Sphingomyelin Synthase Family and Phospholipase Cs.
Metabolic diseases
Phospholipase C
Sphingomyelin synthase
Journal
Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
3
5
2022
pubmed:
4
5
2022
medline:
6
5
2022
Statut:
ppublish
Résumé
The sphingomyelin synthase (SMS) gene family has three members: SMS1 and SMS2 have SM synthase activity, while SMS-related protein (SMSr) has no SM synthase activity but has ceramide phosphorylethanolamine (CPE) synthase activity in vitro. Recently, we found that SMS family members are a group of phospholipase Cs (PLC). SMS1 and SMS2 are two phosphatidylcholine (PC)-PLCs and SMSr is a phosphatidylethanolamine (PE)-PLC. SMS family members not only influence SM levels but also influence the levels of diacylglycerol (DAG), PC, PE, and glycosphingolipids, thus influencing cell functions. In this chapter, we will discuss the recent progress in the research field of SMS family and will focus on its impact on metabolic diseases.
Identifiants
pubmed: 35503176
doi: 10.1007/978-981-19-0394-6_7
pmc: PMC9251732
mid: NIHMS1818690
doi:
Substances chimiques
Phosphatidylcholines
0
Sphingomyelins
0
Transferases (Other Substituted Phosphate Groups)
EC 2.7.8.-
phosphatidylcholine-ceramide phosphocholine transferase
EC 2.7.8.-
Phospholipases
EC 3.1.-
Type C Phospholipases
EC 3.1.4.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
77-86Subventions
Organisme : BLRD VA
ID : I01 BX000900
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL139582
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL149730
Pays : United States
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd.
Références
Biochim Biophys Acta. 2008 Oct;1781(10):610-7
pubmed: 18694848
J Cell Biol. 2009 Jun 15;185(6):1013-27
pubmed: 19506037
Protein Sci. 1997 Aug;6(8):1764-7
pubmed: 9260289
Gene. 2011 Aug 1;481(2):65-75
pubmed: 21549185
Gut. 2021 Oct;70(10):1954-1964
pubmed: 33208407
Proc Natl Acad Sci U S A. 1996 May 14;93(10):4638-43
pubmed: 8643456
Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):850-6
pubmed: 19286635
J Cell Sci. 2014 Jan 15;127(Pt 2):445-54
pubmed: 24259670
Mol Biol Rep. 2013 Dec;40(12):6685-90
pubmed: 24062078
Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2114-20
pubmed: 20814016
Mol Microbiol. 2004 Aug;53(4):1089-98
pubmed: 15306013
Sci STKE. 2005 May 31;2005(286):re7
pubmed: 15928333
J Biol Chem. 2006 Oct 6;281(40):29421-5
pubmed: 16905542
Biochem J. 1991 Dec 1;280 ( Pt 2):295-302
pubmed: 1747103
J Lipid Res. 2015 Mar;56(3):537-545
pubmed: 25605874
J Biol Chem. 2011 Oct 14;286(41):36053-36062
pubmed: 21856749
J Biol Chem. 1998 Jun 5;273(23):14550-9
pubmed: 9603970
J Biol Chem. 2021 Jan-Jun;296:100454
pubmed: 33621517
Metabolism. 2000 Jan;49(1):22-31
pubmed: 10647060
J Biol Chem. 2018 Nov 23;293(47):18328-18336
pubmed: 30305392
J Biol Chem. 2004 Apr 30;279(18):18688-93
pubmed: 14976195
Front Oncol. 2016 Dec 27;6:266
pubmed: 28083512
Circ Res. 2009 Jul 31;105(3):295-303
pubmed: 19590047
