How the gut parasitome affects human health.

big-data omics human gut microbiome meiofauna prokaryota

Journal

Therapeutic advances in gastroenterology
ISSN: 1756-283X
Titre abrégé: Therap Adv Gastroenterol
Pays: England
ID NLM: 101478893

Informations de publication

Date de publication:
2022
Historique:
received: 16 09 2021
accepted: 23 02 2022
entrez: 5 5 2022
pubmed: 6 5 2022
medline: 6 5 2022
Statut: epublish

Résumé

The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.

Identifiants

pubmed: 35509426
doi: 10.1177/17562848221091524
pii: 10.1177_17562848221091524
pmc: PMC9058362
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

17562848221091524

Informations de copyright

© The Author(s), 2022.

Déclaration de conflit d'intérêts

Conflict of interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

Cell Res. 2020 Jun;30(6):492-506
pubmed: 32433595
Eur Arch Otorhinolaryngol. 2017 Feb;274(2):617-626
pubmed: 27115907
J Parasit Dis. 2016 Jun;40(2):217-26
pubmed: 27413282
Eur J Clin Microbiol Infect Dis. 2016 Sep;35(9):1427-31
pubmed: 27230509
Front Immunol. 2017 Apr 24;8:453
pubmed: 28484453
Pathogens. 2015 Nov 10;4(4):764-92
pubmed: 26569316
Infect Dis Poverty. 2019 Jun 15;8(1):49
pubmed: 31200765
Science. 2016 Apr 29;352(6285):608-12
pubmed: 27080105
Front Immunol. 2014 Oct 13;5:498
pubmed: 25352846
Front Med (Lausanne). 2018 Apr 16;5:90
pubmed: 29713629
Trends Parasitol. 2017 Dec;33(12):925-934
pubmed: 28870496
Trends Parasitol. 2021 Mar;37(3):251-262
pubmed: 33008723
Parasite Immunol. 2015 Jun;37(6):314-23
pubmed: 25869420
Clin Infect Dis. 2016 Sep 15;63(6):792-7
pubmed: 27313261
Nat Rev Gastroenterol Hepatol. 2020 Oct;17(10):635-648
pubmed: 32647386
Pharmacol Res. 2020 Sep;159:104962
pubmed: 32480001
PLoS Pathog. 2015 Aug 13;11(8):e1005039
pubmed: 26270819
ISME J. 2017 Dec;11(12):2848-2863
pubmed: 28837129
Int J Cancer. 2016 Jun 15;138(12):2915-21
pubmed: 26840624
Microbes Environ. 2017 Dec 27;32(4):300-313
pubmed: 29129876
Immunity. 2017 Oct 17;47(4):739-751.e5
pubmed: 29045903
Nat Rev Immunol. 2018 Feb;18(2):105-120
pubmed: 29034905
Immunity. 2018 Nov 20;49(5):801-818
pubmed: 30462997
ISME J. 2008 Dec;2(12):1183-93
pubmed: 18670396
Parasit Vectors. 2019 Aug 28;12(1):423
pubmed: 31462294
Microbiome. 2020 Apr 2;8(1):46
pubmed: 32241293
PLoS Negl Trop Dis. 2014 Sep 25;8(9):e3170
pubmed: 25255463
World J Gastroenterol. 2017 Sep 7;23(33):6009-6015
pubmed: 28970717
Parasitol Res. 2018 Dec;117(12):3715-3723
pubmed: 30220046
PLoS Genet. 2015 Nov 30;11(11):e1005658
pubmed: 26619199
Sci Rep. 2019 Oct 31;9(1):15703
pubmed: 31673002
Front Immunol. 2018 Oct 12;9:2349
pubmed: 30369927
Semin Cancer Biol. 2019 Apr;55:28-36
pubmed: 29782923
World J Gastrointest Pharmacol Ther. 2017 Nov 6;8(4):201-207
pubmed: 29152406
Parasitol Res. 2019 Apr;118(4):1087-1094
pubmed: 30758662
Sci Rep. 2020 Apr 10;10(1):6234
pubmed: 32277133
Curr Opin Infect Dis. 2016 Oct;29(5):502-7
pubmed: 27479025
Exp Parasitol. 2014 Nov;146:52-63
pubmed: 25300763
Front Microbiol. 2014 Jun 19;5:298
pubmed: 24995004
Infect Immun. 2017 Jul 19;85(8):
pubmed: 28584161
Curr Trop Med Rep. 2016;3:71-74
pubmed: 27525214
Am J Trop Med Hyg. 2016 Jan;94(1):147-55
pubmed: 26572872
Clin Microbiol Infect. 2014 Dec;20(12):1265-75
pubmed: 25273270
