Lessons Learned from the Impact of COVID-19 on NCI-sponsored Cancer Prevention Clinical Trials: Moving Toward Participant-centric Study Designs.


Journal

Cancer prevention research (Philadelphia, Pa.)
ISSN: 1940-6215
Titre abrégé: Cancer Prev Res (Phila)
Pays: United States
ID NLM: 101479409

Informations de publication

Date de publication:
03 05 2022
Historique:
received: 19 11 2021
revised: 19 01 2022
accepted: 27 01 2022
entrez: 3 5 2022
pubmed: 4 5 2022
medline: 6 5 2022
Statut: ppublish

Résumé

The COVID-19 pandemic overloaded health care systems around the globe and brought travel restrictions and other mandates. These effects critically impacted cancer care and conduct of clinical trials, and required medical and research communities to incorporate changes and novel flexible workflows within clinical trials and regulations to improve efficiency. We report the impact of the pandemic on cancer prevention clinical trials managed by the Division of Cancer Prevention within the NCI, focusing on participant-centric, study staff-centric and regulatory elements. Learning lessons from this challenging period, the cancer prevention community has the opportunity to incorporate many of these necessitated novel approaches to future design of clinical trials, to streamline and improve clinical trial efficiency and impact.

Identifiants

pubmed: 35502553
pii: 694469
doi: 10.1158/1940-6207.CAPR-21-0578
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

279-284

Subventions

Organisme : NCI NIH HHS
ID : UG1 CA242596
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA242635
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA242643
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States

Informations de copyright

©2022 American Association for Cancer Research.

Auteurs

Goli Samimi (G)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Margaret House (M)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Kelly Benante (K)

Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois.

Lisa Bengtson (L)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Troy Budd (T)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Bridget Dermody (B)

University of Wisconsin-Madison, Madison, Wisconsin.

Katina DeShong (K)

University of Wisconsin-Madison, Madison, Wisconsin.

Valerie Dyer (V)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Bruce F Kimler (BF)

University of Kansas Medical Center, Kansas City, Kansas.

Vikrant V Sahasrabuddhe (VV)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Suzanne Siminski (S)

Frontier Science Foundation, Amherst, New York.

Leslie G Ford (LG)

Division of Cancer Prevention, NCI, Rockville, Maryland.

Eduardo Vilar (E)

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Eva Szabo (E)

Division of Cancer Prevention, NCI, Rockville, Maryland.

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