[Uremic calciphylaxis].
La calciphylaxie urémique.
Calciphylaxie
Calciphylaxis
Dialyse
Dialysis
End-stage renal disease
Insuffisance rénale chronique
Mortality
Mortalité
Traitement
Treatment
Uremic
Urémie
Journal
Nephrologie & therapeutique
ISSN: 1872-9177
Titre abrégé: Nephrol Ther
Pays: France
ID NLM: 101248950
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
20
09
2021
revised:
10
12
2021
accepted:
22
12
2021
pubmed:
7
5
2022
medline:
25
6
2022
entrez:
6
5
2022
Statut:
ppublish
Résumé
Uremic calciphylaxis is a rare disease that affects patients with chronic end-stage renal disease. It is a pathology of the microvessels of the dermis and hypodermis which are calcified and whose thrombosis leads to skin necrosis. Calciphylaxis lesions can be distal and axial. They lead to pain, infection and are associated with denutrition and in high mortality rate (40-80% at 1 year). This general review describes the clinical and para-clinical presentations of calciphylaxis. It summarizes the current knowledge on its pathogenesis and the therapeutical options that can be proposed to improve the management and attempt to reduce the mortality of patients with uremic calciphylaxis.
Identifiants
pubmed: 35514006
pii: S1769-7255(22)00023-2
doi: 10.1016/j.nephro.2021.12.005
pii:
doi:
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
180-188Informations de copyright
Copyright © 2022 Société francophone de néphrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.