Isolation of Water-Soluble Metabolites from Marine Invertebrates and Microorganisms.
Hydrophilic
Microbial metabolites
Water-soluble metabolites
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
6
5
2022
pubmed:
7
5
2022
medline:
11
5
2022
Statut:
ppublish
Résumé
The isolation of pure organic compounds from biological sources, reaction media, or other complex molecular matrixes is the first step to overcome before further biological and chemical investigations. While the isolation of chemicals soluble in organic solvents is commonly accomplished, the isolation of water-soluble organic compounds is less often addressed. We present here a simple method for the isolation of water-soluble organic compounds, using adsorptive macroporous resins and reversed-phase chromatography.
Identifiants
pubmed: 35524064
doi: 10.1007/978-1-0716-2273-5_23
doi:
Substances chimiques
Organic Chemicals
0
Solvents
0
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
449-457Informations de copyright
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Bruening RC, Oltz EM, Furukawa J et al (1986) Isolation of tunichrome B-1, a reducing blood pigment of the sea squirt, Ascidia nigra. J Nat Prod 49:193–204
doi: 10.1021/np50044a001
Nakanishi K (1989) Natural products chemistry—past and future. In: Rowe JW (ed) Natural products of woody plants, 1st edn. Springer-Verlag, Berlin, pp 13–26
doi: 10.1007/978-3-642-74075-6_2
McAlpine JB, Hochlowski JE (1994) Isolation and purification of secondary metabolites. In: Gullo VP (ed) The discovery of natural products with therapeutic potential. Butterworth-Heinemann, Boston
Pauli GF, Chen S-N, Friesen JB, McAlpine JB, Jaki BU (2012) Analysis and purification of bioactive natural products: the AnaPurNa study. J Nat Prod 75:1243–1255
doi: 10.1021/np300066q
Shimizu Y (1985) Bioactive marine natural products, with emphasis on handling of water-soluble compounds. J Nat Prod 48:223–235
doi: 10.1021/np50038a005
Shimizu Y (1998) Purification of water-soluble natural products. In: Cannell RJP (ed) Natural products isolation, 1st edn. Humana Press, Totowa, NJ
Wright AE (1998) Isolation of marine natural. In: Cannell RJP (ed) Natural products isolation, 1st edn. Humana Press, Totowa, NJ
Shimizu Y, Li B (2005) Purification of water-soluble natural products. In: Sarker SD, Latif Z, Gray AI (eds) Natural products isolation, 2nd edn. Humana Press, Totowa, NJ
Dufresne C (1998) Isolation by ion-exchange methods. In: Cannell RJP (ed) Natural products isolation, 1st edn. Humana Press, Totowa, NJ
Durham DG (2005) Isolation by ion-exchange methods. In: Sarker SD, Latif Z, Gray AI (eds) Natural products isolation, 2nd edn. Humana Press, Totowa, NJ
Dragull K, Beck JJ (2012) Isolation of natural products by ion-exchange methods. In: Sarker SD, Nahar L (eds) Natural products isolation—methods and protocols, 3rd edn. Humana Press, Totowa, NJ
Houssen WE, Jaspars M (2012) Isolation of marine natural products. In: Sarker SD, Nahar L (eds) Natural products isolation—methods and protocols, 3rd edn. Humana Press, Totowa, NJ
Barrow RA (2005) Isolation of microbial natural products. In: Sarker SD, Latif Z, Gray AI (eds) Natural products isolation, 2nd edn. Humana Press, Totowa, NJ
Umezawa H (1988) Low-molecular-weight enzyme inhibitors and immunomodifiers. In: Goodfellow M, Williams ST, Mordarski M (eds) Actinomycetes in biotechnology, 1st edn. Academic, London, pp 284–325
Umezawa H, Kondo S (1975) Ion-exchange chromatography of aminoglycoside antibiotics. Method Enzymol 43:263–278
doi: 10.1016/0076-6879(75)43087-7
Berlinck RGS, Monteiro AF, Bertonha AF et al (2019) Approaches for the isolation and identification of hydrophilic, light-sensitive, volatile and minor natural products. Nat Prod Rep 36:981–1004
doi: 10.1039/C9NP00009G
Rodríguez JPG, Bernardi DI, Gubiani JR et al (2020) Water-soluble glutamic acid derivatives produced in culture by Penicillium solitum IS1-A from King George Island, Maritime Antarctica. J Nat Prod 83:55–65
doi: 10.1021/acs.jnatprod.9b00635
Shi Q-Q, Lu J, Peng X et al (2018) Cimitriteromone A–G, macromolecular triterpenoid–chromone hybrids from the rhizomes of Cimicifuga foetida. J Org Chem 83:10359–10369
doi: 10.1021/acs.joc.8b01466
Maffioli SI, Fabbretti A, Brandi L et al (2013) Orthoformimycin, a selective inhibitor of bacterial translation elongation from Streptomyces containing an unusual orthoformate. ACS Chem Biol 8:1939–1946
doi: 10.1021/cb4004095
Maffioli SI, Zhang Y, Degen D et al (2017) Antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase. Cell 169:1240–1248
doi: 10.1016/j.cell.2017.05.042
Matsui K, Kan Y, Kikuchi J et al (2020) Stalobacin: discovery of novel lipopeptide antibiotics with potent antibacterial activity against multidrug-resistant bacteria. Med Chem 63:6090–6095
doi: 10.1021/acs.jmedchem.0c00295