Science. 2016 Mar 18;351(6279):1329-33
pubmed: 26847546
J Allergy Clin Immunol. 2016 Sep;138(3):666-675
pubmed: 27476889
Cell. 2016 Oct 6;167(2):444-456.e14
pubmed: 27716507
Mucosal Immunol. 2018 Jan;11(1):144-157
pubmed: 28352104
PLoS Pathog. 2019 Dec 16;15(12):e1008066
pubmed: 31841569
Fam Pract. 2017 Feb;34(1):25-29
pubmed: 27784723
Front Cell Infect Microbiol. 2019 Dec 04;9:401
pubmed: 31867283
Front Immunol. 2020 Feb 11;11:123
pubmed: 32117273
J Microbiol Methods. 2016 Aug;127:68-73
pubmed: 27241828
Microorganisms. 2019 Jan 31;7(2):
pubmed: 30709031
Scand J Gastroenterol. 2013 May;48(5):638-9
pubmed: 23528075
Front Immunol. 2017 Dec 22;8:1864
pubmed: 29312343
Cell Mol Life Sci. 2016 Aug;73(16):3035-51
pubmed: 27032699
Curr Top Behav Neurosci. 2015;26:195-220
pubmed: 25472634
Immunity. 2018 Jul 17;49(1):16-18
pubmed: 30021142
Gastroenterology. 2017 Apr;152(5):1042-1054.e1
pubmed: 28069350
Cell Rep. 2016 May 17;15(7):1527-1541
pubmed: 27160906
Curr Opin Microbiol. 2016 Dec;34:47-52
pubmed: 27501461
Curr Pharm Des. 2014;20(28):4565-9
pubmed: 24180411
Microbiome. 2018 May 1;6(1):81
pubmed: 29716650
Am J Public Health. 2011 Nov;101(11):2068-79
pubmed: 21940915
F1000Res. 2018 Oct 23;7:
pubmed: 30416709
Front Immunol. 2018 Sep 20;9:2128
pubmed: 30298071
Helminthologia. 2018 Jan 27;55(1):1-11
pubmed: 31662622
Front Immunol. 2020 Sep 11;11:2106
pubmed: 33013887
Front Cell Infect Microbiol. 2019 Feb 26;9:34
pubmed: 30863724
Trends Parasitol. 2018 May;34(5):369-377
pubmed: 29567298
Curr Drug Targets. 2014;15(8):762-70
pubmed: 24909808
Int J Food Sci Nutr. 2019 Nov;70(7):781-795
pubmed: 30843443
Nat Commun. 2020 Aug 28;11(1):4333
pubmed: 32859933
Am J Epidemiol. 2008 Sep 15;168(6):647-55
pubmed: 18669932
Am Nat. 2016 Aug;188(2):253-63
pubmed: 27420789
PLoS Negl Trop Dis. 2014 May 22;8(5):e2880
pubmed: 24851867
PLoS Negl Trop Dis. 2017 Nov 2;11(11):e0005916
pubmed: 29095820
Gut. 2020 Oct;69(10):1867-1876
pubmed: 32759302
Microorganisms. 2020 Oct 27;8(11):
pubmed: 33121099
Sci Rep. 2016 May 05;6:25255
pubmed: 27147260
Int J Parasitol. 2017 May;47(6):311-326
pubmed: 28237889
J Parasitol Res. 2017;2017:6865789
pubmed: 29225962

Auteurs

Gianluca Ianiro (G)

Gastroenterology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.

Andrea Iorio (A)

Department of Diagnostic and Laboratory Medicine, Unit of Parasitology and Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Serena Porcari (S)

Gastroenterology Unit, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.

Luca Masucci (L)

Microbiology Unit, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Maurizio Sanguinetti (M)

Microbiology Unit, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Carlo Federico Perno (CF)

Department of Diagnostic and Laboratory Medicine, Unit of Microbiology and Diagnostic Immunology, and Multimodal Laboratory Medicine Research Area, Ospedale Pediatrico Bambino Gesù, Roma, Italy.

Antonio Gasbarrini (A)

Gastroenterology Unit, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.

Lorenza Putignani (L)

Department of Diagnostic and Laboratory Medicine, Unit of Parasitology and Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Giovanni Cammarota (G)

Gastroenterology Unit, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.

Classifications MeSH