Incidence and prognostic impact of the calcified nodule in coronary artery disease patients with end-stage renal disease on dialysis.
Calcified nodule
Coronary artery disease
Dialysis
Optical coherence tomography
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
07
11
2021
accepted:
08
04
2022
pubmed:
3
5
2022
medline:
26
8
2022
entrez:
2
5
2022
Statut:
ppublish
Résumé
Coronary artery calcification is frequently observed in coronary artery disease (CAD) patients with end-stage renal disease (ESRD). Calcified nodule (CN) is recognized as one of the vulnerable plaque characteristics responsible for acute coronary syndrome (ACS). Although CN is a cause of ACS in only 10%, its prevalence may be higher in elderly patients and/or ESRD. The aim of this study is to investigate incidence, clinical characteristics, and prognostic impact of CN in CAD patients with ESRD on dialysis. A total of 51 vessels from 49 CAD patients with ESRD on dialysis were enrolled in this study. CN was defined as a high-backscattering mass protruding into the lumen with a strong signal attenuation and an irregular surface by optical coherence tomography. Incidence, clinical characteristics and prognosis of patients with CN were studied. Major adverse cardiac events (MACE) were defined as a composite of all-cause death, non-fatal myocardial infarction, target vessel revascularization (TVR) and stroke. CNs were observed in 30 vessels from 29 patients (59.2%). Duration of dialysis was significantly longer in CN group than in non-CN group (P = 0.03). Overall, all-cause death, cardiac death, TVR and MACE occurred in 7 (14.3%), 3 (6.1%), 11 (22.4%) and 16 (32.7%) patients during follow-up (median 826 days), respectively. Kaplan-Meier survival analysis revealed that MACE-free survival was significantly lower in patients with CN compared with those without CN (Log-rank, P = 0.036).In conclusion, CN was observed in about 60% of the CAD patients with ESRD and was associated with duration of dialysis and worse prognosis.
Identifiants
pubmed: 35499643
doi: 10.1007/s00380-022-02076-1
pii: 10.1007/s00380-022-02076-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1662-1668Informations de copyright
© 2022. Springer Japan KK, part of Springer Nature.
Références
Genereux P, Redfors B, Witzenbichler B, Arsenault MP, Weisz G, Stuckey TD, Rinaldi MJ, Neumann FJ, Christopher Metzger D, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Francese DP, Marquis-Gravel G, Mintz GS, Kirtane AJ, Maehara A, Mehran R, Stone GW (2017) Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents. Int J Cardiol 231:61–67
pubmed: 28040289
doi: 10.1016/j.ijcard.2016.12.150
Goodman WG, Goldin J, Kuizon BD, Yoon C, Gales B, Sider D, Wang Y, Chung J, Emerick A, Greaser L, Elashoff RM, Salusky IB (2000) Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 342(20):1478–1483
pubmed: 10816185
doi: 10.1056/NEJM200005183422003
Sugiura J, Watanabe M, Toyokawa N, Kamon D, Isojima T, Ueda T, Soeda T, Okura H, Saito Y (2019) Progression of a calcified nodule causing acute myocardial infarction in a patient on hemodialysis—serial optical coherence tomography. Circ J 83(2):490
pubmed: 30146552
doi: 10.1253/circj.CJ-18-0515
Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20(5):1262–1275
pubmed: 10807742
doi: 10.1161/01.ATV.20.5.1262
Kobayashi Y, Okura H, Kume T, Yamada R, Kobayashi Y, Fukuhara K, Koyama T, Nezuo S, Neishi Y, Hayashida A, Kawamoto T, Yoshida K (2014) Impact of target lesion coronary calcification on stent expansion. Circ J 78(9):2209–2214
pubmed: 25017740
doi: 10.1253/circj.CJ-14-0108
