Differential hydrogen sulfide production by a human cohort in response to animal- and plant-based diet interventions.

16S rRNA gene Dietary sulfur Hydrogen sulfide Microfluidic qPCR Sulfate-reducing bacteria

Journal

Clinical nutrition (Edinburgh, Scotland)
ISSN: 1532-1983
Titre abrégé: Clin Nutr
Pays: England
ID NLM: 8309603

Informations de publication

Date de publication:
06 2022
Historique:
received: 13 02 2022
revised: 24 03 2022
accepted: 30 03 2022
pubmed: 3 5 2022
medline: 7 6 2022
entrez: 2 5 2022
Statut: ppublish

Résumé

Hydrogen sulfide (H Determine the effect of short-term (1-week) plant- and animal-based eating patterns on ex vivo fecal H The study design was an open-label, cross-over diet study and diets were self-administered. Each participant consumed two interventional diets: 1) an animal-based, low fiber (i.e. western) diet and 2) a plant-based, high fiber diet, separated by a two-week washout period. Participants collected full stool samples at the end of each week, which were processed within 2 h of collection to capture H Median H Here we report that substrate changes associated with a 1-week plant-based diet intervention resulted in lower ex vivo H

Sections du résumé

BACKGROUND
Hydrogen sulfide (H
OBJECTIVE
Determine the effect of short-term (1-week) plant- and animal-based eating patterns on ex vivo fecal H
METHODS
The study design was an open-label, cross-over diet study and diets were self-administered. Each participant consumed two interventional diets: 1) an animal-based, low fiber (i.e. western) diet and 2) a plant-based, high fiber diet, separated by a two-week washout period. Participants collected full stool samples at the end of each week, which were processed within 2 h of collection to capture H
RESULTS
Median H
CONCLUSIONS
Here we report that substrate changes associated with a 1-week plant-based diet intervention resulted in lower ex vivo H

Identifiants

pubmed: 35500315
pii: S0261-5614(22)00111-X
doi: 10.1016/j.clnu.2022.03.028
pii:
doi:

Substances chimiques

Dietary Fiber 0
Hydrogen 7YNJ3PO35Z
Hydrogen Sulfide YY9FVM7NSN

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1153-1162

Informations de copyright

Copyright © 2022 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no conflicts of interest.

Auteurs

Levi Teigen (L)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Prince P Mathai (PP)

BioTechnology Institute, University of Minnesota, St. Paul, MN, USA.

Sharon Lopez (S)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Michael Matson (M)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Baila Elkin (B)

Medical School, University of Minnesota, Minneapolis, MN, USA.

Daria Kozysa (D)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Amanda J Kabage (AJ)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Matthew Hamilton (M)

BioTechnology Institute, University of Minnesota, St. Paul, MN, USA.

Byron P Vaughn (BP)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Michael J Sadowsky (MJ)

BioTechnology Institute, University of Minnesota, St. Paul, MN, USA; Department of Soil, Water, and Climate, USA; Department of Plant and Microbial Biology, USA.

Alexander Khoruts (A)

Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA; BioTechnology Institute, University of Minnesota, St. Paul, MN, USA; Center for Immunology, University of Minnesota, Minneapolis, MN, USA. Electronic address: khoru001@umn.edu.

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Classifications MeSH