[Experimental study on the relationship between foam pressure difference and foam stability].

Foam stability affects the efficacy and incidence of side effects of foam sclerotherapy. Exploring the relationship between foam pressure difference and foam stability can provide ideas and basis for obtaining more stable foam. In the experiment, sodium cod liver oleate foam was selected, and poloxamer 188 (concentration of 0%, 4%, 8%, 12%) was added to realize the change of foam pressure. By using the self-written program to process the foam pictures, the foam pressure difference and the relationship between the foam stability indicators (water separation rate curve, half-life) and the foam pressure difference were obtained. The results showed that at first the foam pressure increased with the increase of the concentration, and then it decreased with the increase of the concentration and reached a peak at the concentration of 4%. The foam pressure difference decreases continuously with the increase of decay time. When the additive concentration is low, the foam average pressure difference increases. And if the additive concentration is too high, the foam average pressure difference decreases. The smaller the foam pressure difference is, the better the foam stability is. This paper lays a foundation for the research on the stability of foam hardener. 泡沫稳定性影响泡沫硬化疗法的疗效及副作用发生率。探究泡沫压差与泡沫稳定性的关系，能够为获得更稳定的泡沫提供思路和依据。实验选用鱼肝油酸钠泡沫，添加不同浓度的泊洛沙姆188（浓度为0%、4%、8%、12%）实现泡沫压差的改变。使用自编程序处理泡沫图片，获得泡沫压差以及泡沫的稳定性指标（析水率曲线、半衰期）与泡沫压差的关系。研究结果显示，不同时间段内的泡沫压差先随浓度增加而增加，再随浓度增加而减小，在浓度4%时达到峰值。泡沫压差随衰变时间的增加不断减小；添加剂为低浓度时，泡沫平均压差增加，添加剂浓度过高却会使泡沫平均压差减小；泡沫压差越小，泡沫稳定性越好。本文为泡沫硬化剂稳定性的研究奠定基础。.