Kume T, Okura H, Kawamoto T, Yamada R, Miyamoto Y, Hayashida A, Watanabe N, Neishi Y, Sadahira Y, Akasaka T, Yoshida K (2011) Assessment of the coronary calcification by optical coherence tomography. EuroIntervention 6(6):768–772
pubmed: 21205603
doi: 10.4244/EIJV6I6A130
Sugawara Y, Ueda T, Soeda T, Watanabe M, Okura H, Saito Y (2019) Plaque modification of severely calcified coronary lesions by scoring balloon angioplasty using Lacrosse non-slip element: insights from an optical coherence tomography evaluation. Cardiovasc Interv Ther 34(3):242–248
pubmed: 30341585
doi: 10.1007/s12928-018-0553-6
Ueda T, Uemura S, Watanabe M, Dote Y, Goryo Y, Sugawara Y, Soeda T, Okayama S, Kawata H, Kawakami R, Okura H, Saito Y (2016) Thin-cap fibroatheroma and large calcification at the proximal stent edge correlate with a high proportion of uncovered stent struts in the chronic phase. Coron Artery Dis 27(5):376–384
pubmed: 27164267
doi: 10.1097/MCA.0000000000000380
Ali ZA, Maehara A, Genereux P, Shlofmitz RA, Fabbiocchi F, Nazif TM, Guagliumi G, Meraj PM, Alfonso F, Samady H, Akasaka T, Carlson EB, Leesar MA, Matsumura M, Ozan MO, Mintz GS, Ben-Yehuda O, Stone GW, Investigators IIOP (2016) Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial. Lancet 388(10060):2618–2628
pubmed: 27806900
doi: 10.1016/S0140-6736(16)31922-5
Fujii K, Kubo T, Otake H, Nakazawa G, Sonoda S, Hibi K, Shinke T, Kobayashi Y, Ikari Y, Akasaka T (2020) Expert consensus statement for quantitative measurement and morphological assessment of optical coherence tomography. Cardiovasc Interv Ther 35(1):13–18
pubmed: 31602597
doi: 10.1007/s12928-019-00626-5
Kubo T, Shinke T, Okamura T, Hibi K, Nakazawa G, Morino Y, Shite J, Fusazaki T, Otake H, Kozuma K, Ioji T, Kaneda H, Serikawa T, Kataoka T, Okada H, Akasaka T, OPINION Investigators (2017) Optical frequency domain imaging vs intravascular ultrasound in percutaneous coronary intervention (OPINION trial): one-year angiographic and clinical results. Eur Heart J 38(42):3139–3147
pubmed: 29121226
pmcid: 5837511
doi: 10.1093/eurheartj/ehx351
Okura H, Saito Y, Soeda T, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Nishimura K, Miyamoto Y, Ishihara M, J-MINUET Investigators (2019) Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET. Heart Vessels 34(4):564–571
pubmed: 30390126
doi: 10.1007/s00380-018-1285-3
Sonoda S, Hibi K, Okura H, Fujii K, Honda Y, Kobayashi Y (2020) Current clinical use of intravascular ultrasound imaging to guide percutaneous coronary interventions. Cardiovasc Interv Ther 35(1):30–36
pubmed: 31281937
doi: 10.1007/s12928-019-00603-y
Tearney GJ, Regar E, Akasaka T, Adriaenssens T, Barlis P, Bezerra HG, Bouma B, Bruining N, Cho JM, Chowdhary S, Costa MA, de Silva R, Dijkstra J, Di Mario C, Dudek D, Falk E, Feldman MD, Fitzgerald P, Garcia-Garcia HM, Gonzalo N, Granada JF, Guagliumi G, Holm NR, Honda Y, Ikeno F, Kawasaki M, Kochman J, Koltowski L, Kubo T, Kume T, Kyono H, Lam CC, Lamouche G, Lee DP, Leon MB, Maehara A, Manfrini O, Mintz GS, Mizuno K, Morel MA, Nadkarni S, Okura H, Otake H, Pietrasik A, Prati F, Raber L, Radu MD, Rieber J, Riga M, Rollins A, Rosenberg M, Sirbu V, Serruys PW, Shimada K, Shinke T, Shite J, Siegel E, Sonoda S, Suter M, Takarada S, Tanaka A, Terashima M, Thim T, Uemura S, Ughi GJ, van Beusekom HM, van der Steen AF, van Es GA, van Soest G, Virmani R, Waxman S, Weissman NJ, Weisz G, International Working Group for Intravascular Optical Coherence Tomography (2012) Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol 59(12):1058–1072
pubmed: 22421299
doi: 10.1016/j.jacc.2011.09.079
