Acute StrokeTreatment in Children: Are Adult Guidelines Applicable?
Acute Stroke
Pediatric
TPA
Thrombectomy
Journal
Current treatment options in neurology
ISSN: 1092-8480
Titre abrégé: Curr Treat Options Neurol
Pays: United States
ID NLM: 9815940
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
entrez:
5
5
2022
pubmed:
6
5
2022
medline:
6
5
2022
Statut:
ppublish
Résumé
This article provides an overview into acute treatments in stroke which are widely studied and available for adults and their applicability in the pediatric population. Arterial ischemic stroke is an important cause of morbidity and mortality in the pediatric population. Neurological deficits and etiologies are age-dependent and more challenging to diagnose than in the adult population. Advancements in imaging and treatment modalities including increased treatment windows in acute stroke have led to improvement in the diagnosis and management of pediatric arterial ischemic disease. Accordingly, hyperacute treatments, such as endovascular therapy, are becoming increasingly available in an attempt to improve outcomes in children. Significant scientific and technological advances have transformed the hyperacute treatment of stroke in the recent years, allowing for improvement in the diagnosis and treatment of cerebrovascular pathologies in children. Optimization in the approach, and validation of existing stroke pathways/protocols is expected to further advance acute stroke therapy in pediatric patient care. Given that the lifelong individual, family, and societal burden of acute stroke is likely to be greater than in adults because infants and children surviving stroke live more years with disability, we must be knowledgeable about this pathology and the medical and therapeutic options available for this unique population as detailed in this review.
Identifiants
pubmed: 35509674
doi: 10.1007/s11940-022-00707-6
pmc: PMC9060549
mid: NIHMS1798858
doi:
Types de publication
Journal Article
Langues
eng
Pagination
41-54Subventions
Organisme : NINDS NIH HHS
ID : R01 NS127114
Pays : United States
Déclaration de conflit d'intérêts
COMPETING INTERESTS STATEMENT None declared.
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