Resolving dyskinesias at sustained anti-OCD efficacy by steering of DBS away from the anteromedial STN to the mesencephalic ventral tegmentum - case report.
Anteromedial STN
Case report
DBS
Directional
Focal
Mesencephalic ventral tegmentum
Obsessive–compulsive disorder
slMFB
Journal
Acta neurochirurgica
ISSN: 0942-0940
Titre abrégé: Acta Neurochir (Wien)
Pays: Austria
ID NLM: 0151000
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
24
02
2022
accepted:
03
04
2022
pubmed:
3
5
2022
medline:
3
9
2022
entrez:
2
5
2022
Statut:
ppublish
Résumé
Here we describe therapeutic results in a female patient who underwent bilateral slMFB DBS for OCD. During a 35-month long course of stimulation, she suffered from stimulation-induced dyskinesia of her right leg which we interpreted as co-stimulation of the adjacent anteromedial subthalamic nucleus (amSTN). After reprogramming to steer the stimulation away from the amSTN medial into the direction of the mesencephalic ventral tegmentum (MVT which contains the ventral tegmental area, VTA), the dyskinesias disappeared. Remarkably, anti-OCD efficacy in the presented patient was preserved and achieved with a bilateral stimulation which by our imaging study fully avoided the amSTN.
Identifiants
pubmed: 35499574
doi: 10.1007/s00701-022-05206-w
pii: 10.1007/s00701-022-05206-w
pmc: PMC9427876
doi:
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2303-2307Informations de copyright
© 2022. The Author(s).
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