Terashima M, Kaneda H, Honda Y, Shimura T, Kodama A, Habara M, Suzuki T (2021) Current status of hybrid intravascular ultrasound and optical coherence tomography catheter for coronary imaging and percutaneous coronary intervention. J Cardiol 77(5):435–443
pubmed: 33158714
doi: 10.1016/j.jjcc.2020.08.012
Watanabe M, Okura H, Okamura A, Iwai S, Keshi A, Kamon D, Isojima T, Ueda T, Soeda T, Saito Y (2019) Usefulness of longitudinal reconstructed optical coherence tomography images for predicting the need for the reverse wire technique during coronary bifurcation interventions. Catheter Cardiovasc Interv 94(2):E54–E60
pubmed: 30474184
doi: 10.1002/ccd.27981
Yamashita T, Sakamoto K, Tabata N, Ishii M, Sato R, Nagamatsu S, Motozato K, Yamanaga K, Sueta D, Araki S, Arima Y, Yamamoto E, Takashio S, Fujisue K, Fujimoto K, Shimomura H, Tsunoda R, Maruyama H, Nakamura N, Sakaino N, Nakamura S, Yamamoto N, Matsumura T, Kajiwara I, Tayama S, Sakamoto T, Nakao K, Oshima S, Kaikita K, Hokimoto S, Tsujita K, Kumamoto Intervention Conference Study Investigators (2021) Imaging-guided PCI for event suppression in Japanese acute coronary syndrome patients: community-based observational cohort registry. Cardiovasc Interv Ther 36(1):81–90
pubmed: 32052349
doi: 10.1007/s12928-020-00649-3
Iwai S, Watanabe M, Okamura A, Kyodo A, Nogi K, Kamon D, Hashimoto Y, Ueda T, Soeda T, Okura H, Saito Y (2021) Prognostic impact of calcified plaque morphology after newer generation drug eluting stent implantation: an optical coherence tomography study. Circ J 85(11):2019–2028
pubmed: 34039823
doi: 10.1253/circj.CJ-20-1233
Iseki K, Fukiyama K (2000) Long-term prognosis and incidence of acute myocardial infarction in patients on chronic hemodialysis. The Okinawa Dialysis Study Group. Am J Kidney Dis 36(4):820–825
pubmed: 11007686
doi: 10.1053/ajkd.2000.17676
Herzog CA, Ma JZ, Collins AJ (1998) Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. N Engl J Med 339(12):799–805
pubmed: 9738087
doi: 10.1056/NEJM199809173391203
Jia H, Abtahian F, Aguirre AD, Lee S, Chia S, Lowe H, Kato K, Yonetsu T, Vergallo R, Hu S, Tian J, Lee H, Park SJ, Jang YS, Raffel OC, Mizuno K, Uemura S, Itoh T, Kakuta T, Choi SY, Dauerman HL, Prasad A, Toma C, McNulty I, Zhang S, Yu B, Fuster V, Narula J, Virmani R, Jang IK (2013) In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography. J Am Coll Cardiol 62(19):1748–1758
pubmed: 23810884
doi: 10.1016/j.jacc.2013.05.071
Xu Y, Mintz GS, Tam A, McPherson JA, Iniguez A, Fajadet J, Fahy M, Weisz G, De Bruyne B, Serruys PW, Stone GW, Maehara A (2012) Prevalence, distribution, predictors, and outcomes of patients with calcified nodules in native coronary arteries: a 3-vessel intravascular ultrasound analysis from Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT). Circulation 126(5):537–545
pubmed: 22744975
doi: 10.1161/CIRCULATIONAHA.111.055004
Lee T, Mintz GS, Matsumura M, Zhang W, Cao Y, Usui E, Kanaji Y, Murai T, Yonetsu T, Kakuta T, Maehara A (2017) Prevalence, predictors, and clinical presentation of a calcified nodule as assessed by optical coherence tomography. JACC Cardiovasc Imaging 10(8):883–891
pubmed: 28797410
doi: 10.1016/j.jcmg.2017.05.013
Aoki J, Nakazawa G, Ando K, Nakamura S, Tobaru T, Sakurada M, Okada H, Hibi K, Zen K, Ikuta A, Fujii K, Habara M, Ako J, Asano T, Ozaki S, Fusazaki T, Kozuma K, ELEGANT Investigators (2020) Impact of hemodialysis on clinical and angiographic outcomes in in-stent restenotic lesions following optical coherence tomography-guided drug-coated balloon treatment. Cardiovasc Interv Ther 36(4):429–435
pubmed: 33048289
doi: 10.1007/s12928-020-00718-7
