Non-cytotoxic, temperature-responsive and antibacterial POEGMA based nanocomposite coatings with silver nanoparticles.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
06 Mar 2020
06 Mar 2020
Historique:
received:
24
12
2019
accepted:
28
02
2020
entrez:
2
5
2022
pubmed:
10
3
2020
medline:
10
3
2020
Statut:
epublish
Résumé
Non-cytotoxic, temperature-responsive and antibacterial poly(di(ethylene glycol)methyl ether methacrylate) - POEGMA188 based nanocomposite coatings attached to a glass surface were successfully prepared using ATRP polymerization. The thickness, morphology and wettability of the resulting coatings were analyzed using ellipsometry, AFM and contact angle measurements, respectively. The strong impact of the thicknesses of the POEGMA188 grafted brush coatings and content of AgNPs on the morphology and temperature-induced wettability changes of the nanocomposite was demonstrated. In addition to the strong temperature-dependent antibacterial activity, the proposed nanocomposite coatings have no significant cytotoxic effect towards normal cells. Moreover, the slight anti-cancer effect of AgNPs may be suggested.
Identifiants
pubmed: 35498562
doi: 10.1039/c9ra10874b
pii: c9ra10874b
pmc: PMC9050227
doi:
Types de publication
Journal Article
Langues
eng
Pagination
10155-10166Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
All authors have no conflict of interest.
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