Adenomyosis decreases the live birth rate but may not affect perinatal outcomes in assisted reproductive cycles.
adenomyosis
in vitro fertilization
obstetrical
oocyte donation
perinatal
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
revised:
27
04
2022
received:
19
01
2022
accepted:
03
05
2022
pubmed:
7
5
2022
medline:
16
11
2022
entrez:
6
5
2022
Statut:
ppublish
Résumé
To determine if uterine adenomyosis is associated with worse perinatal outcomes in ovum donation assisted reproductive treatment cycles. A multicenter and retrospective cohort study in which a total of 3307 patients undergoing an ovum donation cycle in 2018-2019 were included and divided into two groups: adenomyosis (n = 179) and controls (n = 3128). Clinical, obstetrical, and perinatal outcomes were analyzed. A lower live birth rate per embryo transfer was observed in women diagnosed with adenomyosis versus control women: 67/179 (37%) versus 1560/3128 (49.9%), respectively (odds ratio 0.6, 95% confidence interval 0.43-0.83, P = 0.002). There was no statistically significant difference in childbirth delivery method (vaginal versus cesarean section) between the adenomyosis and control groups. Mean gestational age at the time of delivery, newborn length and weight, and incidences of low birth weight, preterm birth, and admission to the neonatal intensive care unit did not differ between the two groups. In addition, in vitro fertilization and perinatal outcomes were similar in patients with diffuse compared with focal adenomyosis. Adenomyosis affects clinical but may not affect perinatal outcomes in ovum donation cycles.
Types de publication
Multicenter Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
918-922Informations de copyright
© 2022 International Federation of Gynecology and Obstetrics.
Références
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