Kimura T, Morimoto T, Nakagawa Y, Kawai K, Miyazaki S, Muramatsu T, Shiode N, Namura M, Sone T, Oshima S, Nishikawa H, Hiasa Y, Hayashi Y, Nobuyoshi M, Mitudo K, j-Cypher Registry Investigators (2012) Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry. Circulation 125(4):584–591
pubmed: 22203694
doi: 10.1161/CIRCULATIONAHA.111.046599
Numasawa Y, Inohara T, Ishii H, Yamaji K, Hirano K, Kohsaka S, Sawano M, Kuno T, Kodaira M, Uemura S, Kadota K, Amano T, Nakamura M, Investigators JPR (2019) An overview of percutaneous coronary intervention in dialysis patients: insights from a Japanese nationwide registry. Catheter Cardiovasc Interv 94(1):E1–E8
pubmed: 30467967
doi: 10.1002/ccd.27986
Higuma T, Soeda T, Abe N, Yamada M, Yokoyama H, Shibutani S, Vergallo R, Minami Y, Ong DS, Lee H, Okumura K, Jang IK (2015) A combined optical coherence tomography and intravascular ultrasound study on plaque rupture, plaque erosion, and calcified nodule in patients with ST-segment elevation myocardial infarction: incidence, morphologic characteristics, and outcomes after percutaneous coronary intervention. JACC Cardiovasc Interv 8(9):1166–1176
pubmed: 26117464
doi: 10.1016/j.jcin.2015.02.026
Kajander OA, Pinilla-Echeverri N, Jolly SS, Bhindi R, Huhtala H, Niemela K, Fung A, Vijayaraghavan R, Alexopoulos D, Sheth T (2016) Culprit plaque morphology in STEMI—an optical coherence tomography study: insights from the TOTAL-OCT substudy. EuroIntervention 12(6):716–723
pubmed: 27542783
doi: 10.4244/EIJV12I6A116
Khalifa AKM, Kubo T, Ino Y, Terada K, Emori H, Higashioka D, Katayama Y, Takahata M, Shimamura K, Shiono Y, Matsuo Y, Tanaka A, Hozumi T, Akasaka T (2020) Optical coherence tomography comparison of percutaneous coronary intervention among plaque rupture, erosion, and calcified nodule in acute myocardial infarction. Circ J 84(6):911–916
pubmed: 32307358
doi: 10.1253/circj.CJ-20-0014
Sato Y, Finn AV, Virmani R (2021) Calcified nodule: a rare but important cause of acute coronary syndrome with worse clinical outcomes. Atherosclerosis 318:40–42
pubmed: 33353729
doi: 10.1016/j.atherosclerosis.2020.12.009
Wang L, Parodi G, Maehara A, Valenti R, Migliorini A, Vergara R, Carrabba N, Mintz GS, Antoniucci D (2015) Variable underlying morphology of culprit plaques associated with ST-elevation myocardial infarction: an optical coherence tomography analysis from the SMART trial. Eur Heart J Cardiovasc Imaging 16(12):1381–1389
pubmed: 25911115
doi: 10.1093/ehjci/jev105
Morofuji T, Kuramitsu S, Shinozaki T, Jinnouchi H, Sonoda S, Domei T, Hyodo M, Shirai S, Ando K (2021) Clinical impact of calcified nodule in patients with heavily calcified lesions requiring rotational atherectomy. Catheter Cardiovasc Interv 97(1):10–19
pubmed: 32259392
doi: 10.1002/ccd.28896
Nakamura N, Torii S, Tsuchiya H, Nakano A, Oikawa Y, Yajima J, Nakamura S, Nakano M, Masuda N, Ohta H, Yumoto K, Natsumeda M, Ijichi T, Ikari Y, Nakazawa G (2020) Formation of calcified nodule as a cause of early in-stent restenosis in patients undergoing dialysis. J Am Heart Assoc 9(19):e016595
pubmed: 32964759
pmcid: 7792410
doi: 10.1161/JAHA.120.016595
Isodono K, Fujii K, Fujimoto T, Kasahara T, Ariyoshi M, Irie D, Tsubakimoto Y, Sakatani T, Matsuo A, Inoue K, Fujita H (2021) The frequency and clinical characteristics of in-stent restenosis due to calcified nodule development after coronary stent implantation. Int J Cardiovasc Imaging 37(1):15–23
pubmed: 32734495
doi: 10.1007/s10554-020-01952-z
