Individual-based Modeling of Genome Evolution in Haplodiploid Organisms.
Hymenoptera
ants
arrhenotoky
bees
fate of mutations
haploid males
interpreting genome scans
selection efficacy
Journal
Genome biology and evolution
ISSN: 1759-6653
Titre abrégé: Genome Biol Evol
Pays: England
ID NLM: 101509707
Informations de publication
Date de publication:
03 05 2022
03 05 2022
Historique:
accepted:
20
04
2022
pubmed:
6
5
2022
medline:
12
5
2022
entrez:
5
5
2022
Statut:
ppublish
Résumé
Ants, bees, wasps, bark beetles, and other species have haploid males and diploid females. Although such haplodiploid species play key ecological roles and are threatened by environmental changes, no general framework exists for simulating their genetic evolution. Here, we use the SLiM simulation environment to build a novel model for individual-based forward simulation of genetic evolution in haplodiploids. We compare the fates of adaptive and deleterious mutations and find that selection on recessive mutations is more effective in haplodiploids than in diploids. Our open-source model will foster an understanding of the evolution of sociality and how ecologically important haplodiploid species may respond to changing environments.
Identifiants
pubmed: 35510983
pii: 6576481
doi: 10.1093/gbe/evac062
pmc: PMC9086950
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/T015683/1
Pays : United Kingdom
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.
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