A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic α-phenylacetamido amides.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
06 Mar 2019
06 Mar 2019
Historique:
received:
06
01
2019
accepted:
04
02
2019
entrez:
6
5
2022
pubmed:
8
3
2019
medline:
8
3
2019
Statut:
epublish
Résumé
The Ugi four component reaction of an aldehyde, amine, isocyanide and an ethanoic acid was effected smoothly in protic ionic liquids ethylammonium nitrate (EAN) and propylammonium nitrate (PAN) to afford analogues of α-phenylacetamido amides in good to excellent isolated yields. The corresponding reactions in [BMIM][PF
Identifiants
pubmed: 35521167
doi: 10.1039/c9ra00118b
pii: c9ra00118b
pmc: PMC9061180
doi:
Types de publication
Journal Article
Langues
eng
Pagination
7652-7663Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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