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24
pubmed: 18216768
J Med Chem. 2018 Sep 27;61(18):8241-8254
pubmed: 30074791
J Lipid Res. 2009 Nov;50(11):2270-7
pubmed: 19454763
Cancers (Basel). 2019 Jan 14;11(1):
pubmed: 30646599
Trends Neurosci. 1989 Nov;12(11):425-32
pubmed: 2479143
Biochem Biophys Res Commun. 2020 Dec 17;533(4):1269-1275
pubmed: 33059919
Sci Signal. 2012 Nov 20;5(251):ra85
pubmed: 23169819
J Biol Chem. 2011 Aug 12;286(32):28544-55
pubmed: 21669879
PLoS One. 2013 Apr 12;8(4):e61380
pubmed: 23593476
Biochim Biophys Acta. 1994 Apr 14;1212(1):26-42
pubmed: 8155724
Biochim Biophys Acta. 1983 Dec 20;754(3):284-91
pubmed: 6652105
J Exp Med. 2005 Jul 18;202(2):249-59
pubmed: 16009715
EMBO J. 2004 Jan 14;23(1):33-44
pubmed: 14685263
J Biol Chem. 2012 Nov 23;287(48):40198-204
pubmed: 23066021
Biochim Biophys Acta Biomembr. 2019 Jul 1;1861(7):1284-1292
pubmed: 31067435
Mol Cell Biochem. 2015 Aug;406(1-2):91-9
pubmed: 25912551
Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May;1866(5):158898
pubmed: 33545384
J Biol Chem. 1997 Jul 11;272(28):17354-9
pubmed: 9211874
Mol Med. 2019 Dec 17;25(1):56
pubmed: 31847800
Annu Rev Physiol. 2013;75:127-54
pubmed: 23140367
Biochim Biophys Acta. 2016 Aug;1861(8 Pt A):688-702
pubmed: 27151272
iScience. 2018 Oct 26;8:250-266
pubmed: 30343189
Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Nov;1866(11):159017
pubmed: 34332077
PLoS One. 2016 Oct 27;11(10):e0164298
pubmed: 27788151
Biochim Biophys Acta. 2007 Sep;1771(9):1186-94
pubmed: 17616479
J Lipid Res. 2015 Apr;56(4):821-35
pubmed: 25667419
PLoS One. 2014 Jul 17;9(7):e102641
pubmed: 25032960
Biomed Res. 2019;40(5):189-196
pubmed: 31597904
J Am Heart Assoc. 2019 Nov 19;8(22):e012885
pubmed: 31718447
Biochim Biophys Acta Biomembr. 2017 Sep;1859(9 Pt B):1517-1525
pubmed: 28411172
Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84
pubmed: 22580896
Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19569-74
pubmed: 22106271
Sci Rep. 2017 Jan 25;7:41290
pubmed: 28120887
J Biol Chem. 2018 Nov 9;293(45):17505-17522
pubmed: 30242129
J Lipid Res. 2008 Feb;49(2):376-85
pubmed: 17982138
FEBS Lett. 2020 Nov;594(22):3751-3764
pubmed: 33037626
Am J Respir Cell Mol Biol. 2012 Jul;47(1):94-103
pubmed: 22362386
iScience. 2021 Nov 15;24(12):103449
pubmed: 34927020
Pharmazie. 2019 Sep 1;74(9):553-558
pubmed: 31484596
Infect Immun. 1992 Jan;60(1):219-30
pubmed: 1309513
Mol Cell Biol. 2011 Oct;31(20):4205-18
pubmed: 21844222
J Biol Chem. 2020 Mar 6;295(10):2932-2947
pubmed: 31980461
Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20
pubmed: 23640498
Neurochem Res. 2012 Apr;37(4):671-9
pubmed: 22101393
Biochem J. 2007 Jan 15;401(2):541-9
pubmed: 17049047
Sci Rep. 2016 Nov 28;6:37829
pubmed: 27892528
J Biol Chem. 2011 Feb 4;286(5):3992-4002
pubmed: 21115496
RNA Biol. 2015;12(9):1030-42
pubmed: 26274505
Drugs Exp Clin Res. 1996;22(6):287-94
pubmed: 9034754
Biochem Biophys Res Commun. 2017 Jan 8;482(2):202-207
pubmed: 27836537