High-throughput whole-slide scanning to enable large-scale data repository building.

artificial intelligence computational pathology data repository digital pathology machine learning virtual slide whole-slide imaging whole-slide scanning

Journal

The Journal of pathology
ISSN: 1096-9896
Titre abrégé: J Pathol
Pays: England
ID NLM: 0204634

Informations de publication

Date de publication:
07 2022
Historique:
revised: 19 04 2022
received: 17 03 2022
accepted: 02 05 2022
pubmed: 6 5 2022
medline: 8 7 2022
entrez: 5 5 2022
Statut: ppublish

Résumé

Digital pathology and artificial intelligence (AI) rely on digitization of patient material as a necessary first step. AI development benefits from large sample sizes and diverse cohorts, and therefore efforts to digitize glass slides must meet these needs in an efficient and cost-effective manner. Technical innovation in whole-slide imaging has enabled high-throughput slide scanning through the coordinated increase in scanner capacity, speed, and automation. Combining these hardware innovations with automated informatics approaches has enabled more efficient workflows and the opportunity to provide higher-quality imaging data using fewer personnel. Here we review several practical considerations for deploying high-throughput scanning and we present strategies to increase efficiency with a focus on quality. Finally, we review remaining challenges and issue a call to vendors to innovate in the areas of automation and quality control in order to make high-throughput scanning realizable to laboratories with limited resources. © 2022 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.

Identifiants

pubmed: 35511469
doi: 10.1002/path.5923
pmc: PMC9327504
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

383-390

Informations de copyright

© 2022 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.

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Auteurs

Mark D Zarella (MD)

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

Keysabelis Rivera Alvarez (K)

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

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