Immunohistochemical loss of enhancer of Zeste Homolog 2 (EZH2) protein expression correlates with EZH2 alterations and portends a worse outcome in myelodysplastic syndromes.


Journal

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
ISSN: 1530-0285
Titre abrégé: Mod Pathol
Pays: United States
ID NLM: 8806605

Informations de publication

Date de publication:
09 2022
Historique:
received: 06 08 2021
accepted: 16 03 2022
revised: 15 03 2022
pubmed: 4 5 2022
medline: 1 9 2022
entrez: 3 5 2022
Statut: ppublish

Résumé

EZH2 coding mutation (EZH2

Identifiants

pubmed: 35504958
doi: 10.1038/s41379-022-01074-y
pii: S0893-3952(22)00276-9
doi:

Substances chimiques

Transcription Factors 0
EZH2 protein, human EC 2.1.1.43
Enhancer of Zeste Homolog 2 Protein EC 2.1.1.43

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1212-1219

Subventions

Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to United States & Canadian Academy of Pathology.

Références

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Auteurs

Ali Sakhdari (A)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Caleb Class (C)

Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Guillermo Montalban-Bravo (G)

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Koji Sasaki (K)

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Carlos E Bueso-Ramos (CE)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Keyur P Patel (KP)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Mark J Routbort (MJ)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Sanam Loghavi (S)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Chi Young Ok (CY)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Andres Quesada (A)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Joseph D Khoury (JD)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Sergej N Konoplev (SN)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Hagop P Kantarjian (HP)

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Guillermo Garcia-Manero (G)

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

L Jeffrey Medeiros (LJ)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Rashmi Kanagal-Shamanna (R)

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. RKanagal@mdanderson.org.

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