Kyodo A, Watanabe M, Okamura A, Iwai S, Sakagami A, Nogi K, Kamon D, Hashimoto Y, Ueda T, Soeda T, Okura H, Saito Y (2021) Post-stent optical coherence tomography findings at index percutaneous coronary intervention—characteristics related to subsequent stent thrombosis. Circ J 85(6):857–866
pubmed: 33504743
doi: 10.1253/circj.CJ-20-0759
Ishida M, Ishisone T, Kimura T, Morino Y (2022) Stent-less percutaneous coronary intervention of calcified nodule causing non-ST-elevation myocardial infarction—serial optical coherence tomography follow-up after rotational atherectomy followed by drug-coated balloon angioplasty. Circ J 86(2):336
pubmed: 34602583
doi: 10.1253/circj.CJ-21-0628
Ito R, Ishii H, Oshima S, Nakayama T, Sakakibara T, Kakuno M, Murohara T (2021) Outcomes after drug-coated balloon interventions for de novo coronary lesions in the patients on chronic hemodialysis. Heart Vessels 36(11):1646–1652
pubmed: 33895872
doi: 10.1007/s00380-021-01858-3
Okutsu M, Mitomo S, Ouchi T, Yuki H, Ueno T, Onish H, Yabushita H, Matsuoka S, Kawamoto H, Watanabe Y, Tanaka K, Naganuma T, Sato T, Tahara S, Kurita N, Nakamura S, Nakamura S (2022) Impact of directional coronary atherectomy followed by drug-coated balloon strategy to avoid the complex stenting for bifurcation lesions. Heart Vessels. https://doi.org/10.1007/s00380-021-02000-z
doi: 10.1007/s00380-021-02000-z
pubmed: 34981167
Ueno K, Morita N, Kojima Y, Takahashi H, Kawasaki M, Ito R, Kondo H, Minatoguchi S, Yoshida T, Hashimoto Y, Tatsumi T, Kitamura T (2019) Safety and long-term efficacy of drug-coated balloon angioplasty following rotational atherectomy for severely calcified coronary lesions compared with new generation drug-eluting stents. J Interv Cardiol 2019:9094178
pubmed: 31772551
pmcid: 6739772
doi: 10.1155/2019/9094178
Fellstrom BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Gronhagen-Riska C, De Lima JJ, Lins R, Mayer G, McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Suleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wuthrich RP, Gottlow M, Johnsson E, Zannad F, AS Group (2009) Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 360(14):1395–1407
pubmed: 19332456
doi: 10.1056/NEJMoa0810177
Wanner C, Krane V, Marz W, Olschewski M, Mann JF, Ruf G, Ritz E, German D, German Diabetes and Dialysis Study Investigators (2005) Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 353(3):238–248
pubmed: 16034009
doi: 10.1056/NEJMoa043545
Marui A, Kimura T, Nishiwaki N, Mitsudo K, Komiya T, Hanyu M, Shiomi H, Tanaka S, Sakata R, CR-KPCRC Investigators (2014) Comparison of five-year outcomes of coronary artery bypass grafting versus percutaneous coronary intervention in patients with left ventricular ejection fractions</=50% versus >50% (from the CREDO-Kyoto PCI/CABG Registry Cohort-2). Am J Cardiol 114(7):988–996
pubmed: 25124184
doi: 10.1016/j.amjcard.2014.07.007
Watanabe Y, Sakakura K, Taniguchi Y, Yamamoto K, Seguchi M, Tsukui T, Jinnouchi H, Wada H, Momomura SI, Fujita H (2020) Comparison of clinical outcomes of intravascular ultrasound-calcified nodule between percutaneous coronary intervention with versus without rotational atherectomy in a propensity-score matched analysis. PLoS One 15(11):e0241836
pubmed: 33152027
pmcid: 7643997
doi: 10.1371/journal.pone.0241836
Sakakura K (2021) Lesion preparation for severely calcified coronary artery disease—intravascular lithotripsy as a new option. Circ J 85(6):834–836
pubmed: 33583927
doi: 10.1253/circj.CJ-20-1272
Sakakura K, Ito Y, Shibata Y, Okamura A, Kashima Y, Nakamura S, Hamazaki Y, Ako J, Yokoi H, Kobayashi Y, Ikari Y (2021) Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics. Cardiovasc Interv Ther 36(1):1–18
pubmed: 33079355
doi: 10.1007/s12928-020-00715-w