Role of vitamin C in preventing of COVID-19 infection, progression and severity.
COVID-19
SARS-CoV-2
anti-oxidant
antiviral
sepsis
vitamin C
Journal
AIMS microbiology
ISSN: 2471-1888
Titre abrégé: AIMS Microbiol
Pays: United States
ID NLM: 101697141
Informations de publication
Date de publication:
2022
2022
Historique:
received:
04
12
2021
revised:
21
02
2022
accepted:
21
03
2022
entrez:
2
5
2022
pubmed:
3
5
2022
medline:
3
5
2022
Statut:
epublish
Résumé
Vitamin C stands as an essential water-soluble vitamin, antioxidant and has been shown to enhance immunity. SARS-CoV-2 has been spreading rapidly across the worldwide, several cellular processes of innate and adaptive immunity are aided by vitamin C, which strengthens the immune system overall. Multiple lines of evidence in the literature associate vitamin C with antioxidant, anti-inflammatory, anticoagulant and immunomodulatory actions. Pneumonia and sepsis patients had poor ascorbic acid status and high oxidative stress, according to many studies. Pneumonia patients who get vitamin C may have less severe symptoms and a longer course of the illness if they do. To standardize plasma levels in sepsis patients, gram measurements of the vitamin must be administered intravenously (IV). This intervention has been shown in a few trials to reduce mortality. COVID-19 management in China and the United States has exhibited remarkable results when using a high percentage of intravenous vitamins C. It's acceptable to include vitamin C in the COVID-19 treatment protocol as a secondary measure based on the current active clinical studies looking at the impact of vitamin C on the management of COVID-19. Patients with hypovitaminosis C or severe respiratory illnesses, such as COVID-19, may benefit from taking vitamin C, due to its good safety profile, simplicity of use, and potential for rapid production scaling. The study's goal was to see whether high dosage intravenous vitamin C had any impact on individuals with severe COVID-19 (HDIVC). Finally we discuss recent research that has been published on the efficacy of vitamin C administration in the treatment of viral infection and life-threatening conditions. The purpose of this manuscript is to summarise existing research on the efficacy of vitamin C as a treatment for COVID-19 and to discuss possible explanations for why it may work in some individuals but not in others.
Identifiants
pubmed: 35496992
doi: 10.3934/microbiol.2022010
pii: microbiol-08-01-010
pmc: PMC8995185
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
108-124Informations de copyright
© 2022 the Author(s), licensee AIMS Press.
Déclaration de conflit d'intérêts
Conflict of interest: The authors declare no conflict of interest.
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