Peculiarities in the panoramic radiograph of patients with secondary hyperparathyroidism due to terminal renal disease: a radiologic controlled comparative study.
Panoramic radiograph
Renal osteodystrophy
Secondary hyperparathyroidism
Terminal renal insufficiency
Journal
Oral radiology
ISSN: 1613-9674
Titre abrégé: Oral Radiol
Pays: Japan
ID NLM: 8806621
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
03
02
2022
accepted:
06
04
2022
pubmed:
6
5
2022
medline:
7
1
2023
entrez:
5
5
2022
Statut:
ppublish
Résumé
The present radiological observational controlled study aims to evaluate the impact of secondary hyperparathyroidism (SHPT) due to chronic kidney disease (CKD) as well as the duration of dialysis on the mineralization of the mandible by standardized qualitative evaluation of digital panoramic radiographs. Panoramic radiographs of CKD patients with SHPT and healthy controls were used for the qualitative analysis of the mandibular cortical index (MCI), the trabecular bone pattern (TBP), and calcification and resorption foci. Radiomorphometric indices were correlated to biochemical parameters and the duration of dialysis using the Spearman Rho test. Group comparisons were conducted using the Mann-Whitney U test and Fisher's exact test at a significance level of α ≤ 0.05. Interrater reliability of two physicians was estimated using Cohen's kappa. Inclusion and exclusion criteria were fulfilled by N = 41 patients. Statistically significant differences in the MCI (p < 0.001) as well as the TBP (p = 0.002) could be detected for the experimental group in comparison to the healthy control group. Focusing on calcification and resorption foci, no statistically significant difference could be detected between the groups (p = 0.244). The level of the detected parathyroid hormone (PTH) significantly correlated with TBP (Rho = 0.338; p = 0.031), while no significant relationship between TBP and the duration of the dialysis could be found. Patients with SHPT due to CKD show statistically significant bone changes in the panoramic radiograph, whereby the grade of trabecular bone change correlates to PTH values.
Identifiants
pubmed: 35511337
doi: 10.1007/s11282-022-00613-2
pii: 10.1007/s11282-022-00613-2
pmc: PMC9813191
doi:
Substances chimiques
Parathyroid Hormone
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
125-132Informations de copyright
© 2022. The Author(s).
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