 20613844
Small. 2020 Sep;16(37):e2003656
pubmed: 32790058
Nat Methods. 2011 Feb;8(2):123-7
pubmed: 21278722
J Neuroinflammation. 2014 Jan 21;11:12
pubmed: 24447857
Cell Stem Cell. 2019 Nov 7;25(5):654-665.e4
pubmed: 31495781
Nat Rev Genet. 2008 Feb;9(2):102-14
pubmed: 18197166
Acc Chem Res. 2021 Jan 19;54(2):291-301
pubmed: 33180454
Nat Cell Biol. 2019 Dec;21(12):1578-1589
pubmed: 31792379
Nat Commun. 2020 Oct 7;11(1):5053
pubmed: 33028821
Nature. 2004 Mar 25;428(6981):371
pubmed: 15042068
Nature. 2019 Sep;573(7772):69-74
pubmed: 31435009
Nat Commun. 2017 Jul 24;8:16013
pubmed: 28737169
Nat Phys. 2017 Aug;13(8):771-775
pubmed: 28781604
Annu Rev Biomed Eng. 2009;11:259-88
pubmed: 19400709
Cell. 2014 Aug 14;158(4):822-832
pubmed: 25126787
Nat Cell Biol. 2013 Jul;15(7):751-62
pubmed: 23792690
Front Cell Neurosci. 2017 Apr 20;11:93
pubmed: 28473753
Nat Cell Biol. 1999 May;1(1):E13-5
pubmed: 10559875
Biol Reprod. 1996 Jan;54(1):100-10
pubmed: 8838006
Annu Rev Cell Dev Biol. 2016 Oct 6;32:527-554
pubmed: 27298087
EMBO J. 2000 Feb 15;19(4):513-20
pubmed: 10675320
Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):E1523-9
pubmed: 22615348
Nat Mater. 2017 Mar;16(3):379-389
pubmed: 27798620
Nat Cell Biol. 2020 Apr;22(4):453-464
pubmed: 32203417
Curr Opin Cell Biol. 2017 Jun;46:119-127
pubmed: 28641092
Soft Matter. 2019 Jan 2;15(2):190-199
pubmed: 30488938
Nat Rev Genet. 2013 Oct;14(10):733-44
pubmed: 24045690
Sci Immunol. 2019 Mar 22;4(33):
pubmed: 30902904
Nature. 2006 Mar 2;440(7080):32-4
pubmed: 16511477
J Cell Sci. 2016 Sep 15;129(18):3375-83
pubmed: 27550520
Science. 2016 May 6;352(6286):aad6933
pubmed: 27151873
Nat Cell Biol. 2018 Apr;20(4):373-381
pubmed: 29467443
Bioessays. 2017 Jan;39(1):1-12
pubmed: 27930828
Cell. 2016 Mar 24;165(1):100-110
pubmed: 26924577
Mol Immunol. 2018 Sep;101:319-328
pubmed: 30036798
Mol Cell. 2020 Sep 17;79(6):978-990.e5
pubmed: 32857953
J Cell Biochem. 2010 Feb 15;109(3):460-7
pubmed: 20024954
Proc Natl Acad Sci U S A. 2016 May 10;113(19):5293-8
pubmed: 27114541
Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):128-134
pubmed: 31843897
Nat Mater. 2016 Dec;15(12):1287-1296
pubmed: 27548707
Cell. 2003 Feb 21;112(4):467-80
pubmed: 12600311
Sci Adv. 2020 Mar 04;6(10):eaax1909
pubmed: 32181337
Glia. 2007 Oct;55(13):1334-47
pubmed: 17647290
Intensive Care Med Exp. 2015 Dec;3(1):39
pubmed: 26215806
Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13872-7
pubmed: 20643929
Ultramicroscopy. 2010 Nov;110(12):1435-42
pubmed: 20728993
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4872-7
pubmed: 20194780
Nat Phys. 2019 Sep;15(9):973-981
pubmed: 37484710
FASEB J. 2012 Oct;26(10):4045-56
pubmed: 22707566
Nat Mater. 2017 Dec;16(12):1243-1251
pubmed: 28967913
ACS Nano. 2014 Mar 25;8(3):2033-47
pubmed: 24483337
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4075-4080
pubmed: 29618614
Cell Rep. 2019 Jan 2;26(1):94-107.e7
pubmed: 30605689
Nat Mater. 2018 Dec;17(12):1134-1144
pubmed: 30349032
Science. 2005 May 27;308(5726):1314-8
pubmed: 15831717
Annu Rev Biophys. 2008;37:375-97
pubmed: 18573087
Nature. 2002 Mar 28;416(6879):413-6
pubmed: 11919627
Langmuir. 2019 Jun 11;35(23):7571-7577
pubmed: 30281318
Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17175-17180
pubmed: 31409716
Nat Phys. 2018 Jun;14:613-620
pubmed: 30151030
Nature. 2016 Nov 24;539(7630):560-564
pubmed: 27851739
Cell. 2013 Mar 14;152(6):1376-89
pubmed: 23498944
Biophys J. 2012 Feb 8;102(3):434-42
pubmed: 22325265