Study on mechanism of elemene reversing tumor multidrug resistance based on luminescence pharmacokinetics in tumor cells


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
16 Sep 2020
Historique:
received: 08 01 2020
accepted: 28 06 2020
entrez: 6 5 2022
pubmed: 21 9 2020
medline: 21 9 2020
Statut: epublish

Résumé

While elemene (ELE) can reverse tumor multidrug resistance (MDR), the mechanisms for ELE reversing MDR remain unclear. Numerous studies have suggested that the efflux functionality of ATP-binding cassette (ABC) transporters, not their quantity, is more relevant to tumor MDR. However, no appropriate methods exist for real-time detection of the intracellular drug efflux caused by ABC transporters

Identifiants

pubmed: 35514396
doi: 10.1039/d0ra00184h
pii: d0ra00184h
pmc: PMC9056898
doi:

Types de publication

Journal Article

Langues

eng

Pagination

34928-34937

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

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Auteurs

Liying Chen (L)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Zhi Chen (Z)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.
The First People's Hospital of Jiande Jiande 311600 Zhejiang China.

Shuang Zheng (S)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Luhui Fan (L)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Lixin Zhu (L)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.
Zhejiang Institute for Food and Drug Control Hangzhou 310004 Zhejiang China.

Jiandong Yu (J)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Chaoyuan Tang (C)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Qi Liu (Q)

Department of Dermatology, Johns Hopkins University School of Medicine Baltimore MD 21231 USA.

Yang Xiong (Y)

Department of Pharmaceutical Science, College of Pharmaceutical Science, Zhejiang Chinese Medical University Hangzhou 311400 Zhejiang China.

Classifications MeSH